Optimal targeting of hepatitis C virus treatment among injecting drug users to those not enrolled in methadone maintenance programs
Article
Article Title | Optimal targeting of hepatitis C virus treatment among injecting drug users to those not enrolled in methadone maintenance programs |
---|---|
ERA Journal ID | 13492 |
Article Category | Article |
Authors | Zeiler, Irmgard (Author), Langlands, Trevor (Author), Murray, John M. (Author) and Ritter, Alison (Author) |
Journal Title | Drug and Alcohol Dependence |
Journal Citation | 110 (3), pp. 228-233 |
Number of Pages | 6 |
Year | 2010 |
Publisher | Elsevier |
Place of Publication | Ireland |
ISSN | 0376-8716 |
1879-0046 | |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.drugalcdep.2010.03.006 |
Web Address (URL) | http://www.sciencedirect.com/science/article/pii/S0376871610001067 |
Abstract | Background: This work used mathematical modelling to explore effective policy for Hepatitis C virus (HCV) treatment in Australia in the context of methadone maintenance treatment (MMT). Results: Although increasing levels of HCV treatment decrease chronic infection prevalence, initially numbers Conclusions: Contrary to generally held beliefs regarding HCV treatment the majority of therapy should be allocated to those that are still actively injecting. This is due to rates of reinfection and to the high turnover of individuals in MMT. Higher adherence to HCV therapy in MMT would need to be achieved before this changed. |
Keywords | hepatitis C modelling; mathematical modelling; methadone treatment |
Contains Sensitive Content | Does not contain sensitive content |
ANZSRC Field of Research 2020 | 490409. Ordinary differential equations, difference equations and dynamical systems |
490102. Biological mathematics | |
320211. Infectious diseases | |
Public Notes | File reproduced in accordance with the copyright policy of the publisher/author. |
Byline Affiliations | University of New South Wales |
Department of Mathematics and Computing |
https://research.usq.edu.au/item/9zxqv/optimal-targeting-of-hepatitis-c-virus-treatment-among-injecting-drug-users-to-those-not-enrolled-in-methadone-maintenance-programs
Download files
1984
total views387
total downloads0
views this month0
downloads this month