Needleless connector decontamination for prevention of central venous access device infection: A pilot randomized controlled trial

Article


Rickard, Claire M., Flynn, Julie, Larsen, Emily, Mihala, Gabor, Playford, E Geoffrey, Shaw, Joanie, Keogh, Samantha, Ullman, Amanda, Zhang, Li, Gavin, Nicole, Kleidon, Tricia, Chopra, Vineet, McCarthy, Alexandra L., Rocha, Patricia Kuerten and Marsh, Nicole. 2021. "Needleless connector decontamination for prevention of central venous access device infection: A pilot randomized controlled trial." American Journal of Infection Control. 49 (2), pp. 269-273. https://doi.org/10.1016/j.ajic.2020.07.026
Article Title

Needleless connector decontamination for prevention of central venous access device infection: A pilot randomized controlled trial

ERA Journal ID15641
Article CategoryArticle
AuthorsRickard, Claire M. (Author), Flynn, Julie (Author), Larsen, Emily (Author), Mihala, Gabor (Author), Playford, E Geoffrey (Author), Shaw, Joanie (Author), Keogh, Samantha (Author), Ullman, Amanda (Author), Zhang, Li (Author), Gavin, Nicole (Author), Kleidon, Tricia (Author), Chopra, Vineet (Author), McCarthy, Alexandra L. (Author), Rocha, Patricia Kuerten (Author) and Marsh, Nicole (Author)
Journal TitleAmerican Journal of Infection Control
Journal Citation49 (2), pp. 269-273
Number of Pages5
Year2021
Place of PublicationUnited States
ISSN0161-6005
0196-6553
1527-3296
Digital Object Identifier (DOI)https://doi.org/10.1016/j.ajic.2020.07.026
Web Address (URL)https://www.sciencedirect.com/science/article/pii/S0196655320307318
Abstract

Pilot randomized controlled trial (180 patients) of needleless connector decontamination. Central line-associated bloodstream infection occurred in 2% (1/61) of 70% isopropyl alcohol (IPA) wipe, 2% (1/59) of 70% IPA cap, and zero (0/58) infections in 2% chlorhexidine gluconate in 70% IPA wipe patients. Larger definitive trials are feasible and needed.

KeywordsCatheter related infections; Catheterization; Central venous; Chlorhexidine gluconate; Infection control; Isopropyl alcohol
ANZSRC Field of Research 2020420506. Sub-acute care
420501. Acute care
Byline AffiliationsGriffith University
Department of Health, Queensland
Institution of OriginUniversity of Southern Queensland
Permalink -

https://research.usq.edu.au/item/q6w4x/needleless-connector-decontamination-for-prevention-of-central-venous-access-device-infection-a-pilot-randomized-controlled-trial

  • 76
    total views
  • 37
    total downloads
  • 0
    views this month
  • 0
    downloads this month

