Saturated fatty acids, linseed components and high amylose wheat in attenuation of diet-induced metabolic syndrome
PhD Thesis
Title | Saturated fatty acids, linseed components and high amylose wheat in attenuation of diet-induced metabolic syndrome |
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Type | PhD Thesis |
Authors | |
Author | Shafie, Siti Raihanah binti |
Supervisor | Brown, Lindsay |
Kauter, Kate | |
Panchal, Sunil | |
Institution of Origin | University of Southern Queensland |
Qualification Name | Doctor of Philosophy |
Number of Pages | 231 |
Year | 2017 |
Abstract | Metabolic syndrome is a syndrome characterised by central obesity, dyslipidaemia, hypertension, fatty liver disease and insulin resistance that ultimately raises the risk of heart disease, diabetes, stroke, cancers and osteoarthritis. In combating metabolic syndrome, lifestyle changes are considered the most important initial steps which include a healthy, well-balanced diet and increased physical activity. Enrichment of beneficial fatty acids and incorporation of functional foods and bioactive nutrients are part of healthy dietary regimes in treating metabolic syndrome. These strategies provide options other than drug therapies that may cause adverse effects. Nevertheless, the effectiveness of these foods or bioactive nutrients in treating metabolic syndrome has yet to be fully explored. Therefore, in this thesis, I examined the physiological effects of individual saturated fatty acids (lauric, myristic, palmitic and stearic acid), linseed components (lignans, raw linseed and defatted linseed) and Male Wistar rats fed with either diet containing 20% of lauric, myristic, palmitic, or stearic acid or corn-starch or high-carbohydrate, high-fat diet for 16 weeks Linseed is a rich source of plant lignans such as secoisolariciresinol diglucoside, as well as dietary fibre. Supplementation of lignan (0.03%) and defatted The studies in this thesis provided evidence that not all saturated fatty acids are equal, with lauric acid producing fewer pathophysiological changes in most parameters than other saturated fatty acids in this model of diet-induced metabolic syndrome. Studies from linseed components and high amylose wheat clearly indicate that these foods or food components have the potential to reverse most of the risk factors associated with metabolic syndrome. The most likely mechanisms of these food or food components are through the cardioprotective and hepatoprotective effects |
Keywords | metabolic syndrome; fatty acids; functional foods |
ANZSRC Field of Research 2020 | 321099. Nutrition and dietetics not elsewhere classified |
Byline Affiliations | School of Health and Wellbeing |
https://research.usq.edu.au/item/q45x3/saturated-fatty-acids-linseed-components-and-high-amylose-wheat-in-attenuation-of-diet-induced-metabolic-syndrome
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