321401. Basic pharmacology
| Title | 321401. Basic pharmacology |
|---|---|
| Parent | 3214. Pharmacology and pharmaceutical sciences |
Latest research outputs
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Clinical trials using functional foods provide unique challenges
Brown, Lindsay, Caligiuri, Stephanie P. B., Brown, Dan and Pierce, Grant N.. 2018. "Clinical trials using functional foods provide unique challenges." Journal of Functional Foods. 45, pp. 233-238. https://doi.org/10.1016/j.jff.2018.01.024Article
Alteration in the liver metabolome of rats with metabolic syndrome after treatment with Hydroxytyrosol. A Mass Spectrometry and Nuclear Magnetic Resonance - based metabolomics study
Dagla, Ioanna, Benaki, Dimitra, Baira, Eirini, Lemonakis, Nikolaoa, Poudyal, Hemant, Brown, Lindsay, Tsarbopoulos, Anthony, Skaltsounis, Alexios-Leandros, Mikros, Emmanouel and Gikas, Evagelos. 2018. "Alteration in the liver metabolome of rats with metabolic syndrome after treatment with Hydroxytyrosol. A Mass Spectrometry and Nuclear Magnetic Resonance - based metabolomics study." Talanta. 178, pp. 246-257. https://doi.org/10.1016/j.talanta.2017.09.029Article
Adenine-induced chronic kidney disease in rats
Diwan, Vishal, Brown, Lindsay and Gobe, Glenda C.. 2018. "Adenine-induced chronic kidney disease in rats." Nephrology. 23 (1), pp. 5-11. https://doi.org/10.1111/nep.13180Article
Coconut products improve signs of diet-induced metabolic syndrome in rats
Panchal, Sunil K., Carnahan, Sharyn and Brown, Lindsay. 2017. "Coconut products improve signs of diet-induced metabolic syndrome in rats." Plant Foods for Human Nutrition. 72 (4), pp. 418-424. https://doi.org/10.1007/s11130-017-0643-0Article
Beetroot and sodium nitrate ameliorate cardiometabolic changes in diet-induced obese hypertensive rats
Bhaswant, Maharshi, Brown, Lindsay, McAinch, Andrew J. and Mathai, Michael L.. 2017. "Beetroot and sodium nitrate ameliorate cardiometabolic changes in diet-induced obese hypertensive rats." Molecular Nutrition and Food Research. 61 (12), pp. 1-10. https://doi.org/10.1002/mnfr.201700478Article
Obesity-associated metabolic syndrome spontaneously induces infiltration of pro-inflammatory macrophage in synovium and promotes osteoarthritis
Sun, Antonia RuJia, Panchal, Sunil K., Friis, Thor, Sekar, Sunderajhan, Crawford, Ross, Brown, Lindsay, Xiao, Yin and Prasadam, Indira. 2017. "Obesity-associated metabolic syndrome spontaneously induces infiltration of pro-inflammatory macrophage in synovium and promotes osteoarthritis." PLoS One. 12 (8), pp. 1-22. https://doi.org/10.1371/journal.pone.0183693Article
The LC-MS-based metabolomics of hydroxytyrosol administration in rats reveals amelioration of the metabolic syndrome
Lemonakis, Nikolaos, Poudyal, Hemant, Halabalaki, Maria, Brown, Lindsay, Tsarbopoulos, Anthony, Skaltsounis, Alexios-Leandros and Gikas, Evagelos. 2017. "The LC-MS-based metabolomics of hydroxytyrosol administration in rats reveals amelioration of the metabolic syndrome." Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1041 (1041-1042), pp. 45-59. https://doi.org/10.1016/j.jchromb.2016.12.020Article
Inulin oligofructose attenuates metabolic syndrome in high-carbohydrate, high-fat diet-fed rats
Kumar, Senthil A., Ward, Leigh C. and Brown, Lindsay. 2016. "Inulin oligofructose attenuates metabolic syndrome in high-carbohydrate, high-fat diet-fed rats." The British Journal of Nutrition: an international journal of nutritional science. 116 (9), pp. 1502-1511. https://doi.org/10.1017/s0007114516003627Article
The flavonoid rutin improves kidney and heart structure and function in an adenine-induced rat model of chronic kidney disease
Diwan, Vishal, Brown, Lindsay and Gobe, Glenda C. 2017. "The flavonoid rutin improves kidney and heart structure and function in an adenine-induced rat model of chronic kidney disease." Journal of Functional Foods. 33, pp. 85-93. https://doi.org/10.1016/j.jff.2017.03.012Article
Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats
Bhaswant, Maharshi, Shafie, Siti Raihanah, Mathai, Michael L., Mouatt, Peter and Brown, Lindsay. 2017. "Anthocyanins in chokeberry and purple maize attenuate diet-induced metabolic syndrome in rats." Nutrition. 41, pp. 24-31. https://doi.org/10.1016/j.nut.2016.12.009Article
Saturated fatty acids induce development of both metabolic syndrome and osteoarthritis in rats
Sekar, Sunderajhan, Shafie, Siti Raihanah, Prasadam, Indira, Crawford, Ross, Panchal, Sunil K., Brown, Lindsay and Xiao, Yin. 2017. "Saturated fatty acids induce development of both metabolic syndrome and osteoarthritis in rats." Scientific Reports. 7. https://doi.org/10.1038/srep46457Article
Hydroxytyrosol ameliorates metabolic, cardiovascular and liver changes in a rat model of diet-induced metabolic syndrome: pharmacological and metabolism-based investigation
Poudyal, Hemant, Lemonakis, Nikolaos, Efentakis, Panagiotis, Gikas, Evangelos, Halabalaki, Maria, Andreadou, Ioanna, Skaltsounis, Leandros and Brown, Lindsay. 2017. "Hydroxytyrosol ameliorates metabolic, cardiovascular and liver changes in a rat model of diet-induced metabolic syndrome: pharmacological and metabolism-based investigation." Pharmacological Research. 117, pp. 32-45. https://doi.org/10.1016/j.phrs.2016.12.002Article
Linseed as a functional food for the management of obesity
Shafie, Siti Raihanah, Poudyal, Hemant, Panchal, Sunil K. and Brown, Lindsay. 2016. "Linseed as a functional food for the management of obesity." Hegde, Mahabaleshwar V., Zanwar, Anand Arvind and Adekar, Sharad P. (ed.) Omega-3 fatty acids: keys to nutritional health. Switzerland. Springer. pp. 173-187Edited book (chapter)
Selenium, vanadium, and chromium as micronutrients to improve metabolic syndrome
Panchal, Sunil K., Wanyonyi, Stephen and Brown, Lindsay. 2017. "Selenium, vanadium, and chromium as micronutrients to improve metabolic syndrome." Current Hypertension Reports. 19 (3), pp. 10-20. https://doi.org/10.1007/s11906-017-0701-xArticle
Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo
Konstantopoulos, Nicky, Molero, Juan C., McGee, Sean L., Spolding, Briana, Connor, Tim, de Vries, Melissa, Wanyonyi, Stephen, Fahey, Richard, Morrison, Shona, Swinton, Courtney, Jones, Sharon, Cooper, Adrian, Garcia-Guerra, Lucia, Foletta, Victoria C., Krippner, Guy, Andrikopoulos, Sofianos and Walder, Ken R.. 2012. "Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo." Diabetes. 61 (8), pp. 2146-2154. https://doi.org/10.2337/db11-0578Article
The tammar wallaby: a marsupial model to examine the timed delivery and role of bioactives in milk
Sharp, Julie A., Wanyonyi, Stephen, Modepalli, Vengama, Watt, Ashalyn, Kuruppath, Sanjana, Hinds, Lyn A., Kumar, Amit, Abud, Helen E., Lefevre, Christophe and Nicholas, Kevin R.. 2017. "The tammar wallaby: a marsupial model to examine the timed delivery and role of bioactives in milk." General and Comparative Endocrinology. 244, pp. 164-177. https://doi.org/10.1016/j.ygcen.2016.08.007Article
Anti-inflammatory γ- and δ-tocotrienols improve cardiovascular, liver and metabolic function in diet-induced obese rats
Wong, Weng-Yew, Ward, Leigh C., Fong, Chee Wai, Yap, Wei Ney and Brown, Lindsay. 2017. "Anti-inflammatory γ- and δ-tocotrienols improve cardiovascular, liver and metabolic function in diet-induced obese rats." European Journal of Nutrition. 56 (1), pp. 133-150. https://doi.org/10.1007/s00394-015-1064-1Article
Nutrient and immune sensing are obligate pathways in metabolism, immunity, and disease
Iyer, Abishek, Brown, Lindsay, Whitehead, Jonathan P., Prins, Johannes B. and Fairlie, David P.. 2015. "Nutrient and immune sensing are obligate pathways in metabolism, immunity, and disease." The FASEB Journal. 29 (9), pp. 3612-25. https://doi.org/10.1096/fj.15-271155Article