Export as

Related outputs

Controlling peripheral intravenous catheter failure by needleless connector design: A pilot randomised controlled trial
Marsh, Nicole, Larsen, Emily, O'Brien, Catherine, Peach, Hannah, Keogh, Samantha, Davies, Karen, Mihala, Gabor, Hewer, Barbara, Booker, Catriona, McCarthy, Alexandra L., Flynn, Julie and Rickard, Claire M.. 2023. "Controlling peripheral intravenous catheter failure by needleless connector design: A pilot randomised controlled trial." Journal of Clinical Nursing. 32 (21-22), pp. 7909-7919. https://doi.org/10.1111/jocn.16852
Safety and efficacy of midline catheters versus peripheral intravenous catheters: A pilot randomized controlled trial
Marsh, Nicole, Larsen, Emily N., O'Brien, Catherine, Ware, Robert S., Kleidon, Tricia M., Groom, Peter, Hewer, Barbara, Alexandrou, Evan, Flynn, Julie, Woollett, Kaylene and Rickard, Claire M.. 2022. "Safety and efficacy of midline catheters versus peripheral intravenous catheters: A pilot randomized controlled trial." International Journal of Nursing Practice. 29 (2), pp. 1-11. https://doi.org/10.1111/ijn.13110
Comparing compliance with commencement and use of two partograph designs for women in active labour: A randomised controlled trial
Lee, Nigel, Flynn, Julie, Gao, Yu and Kildea, Sue. 2023. "Comparing compliance with commencement and use of two partograph designs for women in active labour: A randomised controlled trial." Women and Birth. 36 (1), pp. e17-e24. https://doi.org/10.1016/j.wombi.2022.04.004
Reimagining the role of nursing education in emissions reduction
Ward, Aletha, Heart, Diane, Richards, Catelyn, Bayliss, Luke T., Holmes, Mark, Keogh, Samantha and Best, Odette. 2022. "Reimagining the role of nursing education in emissions reduction." Teaching and Learning in Nursing. 17 (4), pp. 410-416. https://doi.org/10.1016/j.teln.2022.02.003
Evaluating methods for the use and decontamination of needleless connectors: A qualitative inquiry
Larsen, Emily N., August, Deanne, Keogh, Samantha, Flynn, Julie, Ullman, Amanda J., Marsh, Nicole, Cooke, Marie, McCarthy, Alexandra L. and Rickard, Claire M.. 2022. "Evaluating methods for the use and decontamination of needleless connectors: A qualitative inquiry." Infection, Disease and Health. 27 (4), pp. 175-183. https://doi.org/10.1016/j.idh.2022.04.002
Evaluating the spatial distribution of endangered frogs in Northern Queensland and the threats to their continued survival
Larsen, Emily. 2022. Evaluating the spatial distribution of endangered frogs in Northern Queensland and the threats to their continued survival. Masters Thesis Master of Science. University of Southern Queensland. https://doi.org/10.26192/yyw18
Response to the Letter to the Editor regarding “Methods for microbial needleless connector decontamination: A systematic review and meta-analysis”
Flynn, Julie M., Larsen, Emily N., Keogh, Samantha, Ullman, Amanda J. and Rickard, Claire M.. 2019. "Response to the Letter to the Editor regarding “Methods for microbial needleless connector decontamination: A systematic review and meta-analysis”." American Journal of Infection Control. 47 (12), pp. 1521-1522. https://doi.org/10.1016/j.ajic.2019.07.002
Securement methods for peripheral venous catheters to prevent failure: a randomised controlled pilot trial
Marsh, Nicole, Webster, Joan, Flynn, Julie, Mihala, Gabor, Hewer, Barbara, Fraser, John and Rickard, Claire. 2015. "Securement methods for peripheral venous catheters to prevent failure: a randomised controlled pilot trial." The Journal of Vascular Access. 16 (3), pp. 237-244. https://doi.org/10.5301/jva.5000348
Needleless connector decontamination: To use, or not to use, chlorhexidine?
Flynn, Julie, Slater, Karen, Cooke, Marie and Rickard, Claire M.. 2018. "Needleless connector decontamination: To use, or not to use, chlorhexidine?" American Journal of Infection Control. 46 (8), pp. 959-960. https://doi.org/10.1016/j.ajic.2018.03.003
An observational study of nurses’ intravenous flush and medication practice in the clinical setting
Keogh, Samantha, Shelverton, Caroline, Flynn, Julie, Davies, Karen, Marsh, Nicole and Rickard, Claire M.. 2017. "An observational study of nurses’ intravenous flush and medication practice in the clinical setting." Vascular Access. 3 (1), pp. 1-18. https://doi.org/10.3316/informit.629496319613481
