Green coffee ameliorates components of diet-induced metabolic syndrome in rats
Article
Article Title | Green coffee ameliorates components of diet-induced metabolic syndrome in rats |
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ERA Journal ID | 124610 |
Article Category | Article |
Authors | Bhandarkar, Nikhil S. (Author), Mouatt, Peter (Author), Brown, Lindsay (Author) and Panchal, Sunil K. (Author) |
Journal Title | Journal of Functional Foods |
Journal Citation | 57, pp. 141-149 |
Number of Pages | 9 |
Year | 2019 |
Place of Publication | Netherlands |
ISSN | 1756-4646 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.jff.2019.04.003 |
Web Address (URL) | https://www.sciencedirect.com/science/article/pii/S1756464619301811 |
Abstract | Metabolic syndrome, especially obesity, increases the risk of type 2 diabetes and cardiovascular disease. We hypothesised that green coffee will attenuate metabolic, cardiovascular and liver parameters in high-carbohydrate high-fat diet-fed rats. Male Wistar rats (8–9 weeks old) were divided into 6 groups and fed for 16 weeks with either corn starch diet (C), C with either 5% green or decaffeinated green coffee in food for the last 8 weeks, high-carbohydrate high-fat diet (H) or H with either 5% green or decaffeinated green coffee in food for the last 8 weeks. Green coffee contained chlorogenic acids, trigonelline, caffeine and diterpenoids; decaffeinated green coffee contained these compounds but no caffeine. Green coffee attenuated body weight, systolic blood pressure, inflammation in the heart and liver and diastolic stiffness without improving glucose sensitivity or plasma lipids. We suggest that chlorogenic acids, trigonelline and diterpenoids in green coffee attenuate diet-induced abnormalities in heart and liver. |
Keywords | green coffee; obesity; metabolic syndrome; high-carbohydrate, high-fat diet; cardiovascular disease |
ANZSRC Field of Research 2020 | 321004. Nutritional science |
321401. Basic pharmacology | |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | School of Health and Wellbeing |
Southern Cross University | |
Functional Foods Research Group | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q5562/green-coffee-ameliorates-components-of-diet-induced-metabolic-syndrome-in-rats
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