Modulation of tissue fatty acids by l-carnitine attenuates metabolic syndrome in diet-induced obese rats
Panchal, Sunil K., Poudyal, Hemant, Ward, Leigh C., Waanders, Jennifer and Brown, Lindsay. 2015. "Modulation of tissue fatty acids by l-carnitine attenuates metabolic syndrome in diet-induced obese rats." Food and Function. 6 (8), pp. 2496-2506. https://doi.org/10.1039/C5FO00480BArticle
Cyanidin 3-glucoside improves diet-induced metabolic syndrome in rats
Bhaswant, Maharshi, Fanning, Kent, Netzel, Michael, Mathai, Michael L., Panchal, Sunil K. and Brown, Lindsay. 2015. "Cyanidin 3-glucoside improves diet-induced metabolic syndrome in rats." Pharmacological Research. 102, pp. 208-217. https://doi.org/10.1016/j.phrs.2015.10.006Article
Green and black cardamom in a diet-induced rat model of metabolic syndrome
Bhaswant, Maharshi, Poudyal, Hemant, Mathai, Michael L., Ward, Leigh C., Mouatt, Peter and Brown, Lindsay. 2015. "Green and black cardamom in a diet-induced rat model of metabolic syndrome." Nutrients. 7 (9), pp. 7691-7707. https://doi.org/10.3390/nu7095360Article
Mechanisms of enhanced insulin secretion and sensitivity with n-3 unsaturated fatty acids
Bhaswant, Maharshi, Poudyal, Hemant and Brown, Lindsay. 2015. "Mechanisms of enhanced insulin secretion and sensitivity with n-3 unsaturated fatty acids." Journal of Nutritional Biochemistry. 26 (6), pp. 571-584. https://doi.org/10.1016/j.jnutbio.2015.02.001Article
Mechanism of the anti-hypertensive property of the naturally occurring phenolic, malabaricone C in DOCA-salt rats
Rathee, Jitesh S., Patro, Birija S., Brown, Lindsay and Chattopadhyay, Subrata. 2016. "Mechanism of the anti-hypertensive property of the naturally occurring phenolic, malabaricone C in DOCA-salt rats." Free Radical Research. 50 (1), pp. 111-121. https://doi.org/10.3109/10715762.2015.1112005Article
Functional foods as potential therapeutic options for metabolic syndrome
Brown, L., Poudyal, H. and Panchal, S. K.. 2015. "Functional foods as potential therapeutic options for metabolic syndrome." Obesity Reviews. 16 (11), pp. 914-941. https://doi.org/10.1111/obr.12313Article
Should the pharmacological actions of dietary fatty acids in cardio-metabolic disorders be classified based on biological or chemical function?
Poudyal, Hemant and Brown, Lindsay. 2015. "Should the pharmacological actions of dietary fatty acids in cardio-metabolic disorders be classified based on biological or chemical function?" Progress in Lipid Research. 59, pp. 172-200. https://doi.org/10.1016/j.plipres.2015.07.002Article
Induction of metabolic syndrome by excess fructose consumption
Wong, Weng-Yew and Brown, Lindsay. 2014. "Induction of metabolic syndrome by excess fructose consumption." Turan, Belma and Dhalla, Naranjan S. (ed.) Diabetic cardiomyopathy: biochemical and molecular mechanisms. New York, NY. United States. Springer. pp. 41-63Edited book (chapter)
A green algae mixture of Scenedesmus and Schroederiella attenuates obesity-linked metabolic syndrome in rats
Kumar, Senthil Arun, Magnusson, Marie, Ward, Leigh C., Paul, Nicholas A. and Brown, Lindsay. 2015. "A green algae mixture of Scenedesmus and Schroederiella attenuates obesity-linked metabolic syndrome in rats." Nutrients. 7 (4), pp. 2771-2787. https://doi.org/10.3390/nu7042771Article
Prebiotics in obesity
Carnahan, S., Balzer, A., Panchal, S. K. and Brown, L.. 2014. "Prebiotics in obesity." Panminerva Medica. 56 (2), pp. 165-175.Article
Increased progression to kidney fibrosis after erythropoietin is used as a treatment for acute kidney injury
Gobe, Glenda C., Bennett, Nigel C., West, Malcolm, Colditz, Paul, Brown, Lindsay, Vesey, David A. and Johnson, David W.. 2014. "Increased progression to kidney fibrosis after erythropoietin is used as a treatment for acute kidney injury." American Journal of Physiology: Renal Physiology. 306 (6), pp. F681-F692. https://doi.org/10.1152/ajprenal.00241.2013Article
