Bone mineral density (BMD) in rats in a model of metabolic syndrome (METS)
Poster
Paper/Presentation Title | Bone mineral density (BMD) in rats in a model of metabolic syndrome (METS) |
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Presentation Type | Poster |
Authors | Ward, L. C. (Author), Panchal, S. K. (Author), Bhaswant, M. (Author), Wong, W.-Y. (Author), Poudyal, H. (Author) and Brown, L. (Author) |
Journal or Proceedings Title | Journal of Nutrition & Intermediary Metabolism: Proceedings of the Nutrition Society of Australia 38th Annual Scientific Meeting |
Journal Citation | 1, p. 51 |
Number of Pages | 1 |
Year | 2014 |
Place of Publication | Netherlands |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.jnim.2014.10.191 |
Web Address (URL) of Paper | http://www.sciencedirect.com/science/article/pii/S2352385914001923 |
Conference/Event | Nutrition Society of Australia 38th Annual Scientific Meeting |
Event Details | Nutrition Society of Australia 38th Annual Scientific Meeting Event Date 01 Dec 2014 Event Location Hobart, Tasmania |
Abstract | Background/Aims: Studies assessing association between MetS and bone status have yielded inconsistent results; subjects with MetS had lower bone mineral density (BMD) but also lower fracture risk. We investigated BMD in an animal model of MetS and the effects of feeding a variety of different nutraceuticals. Methods: Male Wistar rats were fed on either a corn starch (CS) or highcarbohydrate, high-fat (HCHF) diet that produces physiological characteristics of MetS for 8 weeks followed by a further 8 weeks during which half of each group of rats received a dietary supplement of a nutraceutical (including cardamom, chia, inulin, lignan, linseed oil, caffeine, seaweeds; n ¼ 8-15 per group, n ¼ 194 control diet). BMD of rats was determined at 16 weeks using dual energy x-ray absorptiometry (Norland XR36). Difference between groups was tested using two-way ANOVA; factors, diet and nutraceutical. Results:Rats fed the HCHF diet were significantly heavier than those fed on the CS diet (474.5 ± 4.3 vs. 401.7 ± 4.3 g, p < 0.0001 respectively) but control HCHF Conclusions: An HCHF (MetS) diet increased overall BMD due to a larger body mass but decreased BMD relative to body weight; partly offset by supplementation with chia seeds, chokeberry or inulin. |
ANZSRC Field of Research 2020 | 321004. Nutritional science |
321401. Basic pharmacology | |
Public Notes | Abstract only published - made accessible according to License. |
Byline Affiliations | University of Queensland |
Institute for Agriculture and the Environment | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q4z2v/bone-mineral-density-bmd-in-rats-in-a-model-of-metabolic-syndrome-mets
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