The globally disseminated M1T1 clone of Group A streptococcus evades autophagy for intracellular replication
Article
Article Title | The globally disseminated M1T1 clone of Group A streptococcus evades autophagy for intracellular replication |
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ERA Journal ID | 2525 |
Article Category | Article |
Authors | Barnett, Timothy C. (Author), Liebl, David (Author), Seymour, Lisa M. (Author), Gillen, Christine M. (Author), Yan Lim, Jin (Author), LaRock, Christopher N. (Author), Davies, Mark R. (Author), Schulz, Benjamin L. (Author), Nizet, Victor (Author), Teasdale, Rohan D. (Author) and Walker, Mark J. (Author) |
Journal Title | Cell Host and Microbe |
Journal Citation | 14 (6), pp. 675-682 |
Number of Pages | 8 |
Year | 2013 |
Place of Publication | Cambridge, MA. United States |
ISSN | 1931-3128 |
1934-6069 | |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.chom.2013.11.003 |
Abstract | Autophagy is reported to be an important innate immune defense against the intracellular bacterial pathogen Group A Streptococcus (GAS). However, the GAS strains examined to date belong to serotypes infrequently associated with human disease. We find that the globally disseminated serotype M1T1 clone of GAS can evade autophagy and replicate |
Keywords | autophagy; Group A Streptococcus (GAS); adaptor protein; cysteine proteinase; NBR1 protein; NDP52 protein; protein p62; speb protein; cysteine proteinase |
ANZSRC Field of Research 2020 | 320701. Medical bacteriology |
310702. Infectious agents | |
Public Notes | © 2013 Elsevier Inc. Published version deposited but restricted in accordance with the copyright policy of the publisher. |
Byline Affiliations | University of Queensland |
University of California, United States | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q25z2/the-globally-disseminated-m1t1-clone-of-group-a-streptococcus-evades-autophagy-for-intracellular-replication
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