Involvement of proteoglycans in tendinopathy
Article
| Article Title | Involvement of proteoglycans in tendinopathy |
|---|---|
| ERA Journal ID | 14617 |
| Article Category | Article |
| Authors | Parkinson, J. (Author), Samiric, T. (Author), Ilic, M. Z. (Author), Cook, J. (Author) and Handley, C. J. (Author) |
| Journal Title | The Journal of Musculoskeletal and Neuronal Interactions |
| Journal Citation | 11 (2), pp. 86-93 |
| Number of Pages | 8 |
| Year | 2011 |
| ISSN | 1108-7161 |
| Web Address (URL) | http://www.ismni.org/jmni/pdf/44/02PARKINSON.pdf |
| Abstract | A major feature of chronic tendinopathy is a change in the nature and organisation of the extracellular matrix of tendon. Increased levels of proteoglycans have been shown in the extracellular matrix of tendinopathic tendons and these appear to influence the increased hydration and swelling of the tissue that is a feature of this condition. There is a paucity of knowledge about proteoglycans in normal and tendinopathic tendons. This review sets out to describe the nature, function and metabolism of proteoglycans present in normal tendon and in tendinopathy and outlines how changes in proteoglycan metabolism may contribute to the development and progression of this disease. |
| Keywords | proteoglycans, tendinopathy, tendon |
| ANZSRC Field of Research 2020 | 429999. Other health sciences not elsewhere classified |
| 310103. Cell metabolism | |
| 320223. Rheumatology and arthritis | |
| Public Notes | Copyright: Authors submitting manuscripts to JMNI retain the copyright of the article if it is published. |
| Byline Affiliations | La Trobe University |
| Monash University | |
| Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q0w23/involvement-of-proteoglycans-in-tendinopathy
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