Austrocolorone B and Austrocolorin B1, cytotoxic anthracenone dimers from the Tasmanian mushroom Cortinarius vinosipes Gasparini
Article
Article Title | Austrocolorone B and Austrocolorin B1, cytotoxic anthracenone dimers from the Tasmanian mushroom Cortinarius vinosipes Gasparini |
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ERA Journal ID | 1602 |
Article Category | Article |
Authors | Beattie, Karren D. (Author), Thompson, Dion R. (Author), Tiralongo, Evelin (Author), Ratkowsky, David (Author), May, Tom W. (Author) and Gill, Melvyn (Author) |
Journal Title | Tetrahedron Letters: the international journal for the rapid publication of all preliminary communications in organic chemistry |
Journal Citation | 52 (42), pp. 5448-5451 |
Number of Pages | 4 |
Year | 2011 |
Place of Publication | Kidlington, OX. United Kingdom |
ISSN | 0040-4039 |
1873-3581 | |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.tetlet.2011.08.015 |
Abstract | The yellow dihydroanthracenone dimer, austrocolorin B1 and the unique violet-red 1,4-anthraquinone dimer, austrocolorone B, were isolated from the Tasmanian mushroom Cortinarius vinosipes and their structures and stereochemistry were determined from spectroscopic data. Austrocolorin B1 and austrocolorone B were found to exhibit potent cytotoxic activity in vitro against the murine lymphoblast (P388D1) cell line with IC50 values in the range 10–31 lg/mL. |
Keywords | Cytotoxic; Anthraquinone; Tricolorin; Australian fungi |
ANZSRC Field of Research 2020 | 340399. Macromolecular and materials chemistry not elsewhere classified |
340401. Biologically active molecules | |
340502. Natural products and bioactive compounds | |
321105. Chemotherapy | |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | University of Melbourne |
Southern Cross University | |
Griffith University | |
University of Tasmania | |
Royal Botanic Gardens, Melbourne, Australia | |
Institution of Origin | University of Southern Queensland |
Funding source | Australian Research Council (ARC) |
https://research.usq.edu.au/item/q28q5/austrocolorone-b-and-austrocolorin-b1-cytotoxic-anthracenone-dimers-from-the-tasmanian-mushroom-cortinarius-vinosipes-gasparini
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