Oral nutritional supplements for preventing surgical site infections: protocol for a systematic review and meta-analysis
Article
Article Title | Oral nutritional supplements for preventing surgical site infections: protocol for a systematic review and meta-analysis |
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ERA Journal ID | 201547 |
Article Category | Article |
Authors | Ralph, Nicholas (Author), Brown, Lindsay (Author), McKillop, Kristy L. (Author), Duff, Jed (Author), Osborne, Sonya (Author), Terry, Victoria R. (Author), Edward, Karen-Leigh (Author), King, Rachel (Author) and Barui, Edward (Author) |
Journal Title | Systematic Reviews |
Journal Citation | 9, pp. 1-10 |
Article Number | 37 |
Number of Pages | 10 |
Year | 2020 |
Publisher | BioMed Central Ltd. |
Place of Publication | United Kingdom |
ISSN | 2046-4053 |
Digital Object Identifier (DOI) | https://doi.org/10.1186/s13643-020-01293-x |
Web Address (URL) | https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-020-01293-x |
Abstract | Background: Surgical site infections (SSIs) are among the most common healthcare-associated infections. Under- nutrition is an important risk factor for SSIs and can lead to delayed wound healing and longer hospital stays. Oral nutritional supplements are prescribed to reduce the risk of infection and improve health status, but data from randomised controlled trials (RCTs) have shown mixed results. Thus, the objective of our planned systematic review is to evaluate oral nutritional supplements on preventing SSIs in adult surgical patients Methods: RCTs conducted in adult surgical patients who receive oral nutritional support will be included. The primary outcome will be the incidence of SSIs (within 30 days of surgery or within 90 days for joint replacement surgery). Secondary outcomes will be changes in nutritional status, mortality, health-related quality of life and costs. Literature searches will be conducted in several electronic databases (from inception onwards): MEDLINE, Embase, CINAHL and The Cochrane Central Register of Controlled Trials (CENTRAL). Grey literature will be identified through searching clinical trial registers and dissertation databases. Two reviewers will independently screen all citations, full-text articles and abstract data. The study methodological quality (or bias) will be appraised using the Cochrane risk of bias tool. If feasible, we will conduct random effects meta-analysis where appropriate. Discussion: This systematic review will evaluate the evidence for pre- and post-surgical intervention with oral nutritional supplements in adults. Findings from this planned review may inform subsequent nutritional interventions for hospitalised patients who undergo surgery. |
Keywords | Surgical site infection; Malnutrition; Nutrition; Surgery |
ANZSRC Field of Research 2020 | 420501. Acute care |
Byline Affiliations | School of Nursing and Midwifery |
School of Health and Wellbeing | |
St Vincent's Private Hospital, Toowoomba, Australia | |
University of Newcastle | |
Queensland University of Technology | |
Swinburne University of Technology | |
School of Sciences | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q5w2z/oral-nutritional-supplements-for-preventing-surgical-site-infections-protocol-for-a-systematic-review-and-meta-analysis
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