The development and evaluation of DNA vaccines against whooping cough using a murine respiratory model of infection

PhD Thesis


Fry, Scott Robert. 2006. The development and evaluation of DNA vaccines against whooping cough using a murine respiratory model of infection. PhD Thesis Doctor of Philosophy. University of Southern Queensland.
Title

The development and evaluation of DNA vaccines against whooping cough using a murine respiratory model of infection

TypePhD Thesis
Authors
AuthorFry, Scott Robert
SupervisorMukkur, T. K. S.
Daggard, Grant
Institution of OriginUniversity of Southern Queensland
Qualification NameDoctor of Philosophy
Number of Pages423
Year2006
Abstract

In this study, a suite of single antigen DNA vaccines, combination DNA vaccines and dual modality vaccines, were developed and evaluated for their potential to induce humoral and cell-mediated immune responses, and protective efficacy against Bordetella pertussis, the aetiological agent of whooping cough, using the mouse respiratory challenge model.

KeywordsDNA vaccines; whooping cough; Bordetella pertussis
ANZSRC Field of Research 2020320404. Cellular immunology
Byline AffiliationsDepartment of Biological and Physical Sciences
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