The influence of Wasabi (Wasabia Japonica) on diet-induced metabolic syndrome in Wistar rats

Poster

Thomaz, Fernanda, Panchal, Sunil, Worrall, Simon and Ward, Leigh. 2016. "The influence of Wasabi (Wasabia Japonica) on diet-induced metabolic syndrome in Wistar rats." 38th ESPEN Congress. Copenhagen, Denmark 17 - 20 Sep 2016 Amsterdam, The Netherlands. https://doi.org/10.1016/S0261-5614(16)30559-3
Paper/Presentation Title

The influence of Wasabi (Wasabia Japonica) on diet-induced metabolic syndrome in Wistar rats

Presentation TypePoster
AuthorsThomaz, Fernanda (Author), Panchal, Sunil (Author), Worrall, Simon (Author) and Ward, Leigh (Author)
Journal or Proceedings TitleClinical Nutrition: Abstracts of the 38th ESPEN Congress
Journal Citation35 (1 (Supplement)), p. S124
Article NumberSUN-P216
Number of Pages1
Year2016
Place of PublicationAmsterdam, The Netherlands
Digital Object Identifier (DOI)https://doi.org/10.1016/S0261-5614(16)30559-3
Conference/Event38th ESPEN Congress
Event Details
38th ESPEN Congress
Event Date
17 to end of 20 Sep 2016
Event Location
Copenhagen, Denmark
Abstract

Rationale: Metabolic syndrome (MetS) has reached a prevalence of ∼24% worldwide. Plant sourced foods such as wasabi have been shown to be effective therapeutic agents in inflammation, obesity and chronic diseases. The present study aims to investigate the influence of Wasabia japonica on the body composition, blood pressure, blood glucose and lipid profile of Wistar rats with high-fat high carbohydrate (HFHC) diet-induced MetS.

Methods: Rats were fed either a corn starch (CS) or high-fat high-carbohydrate (HFHC) diet for 8 weeks. After this period, CS (n = 12/group) and HFHC rats (n = 12/group) were treated with 5% of Wasabia japonica for 8 weeks. Animals had adlibitum access to food and water. Metabolic parameters including systolic blood pressure (SBP), basal blood glucose, dual-energy X-ray absorptiometry (DXA) and plasma lipid analysis were measured during and after the 8-week protocol.

Results: CS rats showed less fat mass and basal blood glucose levels compared to the control rats, whereas rats fed with 5% of wasabi in HFHC diet decreased approximately 10% of systolic blood pressure (p < 0.05). However, both CS and HFHC groups had no significant difference in abdominal circumference and lipid profile.

Conclusion: This 8-week trial suggests that wasabi exerted an ameliorative effect in some parameters of MetS such as hypertension, glycaemia and obesity, which might be attributable to lipolytic effects of wasabi in adipose tissues. These findings suggest that Wasabia japonica has potential applications as an additional therapy to the conventional approaches provided to individuals with MetS.

ANZSRC Field of Research 2020321004. Nutritional science
321401. Basic pharmacology
Public Notes

Abstract only published. © 2016 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
This journal and the individual contributions
contained in it are protected by the copyright of
Elsevier Ltd and European Society for Clinical
Nutrition and Metabolism.

Byline AffiliationsUniversity of Queensland
Institute for Agriculture and the Environment
Institution of OriginUniversity of Southern Queensland
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