A potential material for tissue engineering: silkworm silk/PLA biocomposite
Article
Article Title | A potential material for tissue engineering: silkworm silk/PLA biocomposite |
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ERA Journal ID | 4883 |
Article Category | Article |
Authors | Cheung, Hoi-Yan (Author), Lau, Kin-tak (Author), Tao, Xiao-Ming (Author) and Hui, David (Author) |
Journal Title | Composites Part B: Engineering |
Journal Citation | 39 (6), pp. 1026-1033 |
Number of Pages | 8 |
Year | 2008 |
Publisher | Elsevier |
Place of Publication | Oxford, United Kingdom |
ISSN | 1359-8368 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.compositesb.2007.11.009 |
Web Address (URL) | http://www.sciencedirect.com/science/article/pii/S1359836808000048 |
Abstract | Poly(lactic acid) (PLA), a kind of well recognized biodegradable polymer, was reinforced by silkworm silk fibers to form a completely biodegradable and biocompatible biocomposite for tissue engineering applications. The influence on the mechanical and thermal properties of the biocomposite in relation to the length and weight content of silk fibers is studied in this paper. Through the micro-hardness test, optimized fiber length and weight content of silk fibers used to make a better strength silk fiber/PLA biocomposite was determined. Tensile property test and thermal analyses including differential scanning calorimetry (DSC), dynamic mechanical analysis (DMA) and thermogravimetry analysis (TGA) for the silk fiber/PLA biocomposite with specified fiber length and weight content were then conducted to investigate its property changes in comparison to a pristine PLA sample. Experimentally, it was found that the fiber length and weight content of silk fibers are key parameters that would substantially influence the hardness of the biocomposite samples. For microscopic observations, good wettability of the fibers inside the biocomposite was seen. The surface of the fibers was well bonded with the matrix, as observed by a SEM image of fractured sample. As a result, it was found that the use of silk fibers can be a good candidate, as reinforcements for the development of polymeric scaffolds for tissue engineering applications. |
Keywords | bio composites; differential scanning calorimetry (photo-DSC); dynamic mechanical analysis (DMTA); fibre lengths; key parameters; mechanical and thermal properties; micro-hardness; microscopic observations; poly(d ,1-lactic acid) (PLA); polymeric scaffolds; potential materials; SEM imaging; silk fibres; strength (IGC: D5/D6); tissue engineering applications; weight content |
ANZSRC Field of Research 2020 | 320606. Regenerative medicine (incl. stem cells) |
400302. Biomaterials | |
401609. Polymers and plastics | |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | Hong Kong Polytechnic University, China |
University of New Orleans, United States | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q0q76/a-potential-material-for-tissue-engineering-silkworm-silk-pla-biocomposite
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