# Advection-dispersion in symmetric field-flow fractionation channels

Working paper

*Advection-dispersion in symmetric field-flow fractionation channels.*Toowoomba, Australia. University of Southern Queensland.

Title | Advection-dispersion in symmetric field-flow fractionation channels |
---|---|

Report Type | Working paper |

Authors | Suslov, Sergey A. (Author) and Roberts, A. J. (Author) |

Institution of Origin | University of Southern Queensland |

Number of Pages | 23 |

Year | 1998 |

Publisher | University of Southern Queensland |

Place of Publication | Toowoomba, Australia |

Abstract | We model the evolution of the concentration field of macromolecules in a symmetric field-flow fractionation (FFF) channel by a one-dimensional advection-diffusion equation. The coefficients are precisely determined from the fluid dynamics. This model gives quantitative predictions of the time of elution of the molecules and the width in time of the concentration pulse. The model is rigorously supported by centre manifold theory. Errors of the derived model are quantified for improved predictions if necessary. The advection-diffusion equation is used to find that the optimal condition in a symmetric FFF for the separation of two species of molecules with similar diffusivities involves a high rate of crossflow. |

Keywords | field-flow; FFF; field-flow fractionation |

ANZSRC Field of Research 2020 | 401204. Computational methods in fluid flow, heat and mass transfer (incl. computational fluid dynamics) |

490399. Numerical and computational mathematics not elsewhere classified | |

490109. Theoretical and applied mechanics | |

Public Notes | File reproduced in accordance with the copyright policy of the publisher/author. |

Byline Affiliations | Department of Mathematics and Computing |

https://research.usq.edu.au/item/9yzv7/advection-dispersion-in-symmetric-field-flow-fractionation-channels

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