Evaluating methods for effective decontamination of central venous access devices needleless connectors in adult hospital patients: A pilot randomised control trial protocol
Flynn, Julie M., Keogh, Samantha, Zhang, Li and Rickard, Claire M.. 2017. "Evaluating methods for effective decontamination of central venous access devices needleless connectors in adult hospital patients: A pilot randomised control trial protocol." Vascular Access. 3 (2), pp. 1-18. https://doi.org/10.3316/informit.632663924727375
The MIDLINE trial – managing intravenous devices among patients with limited vascular access or prolonged therapy: a pilot randomised control trial protocol
Marsh, Nicole, Larsen, Emily, Flynn, Julie, O’Brien, Catherine, Kleidon, Tricia, Groom, Peter, Hewer, Barbara and Rickard, Claire M.. 2020. "The MIDLINE trial – managing intravenous devices among patients with limited vascular access or prolonged therapy: a pilot randomised control trial protocol." Vascular Access. 6 (1), pp. 20-24. https://doi.org/10.33235/va.6.1.20-24
Maternal positioning with flexed thighs to correct foetal occipito-posterior position in labour: A systematic review and meta-analysis
Lee, Nigel, Munro, Victoria, Oliver, Kirra and Flynn, Julie. 2021. "Maternal positioning with flexed thighs to correct foetal occipito-posterior position in labour: A systematic review and meta-analysis." Midwifery. 99. https://doi.org/10.1016/j.midw.2021.103008
Disinfection of Needleless Connector Hubs: Clinical Evidence Systematic Review
Moureau, Nancy L. and Flynn, Julie. 2015. "Disinfection of Needleless Connector Hubs: Clinical Evidence Systematic Review." Nursing Research and Practice. 2015, pp. 1-20. https://doi.org/10.1155/2015/796762
Nursing and midwifery practice for maintenance of vascular access device patency. A cross-sectional survey
Keogh, Samantha, Flynn, Julie, Marsh, Nicole, Higgins, Niall, Davies, Karen and Rickard, Claire M.. 2015. "Nursing and midwifery practice for maintenance of vascular access device patency. A cross-sectional survey." International Journal of Nursing Studies. 52 (11), pp. 1678-1685. https://doi.org/10.1016/j.ijnurstu.2015.07.001
Alcohol Caps or Alcohol Swabs With and Without Chlorhexidine: An In Vitro Study of 648 Episodes of Intravenous Device Needleless Connector Decontamination
Flynn, Julie M., Rickard, Claire M., Keogh, Samantha and Zhang, Li. 2017. "Alcohol Caps or Alcohol Swabs With and Without Chlorhexidine: An In Vitro Study of 648 Episodes of Intravenous Device Needleless Connector Decontamination." Infection Control and Hospital Epidemiology. 38 (5), pp. 617-619. https://doi.org/10.1017/ice.2016.330
Infection risks associated with peripheral vascular catheters
Zhang, Li, Cao, Siyu, Marsh, Nicole, Ray-Barruel, Gillian, Flynn, Julie, Larsen, Emily and Rickard, Claire M.. 2016. "Infection risks associated with peripheral vascular catheters." Journal of Infection Prevention. 17 (5), pp. 207-213. https://doi.org/10.1177/1757177416655472
Methods for microbial needleless connector decontamination: A systematic review and meta-analysis
Flynn, Julie M., Larsen, Emily N., Keogh, Samantha, Ullman, Amanda J. and Rickard, Claire M.. 2019. "Methods for microbial needleless connector decontamination: A systematic review and meta-analysis." American Journal of Infection Control. 47 (8), pp. 956-962. https://doi.org/10.1016/j.ajic.2019.01.002
Varied flushing frequency and volume to prevent peripheral intravenous catheter failure: a pilot, factorial randomised controlled trial in adult medical-surgical hospital patients
Keogh, Samantha, Flynn, Julie, Marsh, Nicole, Mihala, Gabor, Davies, Karen and Rickard, Claire. 2016. "Varied flushing frequency and volume to prevent peripheral intravenous catheter failure: a pilot, factorial randomised controlled trial in adult medical-surgical hospital patients." Trials. 17 (1), pp. 1-10. https://doi.org/10.1186/s13063-016-1470-6
Central venous Access device SeCurement And Dressing Effectiveness for peripherally inserted central catheters in adult acute hospital patients (CASCADE): a pilot randomised controlled trial