Seaweed supplements normalise metabolic, cardiovascular and liver responses in high-carbohydrate, high-fat fed rats
Kumar, Senthil Arun, Magnusson, Marie, Ward, Leigh C., Paul, Nicholas A. and Brown, Lindsay. 2015. "Seaweed supplements normalise metabolic, cardiovascular and liver responses in high-carbohydrate, high-fat fed rats." Marine Drugs. 13 (2), pp. 788-805. https://doi.org/10.3390/md13020788Article
Obesity and metabolic syndrome
Panchal, Sunil K., Bhaswant, Maharshu and Brown, Lindsay. 2014. "Obesity and metabolic syndrome." Vela, Jose M., Maldonado, Rafael and Hamon, Michel (ed.) In vivo models for drug discovery. Weinheim, Germany. John Wiley & Sons. pp. 333-348Edited book (chapter)
Food as medicine [Introduction]
Panchal, Sunil K., Ward, Leigh C. and Brown, Lindsay. 2013. "Food as medicine [Introduction]." Canadian Journal of Physiology and Pharmacology. 91 (6), pp. 503-503. https://doi.org/10.1139/cjpp-2013-0147Notes or commentaries
Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism
Lim, Junxian, Iyer, Abishek, Liu, Ligong, Suen, Jacky Y., Lohman, Rink-Jan, Seow, Vernon, Yau, Mei-Kwan, Brown, Lindsay and Fairlie, David P.. 2013. "Diet-induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism." The FASEB Journal. 27 (12), pp. 4757-4767. https://doi.org/10.1096/fj.13-232702Article
Chronic l-arginine treatment improves metabolic, cardiovascular and liver complications in diet-induced obesity in rats
Alam, Md. Ashraful, Kauter, Kathleen, Withers, Kerry, Sernia, Conrad and Brown, Lindsay. 2013. "Chronic l-arginine treatment improves metabolic, cardiovascular and liver complications in diet-induced obesity in rats." Food and Function. 4 (1), pp. 83-91. https://doi.org/10.1039/c2fo30096fArticle
Naringin improves diet-induced cardiovascular dysfunction and obesity in high carbohydrate, high fat diet-fed rats
Alam, Md. Ashraful, Kauter, Kathleen and Brown, Lindsay. 2013. "Naringin improves diet-induced cardiovascular dysfunction and obesity in high carbohydrate, high fat diet-fed rats." Nutrients. 5 (3), pp. 637-650. https://doi.org/10.3390/nu5030637Article
C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling
Lim, Junxian, Iyer, Abishek, Suen, Jacky Y., Seow, Vernon, Reid, Robert C., Brown, Lindsay and Fairlie, David P.. 2013. "C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling." The FASEB Journal. 27 (2), pp. 822-831. https://doi.org/10.1096/fj.12-220582Article
Ferulic acid improves cardiovascular and kidney structure and function in hypertensive rats
Alam, Md. Ashraful, Sernia, Conrad and Brown, Lindsay. 2013. "Ferulic acid improves cardiovascular and kidney structure and function in hypertensive rats." Journal of Cardiovascular Pharmacology. 61 (3), pp. 240-249. https://doi.org/10.1097/FJC.0b013e31827cb600Article
Traditional Indian medicines for metabolic syndrome
Diwan, Vishal, Poudyal, Hemant and Brown, Lindsay. 2012. "Traditional Indian medicines for metabolic syndrome." Essa, M. Mohamed, Manickavasagan, A. and Sukumar, E. (ed.) Natural products and their active compounds on disease prevention. Hauppauge, NY. United States . Nova Science Publishers. pp. 1-21Edited book (chapter)
Tocotrienols reverse cardiovascular, metabolic and liver changes in high carbohydrate, high fat diet-fed rats
Wong, Weng-Yew, Poudyal, Hemant, Ward, Leigh C. and Brown, Lindsay. 2012. "Tocotrienols reverse cardiovascular, metabolic and liver changes in high carbohydrate, high fat diet-fed rats." Nutrients. 4 (10), pp. 1527-1541. https://doi.org/10.3390/nu4101527Article
Coffee and caffeine attenuate symptoms of metabolic syndrome in diet-induced obese rats
Panchal, S. and Brown, L.. 2012. "Coffee and caffeine attenuate symptoms of metabolic syndrome in diet-induced obese rats." 2012 Australian & New Zealand Obesity Society Annual Scientific Meeting. New Zealand 01 Oct 2012 Netherlands. https://doi.org/10.1016/j.orcp.2012.08.039Presentation