Coconut products improve signs of diet-induced metabolic syndrome in rats
Article
Article Title | Coconut products improve signs of diet-induced metabolic syndrome in rats |
---|---|
ERA Journal ID | 211219 |
Article Category | Article |
Authors | Panchal, Sunil K. (Author), Carnahan, Sharyn (Author) and Brown, Lindsay (Author) |
Journal Title | Plant Foods for Human Nutrition |
Journal Citation | 72 (4), pp. 418-424 |
Number of Pages | 7 |
Year | 2017 |
Place of Publication | United States |
ISSN | 0921-9668 |
1573-9104 | |
Digital Object Identifier (DOI) | https://doi.org/10.1007/s11130-017-0643-0 |
Web Address (URL) | https://link.springer.com/article/10.1007/s11130-017-0643-0 |
Abstract | Increasing prevalence of obesity and metabolic syndrome warrants identification of potential therapeutic options for intervention. This study tested commercially available Virgin Coconut Oil and Coconut Nourish, as coconuts are rich sources of lauric and myristic acids. Male Wistar rats were fed either corn starch diet (C); high-carbohydrate, high-fat diet (H); high-carbohydrate, high-virgin coconut oil diet (HV); or high-carbohydrate, high-coconut Nourish diet (HN) for 16 weeks. Metabolic, liver, and cardiovascular health parameters were measured during and at the end of the study. Virgin coconut oil lowered body weight (C 386±8g, H 516±13g, HV 459±10g), blood glucose concentrations (C 4.2±0.1 mmol/L, H 5.4±0.2 mmol/L, HV 4.6±0.2 mmol/L), systolic blood pressure (C 127±5mmHg, H 149±4mmHg, HV 133±3mmHg,) and diastolic stiffness (C 25.0±1.7, H 31.4±1.2, HV 25.2±2.3,) with improved structure and function of the heart and liver. Coconut Nourish increased total body lean mass (C 255±10g, H 270±16g, HN 303±15g) and lowered plasma total cholesterol concentrations (C 1.6±0.2 mmol/L, H 1.7±0.1 mmol/L, HN 1.0±0.0 mmol/L), systolic blood pressure (C 127±5mmHg, H 149±4mmHg, HN 130±3mmHg) and diastolic stiffness (C 25.0±1.7, H 31.4±1.2, HN 26.5±1.0), improved structure and function of the heart and liver but increased plasma concentrations of triglycerides (C 0.3±0.1 mmol/L, H 1.1±0.4 mmol/L, HN 1.8±0.2 mmol/L) and non-esterified fatty acids (C 1.2±0.3 mmol/L, H 3.3±0.8 mmol/L, HN 5.6±0.4 mmol/L). Thus, the fiber and protein in coconut Nourish and the medium-chain saturated fatty acids in virgin coconut oil may improve cardiovascular and liver complications in obesity. |
Keywords | coconut; lauric acid; metabolic syndrome; obesity; saturated fatty acids |
ANZSRC Field of Research 2020 | 321004. Nutritional science |
321401. Basic pharmacology | |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | Institute for Agriculture and the Environment |
Centre for Health Research | |
School of Health and Wellbeing | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q4q9z/coconut-products-improve-signs-of-diet-induced-metabolic-syndrome-in-rats
569
total views9
total downloads1
views this month0
downloads this month