Arterial oxygen desaturation kinetics during apnea

Article


Stewart, Ian B., Bulmer, Andrew C., Sharman, James E. and Ridgway, Lynne. 2005. "Arterial oxygen desaturation kinetics during apnea." Medicine and Science in Sports and Exercise. 37 (11), pp. 1871-1876. https://doi.org/10.12490/01.mss.0000176305.51360.7e
Article Title

Arterial oxygen desaturation kinetics during apnea

ERA Journal ID9788
Article CategoryArticle
AuthorsStewart, Ian B. (Author), Bulmer, Andrew C. (Author), Sharman, James E. (Author) and Ridgway, Lynne (Author)
Journal TitleMedicine and Science in Sports and Exercise
Journal Citation37 (11), pp. 1871-1876
Number of Pages6
Year2005
PublisherLippincott Williams & Wilkins
Place of PublicationUSA
ISSN0195-9131
1530-0315
Digital Object Identifier (DOI)https://doi.org/10.12490/01.mss.0000176305.51360.7e
Abstract

Purpose: To quantify the rate of arterial oxygen desaturation during apnea in freedivers. Methods: Ten freedivers and ten controls undertook five maximal face immersion apneas in 10°C water separated by 2 min of recovery. Electrocardiogram (ECG), blood pressure, and pulse oximetry were recorded continuously. Peripheral blood flow was measured by calf plethysmography every 30 s, and venous blood samples were collected at rest and after apneas 1, 3, and 5. The blood was analyzed for hematocrit (Hct), lactate, and hemoglobin (Hb) concentration. The arterial oxygen saturation (SaO2) data were curve fitted with both a sigmoid and two-slope continuous function. Results: Apnea duration increased with successive attempts, with freedivers achieving significantly longer maximal apneas (trained 246 ± 44 s, untrained 129 ± 39 s, P < 0.001). Compared with controls, freedivers displayed a significant change from baseline in heart rate (trained -27.2 ± 9.5 bpm, untrained -19.7 ± 9.3 bpm, P < 0.001) and mean arterial pressure (MAP) (trained 48 ± 20.7 mm Hg, untrained 37 ± 10.0 mm Hg, P = 0.002), but no difference existed in peripheral blood flow, Hct, lactate, or Hb. The maximal slope of the SaO2 sigmoid curve was not significantly different between the groups (trained -0.16 ± 0.05%·s -1, untrained -0.15 ± 0.06%·s-1, P = 0.26), but the ΔSaO2/Δt obtained from the two-slope continuous model indicated that 85% of the variance in the freedivers ΔSaO 2/At could be explained by the apnea-induced bradycardia, preapnea vital capacity, and Hb concentration. Conclusions: The sigmoidal function provided no quantifiable difference in the rate of oxygen desaturation. The two-slope continuous method, however, indicated that freedivers who had larger oxygen stores and produced the largest bradycardia were able to slow the ΔSaO2/Δt to two to three times that of the least marked response.

Keywordsfreedivers; arterial oxygen desaturation; breath hold; diving response; sigmoid logistic function
ANZSRC Field of Research 2020420702. Exercise physiology
Public Notes

Files associated with this item cannot be displayed due to copyright restrictions.

Byline AffiliationsQueensland University of Technology
University of Queensland
Permalink -

https://research.usq.edu.au/item/9zx17/arterial-oxygen-desaturation-kinetics-during-apnea

  • 1939
    total views
  • 9
    total downloads
  • 1
    views this month
  • 0
    downloads this month

Export as

Related outputs

Searching for scientific Mozarts: get em' while they're young
Donovan, Jennifer, Haeusler, Carole and Stewart, Ian. 2013. "Searching for scientific Mozarts: get em' while they're young." The Conversation. 18 June 2013, pp. 1-4.
Endurance exercise and DNA stability: is there a link to duration and intensity?
Reichhold, Stefanie, Neubauer, Oliver, Bulmer, Andrew C., Knasmuller, Siegfried and Wagner, Karl-Heinz. 2009. "Endurance exercise and DNA stability: is there a link to duration and intensity?" Mutation Research/Reviews in Mutation Research. 682 (1), pp. 28-38. https://doi.org/10.1016/j.mrrev.2009.02.002
Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administration
Morgan, Michael, Bulmer, Andrew C., Woodruff, Trent M., Proctor, Lavinia M., Williams, Hua M., Stocks, Shelli Z., Pollitt, Sandra, Taylor, Stephen M. and Shiels, Ian A.. 2008. "Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administration." European Journal of Pharmaceutical Sciences. 33 (4-5), pp. 390-398. https://doi.org/10.1016/j.ejps.2008.01.009
In vitro permeability and metabolic stability of bile pigments and the effects of hydrophilic and lipophilic modifcation of biliverdin
Bulmer, Andrew C., Blanchfield, Joanne T., Coombes, Jeff S. and Toth, Istvan. 2008. "In vitro permeability and metabolic stability of bile pigments and the effects of hydrophilic and lipophilic modifcation of biliverdin." Bioorganic and Medicinal Chemistry. 16 (7), pp. 3616-3625. https://doi.org/10.1016/j.bmc.2008.02.2008
Effects of maximal static apnea on antioxidant defenses in trained free divers
Bulmer, Andrew C., Coombes, Jeff S., Sharman, James E. and Stewart, Ian B.. 2008. "Effects of maximal static apnea on antioxidant defenses in trained free divers." Medicine and Science in Sports and Exercise. 40 (7), pp. 1307-1313. https://doi.org/10.1249/MSS.0b013e31816a7188
Improved resistance to serum oxidation in Gilbert's Syndrome: a mechanism for cardiovascular protection
Bulmer, Andrew C., Blanchfield, Joanne T., Toth, Istvan, Fassett, Robert G. and Coombes, Jeff S.. 2008. "Improved resistance to serum oxidation in Gilbert's Syndrome: a mechanism for cardiovascular protection." Atherosclerosis. 199, pp. 390-396. https://doi.org/10.1016/j.atherosclerosis.2007.11.022
The anti-mutagenic properties of bile pigments
Bulmer, Andrew C., Ried, K., Blanchfield, Joanne T. and Wagner, Karl-Heinz. 2008. "The anti-mutagenic properties of bile pigments." Mutation Research/Reviews in Mutation Research. 658, pp. 28-41. https://doi.org/10.1016j.mrrev.2007.05.001
The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test
Bulmer, Andrew C., Ried, K., Coombes, Jeff S., Blanchfield, Joanne T., Toth, Istvan and Wagner, Karl-Heinz. 2007. "The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test." Mutation Research: Genetic Toxicology and Environmental Mutagenesis. 629, pp. 122-132. https://doi.org/10.1016/j.mrgentox.2007.01.008
Optimising exercise training in peripheral arterial disease
Bulmer, Andrew C. and Coombes, Jeff S.. 2004. "Optimising exercise training in peripheral arterial disease." Sports Medicine. 34 (14), pp. 983-1003. https://doi.org/10.2165/00007256-200434140-00004