Chan, Raymond J., Northfield, Sarah, Larsen, Emily, Mihala, Gabor, Ullman, Amanda, Hancock, Peter, Marsh, Nicole, Gavin, Nicole, Wyld, David, Allworth, Anthony, Russell, Emily, Choudhury, Md Abu, Flynn, Julie and Rickard, Claire M.. 2017. "Central venous Access device SeCurement And Dressing Effectiveness for peripherally inserted central catheters in adult acute hospital patients (CASCADE): a pilot randomised controlled trial." Trials. 18 (1), pp. 1-13. https://doi.org/10.1186/s13063-017-2207-x
Flushing of peripheral intravenous catheters: A pilot, factorial, randomised controlled trial of high versus low frequency and volume in paediatrics
Kleidon, Tricia M., Keogh, Samantha, Flynn, Julie, Schults, Jessica, Mihala, Gabor and Rickard, Claire M.. 2020. "Flushing of peripheral intravenous catheters: A pilot, factorial, randomised controlled trial of high versus low frequency and volume in paediatrics." Journal of Paediatrics and Child Health. 56 (1), pp. 22-29. https://doi.org/10.1111/jpc.14482
Implementation and evaluation of short peripheral intravenous catheter flushing guidelines: a stepped wedge cluster randomised trial
Keogh, Samantha, Shelverton, Caroline, Flynn, Julie, Mihala, Gabor, Mathew, Saira, Davies, Karen M., Marsh, Nicole and Rickard, Claire M.. 2020. "Implementation and evaluation of short peripheral intravenous catheter flushing guidelines: a stepped wedge cluster randomised trial." BMC Medical. 18 (1), pp. 1-11. https://doi.org/10.1186/s12916-020-01728-1
Clinically-indicated replacement versus routine replacement of peripheral venous catheters [Review]
Webster, J., Osborne, S., Rickard, C. M. and Hall, J.. 2010. "Clinically-indicated replacement versus routine replacement of peripheral venous catheters [Review]." Cochrane Database of Systematic Reviews. 2010 (3), pp. 1-41.
Clinically-indicated replacement versus routine replacement of peripheral venous catheters [Review]
Webster, J., Osborne, S., Rickard, C. M. and New, K.. 2013. "Clinically-indicated replacement versus routine replacement of peripheral venous catheters [Review]." Cochrane Database of Systematic Reviews. 2013 (4), pp. 1-42.
Clinically-indicated replacement versus routine replacement of peripheral venous catheters [Review]
Webster, J., Osborne, S., Rickard, C. and New, K.. 2015. "Clinically-indicated replacement versus routine replacement of peripheral venous catheters [Review]." Cochrane Database of Systematic Reviews. 2015 (8), pp. 1-45. https://doi.org/10.1002/14651858.CD007798.pub4
Prevention of Occlusion of cEnTral lInes for Children with cancer: An implementation study
Ullman, Amanda J., Condon, Paula, Edwards, Rachel, Gibson, Victoria, Takashima, Mari, Schults, Jessica, Dean, Anna, Cattanach, Paula, Nicholls, Wayne, Osborne, Sonya, Rickard, Claire M., Cooke, Marie and Kleidon, Tricia. 2020. "Prevention of Occlusion of cEnTral lInes for Children with cancer: An implementation study." Journal of Paediatrics and Child Health. 56 (12), pp. 1875-1884. https://doi.org/10.1111/jpc.15067
Clinically-indicated replacement versus routine replacement of peripheral venous catheters
Webster, Joan, Osborne, Sonya, Rickard, Claire M and Marsh, Nicole. 2019. "Clinically-indicated replacement versus routine replacement of peripheral venous catheters." Cochrane Database of Systematic Reviews. 2019 (1), pp. i-55. https://doi.org/10.1002/14651858.CD007798.pub5
Sterile v aseptic non-touch technique for needle-less connector care on central venous access devices in a bone marrow transplant population: A comparative study
Flynn, Julie M., Keogh, Samantha J. and Gavin, Nicole C.. 2015. "Sterile v aseptic non-touch technique for needle-less connector care on central venous access devices in a bone marrow transplant population: A comparative study." European Journal of Oncology Nursing (EJON). 19 (6), pp. 694-700. https://doi.org/10.1016/j.ejon.2015.05.003
Clinically-indicated replacement versus routine replacement of peripheral venous catheters [Review]
Webster, Joan, Osborne, Sonya, Rickard, Clare M. and New, Karen. 2013. "Clinically-indicated replacement versus routine replacement of peripheral venous catheters [Review]." Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.CD007798.pub3
A review of the educational needs of nurses administering cancer chemotherapy in rural and remote areas of Queensland
McCarthy, A. and Hegney, D.. 2001. "A review of the educational needs of nurses administering cancer chemotherapy in rural and remote areas of Queensland." Cancer Forum. 25 (1), pp. 17-19.
