Queen Garnet plum juice and raspberry cordial in mildly hypertensive obese or overweight subjects: a randomized, double-blind study
Article
Article Title | Queen Garnet plum juice and raspberry cordial in mildly hypertensive obese or overweight subjects: a randomized, double-blind study |
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ERA Journal ID | 124610 |
Article Category | Article |
Authors | Bhaswant, Maharshi (Author), Brown, Lindsay (Author) and Mathai, Michael L. (Author) |
Journal Title | Journal of Functional Foods |
Journal Citation | 56, pp. 119-126 |
Number of Pages | 8 |
Year | 2019 |
Place of Publication | Netherlands |
ISSN | 1756-4646 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.jff.2019.03.011 |
Web Address (URL) | https://www.sciencedirect.com/science/article/pii/S1756464619301318 |
Abstract | The anthocyanin, cyanidin 3-glucoside, in Queen Garnet (QG) plums reduced cardiovascular parameters, obesity and inflammation in diet-induced metabolic syndrome in rats. We have now assessed whether QG juice improves cardiovascular and metabolic risk factors and markers of inflammation in mildly hypertensive overweight or obese humans. The 32 subjects were randomly divided into two groups consuming either QG juice or Placebo (raspberry cordial) drinks for 12 weeks. QG juice decreased systolic blood pressure by 12 ± 3 mmHg, diastolic blood pressure by 9 ± 2 mmHg, insulin by 6 ± 3 pmol/L, and leptin by 4 ± 2.5 ng/ml, and increased adiponectin by 3.62 ± 0.28 µg/ml. Cyanidin 3-glucoside is the likely active component of the plum juice, with possible additive effects of other flavonoids such as quercetin glycosides. Thus, QG juice decreased blood pressure and attenuated some risk factors of metabolic syndrome after 12 weeks suggesting that daily consumption could attenuate the development of cardiovascular and metabolic diseases. |
Keywords | Queen Garnet plum; Anthocyanins; Cyanidin 3-glucoside; hypertension; obesity |
ANZSRC Field of Research 2020 | 321004. Nutritional science |
321401. Basic pharmacology | |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | Victoria University |
School of Health and Wellbeing | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q5336/queen-garnet-plum-juice-and-raspberry-cordial-in-mildly-hypertensive-obese-or-overweight-subjects-a-randomized-double-blind-study
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