Numerical solution and stability analysis of a childhood-disease model with vaccination and relapse

Article


Rabiu, Musa, Adeniji, Saidat Morenike and Jimoh, Folashade Mistura. 2020. "Numerical solution and stability analysis of a childhood-disease model with vaccination and relapse." Applied Mathematics E-Notes. 20, pp. 499-515.
Article Title

Numerical solution and stability analysis of a childhood-disease model with vaccination and relapse

ERA Journal ID41462
Article CategoryArticle
AuthorsRabiu, Musa, Adeniji, Saidat Morenike and Jimoh, Folashade Mistura
Journal TitleApplied Mathematics E-Notes
Journal Citation20, pp. 499-515
Number of Pages17
Year2020
PublisherTsinghua University Press
Place of PublicationTaiwan
ISSN1607-2510
Web Address (URL)https://www.math.nthu.edu.tw/~amen/
AbstractIn this research, a childhood disease model that incorporates relapse and vaccination was developed and systematically analyzed using sets of non-linear Ordinary Di§erential Equations. The model exhibits disease-free equilibrium which is locally and globally asymptotically stable whenever the threshold parameter Ro is less than unity and unstable otherwise. It also exhibits endemic equilibrium which was proved to be locally asymptotically stable whenever Ro is greater than unity. The model was then modiÖed to include vaccination programme capable of reducing disease burden. The global stability analysis of the endemic equilibrium points was carried out using geometric and compound matrix approach satisfying the Bendixon criterion when Rv > 1. The numerical solution of the model was performed using Adams method coded in Python Programming Language to explore the biological implication of force of infection, vaccination and relapse. The result shows that for the disease to be eradicated, the vaccination rate f must be robust, relapse rate  reduced and the contact rate among children should be avoided or minimized.
KeywordsMathematical modelling
Contains Sensitive ContentDoes not contain sensitive content
ANZSRC Field of Research 2020401706. Numerical modelling and mechanical characterisation
Public NotesFiles associated with this item cannot be displayed due to copyright restrictions.
Byline AffiliationsUniversity of KwaZulu-Natal, South Africa
University of Ilorin, Nigeria
Alhikmah University, Nigeria
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