Pain management skills of regional nurses caring for older people with dementia: a needs analysis
Neville, Christine, McCarthy, Alexandra and Laurent, Kathryn. 2006. "Pain management skills of regional nurses caring for older people with dementia: a needs analysis." Collegian: The Australian Journal of Nursing Practice, Scholarship and Research. 13 (2), pp. 31-36.
Health issues for people in rural and remote areas
Rogers-Clark, Cath and McCarthy, Alexandra. 2005. "Health issues for people in rural and remote areas." Rogers-Clark, Cath, McCarthy, Alexandra and Martin-McDonald, Kristine (ed.) Living with illness: psychosocial challenges for nursing. Sydney, Australia. Elsevier. pp. 83-96
Job satisfaction and nurses in rural Australia
Hegney, Desley and McCarthy, Alexandra. 2000. "Job satisfaction and nurses in rural Australia." Journal of Nursing Administration. 30 (7-8), pp. 347 - 350.
The perceptions of rural nurses towards role change within the context of organisational change
McCarthy, Alexandra, Hegney, Desley and Pearson, Alan. 2000. "The perceptions of rural nurses towards role change within the context of organisational change." Australian Journal of Advanced Nursing. 17 (4), pp. 21-28.
Effects of size of health service on scope of rural nursing practice
Hegney, Desley, McCarthy, Alexandra and Pearson, Alan. 1999. "Effects of size of health service on scope of rural nursing practice." Collegian: The Australian Journal of Nursing Practice, Scholarship and Research. 6 (4), pp. 21-26, 42. https://doi.org/10.1016/S1322-7696(08)60605-8
Evidence-based practice and rural nursing: a literature review
McCarthy, A. and Hegney, D.. 1998. "Evidence-based practice and rural nursing: a literature review." Australian Journal of Rural Health. 6 (2), pp. 96-99. https://doi.org/10.1111/j.1440-1584.1998.tb00291.x
An overview of a study into the role and function of the rural nurse in Australia
Hegney, Desley, Pearson, Alan and McCarthy, Alexandra. 1997. An overview of a study into the role and function of the rural nurse in Australia. Adelaide, Australia. University of Adelaide.
The role and function of the rural nurse in Australia
Hegney, Desley, Pearson, Alan and McCarthy, Alexandra. 1997. The role and function of the rural nurse in Australia. Melbourne, Australia. Royal College of Nursing, Australia.
Remote and rural palliative care
McCarthy, Alexandra and Hegney, Desley. 1999. "Remote and rural palliative care." Aranda, Sanchia and O'Connor, Margaret (ed.) Palliative care nursing: a guide to practice. Melbourne, Australia. AUSMED Publications. pp. 83-101
Experiences of regional and rural people with cancer being treated with radiotherapy in a metropolitan centre
Martin-McDonald, Kristine, Rogers-Clark, Cath, Hegney, Desley, McCarthy, Alexandra and Pearce, Susanne. 2003. "Experiences of regional and rural people with cancer being treated with radiotherapy in a metropolitan centre." International Journal of Nursing Practice. 9 (3), pp. 176-182. https://doi.org/10.1046/j.1440-172X.2003.00421.x
Why nurses are attracted to rural and remote practice
Hegney, Desley, McCarthy, Alexandra, Rogers-Clark, Cath and Gorman, Don. 2002. "Why nurses are attracted to rural and remote practice." Australian Journal of Rural Health. 10 (3), pp. 178-186.
Why nurses are resigning from rural and remote Queensland health facilities
Hegney, Desley, McCarthy, Alexandra, Rogers-Clark, Cath and Gorman, Don. 2002. "Why nurses are resigning from rural and remote Queensland health facilities." Collegian: The Australian Journal of Nursing Practice, Scholarship and Research. 9 (2), pp. 33-39.
Retaining rural and remote area nurses: the Queensland Australia experience
Hegney, Desley, McCarthy, Alexandra, Rogers-Clark, Cath and Gorman, Don. 2002. "Retaining rural and remote area nurses: the Queensland Australia experience." Journal of Nursing Administration. 32 (3), pp. 128-135.
The interface of acute and aged care: the role of the nurse in a provincial area
Hegney, Desley, McCarthy, Alexandra, De La Rue, Mary Beth, Gorman, Don, Martin-McDonald, Kris, Fahey, Paul and Pretty, Grace. 2003. "The interface of acute and aged care: the role of the nurse in a provincial area." Australasian Journal on Ageing. 22 (2), pp. 85-90. https://doi.org/10.1111/j.1741-6612.2003.tb00472.x