Involvement of proteoglycans in tendinopathy

Article


Parkinson, J., Samiric, T., Ilic, M. Z., Cook, J. and Handley, C. J.. 2011. "Involvement of proteoglycans in tendinopathy." The Journal of Musculoskeletal and Neuronal Interactions. 11 (2), pp. 86-93.
Article Title

Involvement of proteoglycans in tendinopathy

ERA Journal ID14617
Article CategoryArticle
AuthorsParkinson, J. (Author), Samiric, T. (Author), Ilic, M. Z. (Author), Cook, J. (Author) and Handley, C. J. (Author)
Journal TitleThe Journal of Musculoskeletal and Neuronal Interactions
Journal Citation11 (2), pp. 86-93
Number of Pages8
Year2011
ISSN1108-7161
Web Address (URL)http://www.ismni.org/jmni/pdf/44/02PARKINSON.pdf
Abstract

A major feature of chronic tendinopathy is a change in the nature and organisation of the extracellular matrix of tendon. Increased levels of proteoglycans have been shown in the extracellular matrix of tendinopathic tendons and these appear to influence the increased hydration and swelling of the tissue that is a feature of this condition. There is a paucity of knowledge about proteoglycans in normal and tendinopathic tendons. This review sets out to describe the nature, function and metabolism of proteoglycans present in normal tendon and in tendinopathy and outlines how changes in proteoglycan metabolism may contribute to the development and progression of this disease.

Keywordsproteoglycans, tendinopathy, tendon
ANZSRC Field of Research 2020429999. Other health sciences not elsewhere classified
310103. Cell metabolism
320223. Rheumatology and arthritis
Public Notes

Copyright: Authors submitting manuscripts to JMNI retain the copyright of the article if it is published.

Byline AffiliationsLa Trobe University
Monash University
Institution of OriginUniversity of Southern Queensland
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