Resistance to ocular antibiotics: an overview
Article
Article Title | Resistance to ocular antibiotics: an overview |
---|---|
ERA Journal ID | 40013 |
Article Category | Article |
Authors | |
Author | Brown, Lindsay |
Journal Title | Clinical and Experimental Optometry |
Journal Citation | 90 (4), pp. 258-262 |
Number of Pages | 5 |
Year | 2007 |
Place of Publication | Melbourne, Australia |
ISSN | 0816-4622 |
1444-0938 | |
Digital Object Identifier (DOI) | https://doi.org/10.1111/j.1444-0938.2007.00154.x |
Abstract | The introduction of new antibiotic compounds into therapy initiates the development of resistance by the target bacteria. Resistance increases the risk of treatment failure with potentially serious consequences. Local application of antibacterial compounds to the eyes may lead to bacterial resistance in bacterial isolates from the eyes. The incidence of resistant strains of common pathogens is probably increasing. As compounds can be absorbed into the systemic circulation following ocular administration, the subsequent low concentrations in the blood could provide the selective pressure for the survival of resistant bacteria in the body. Despite this possibility, there are no reports of systemic resistance in bacteria following ocular administration of antibacterial compounds. All health-care professionals should be concerned about this possibility and continue to use these important compounds with respect. |
Keywords | anti-bacterial agents; bacterial physiology; drug resistance; eye infections, bacterial; humans |
ANZSRC Field of Research 2020 | 321201. Ophthalmology |
321405. Pharmaceutical sciences | |
320701. Medical bacteriology | |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | University of Queensland |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q0w43/resistance-to-ocular-antibiotics-an-overview
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