Influence of a specialized Trigonella foenum-graecum seed extract (Libifem), on testosterone, estradiol and sexual function in healthy menstruating women, a randomised placebo controlled study
Article
Article Title | Influence of a specialized Trigonella foenum-graecum seed extract (Libifem), on testosterone, estradiol and sexual function in healthy menstruating women, a randomised placebo controlled study |
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ERA Journal ID | 14852 |
Article Category | Article |
Authors | Rao, Amanda (Author), Steels, Elizabeth (Author), Beccaria, Gavin (Author), Inder, Warrick (Author) and Vitetta, Luis (Author) |
Journal Title | Phytotherapy Research |
Journal Citation | 29 (8), pp. 1123-1130 |
Number of Pages | 8 |
Year | 2015 |
Place of Publication | United Kingdom |
ISSN | 0951-418X |
1099-1573 | |
Digital Object Identifier (DOI) | https://doi.org/10.1002/ptr.5355 |
Web Address (URL) | http://onlinelibrary.wiley.com/doi/10.1002/ptr.5355/full |
Abstract | The aim of the study was to evaluate the effect of Trigonella foenum-graecum (fenugreek) seed extract on sex hormones and sexual function in healthy menstruating women who reported low sexual drive. This short term, single site, double blind, randomised, placebo-controlled study was conducted on 80 women, aged 20 to 49 years. Participants were randomised to either an oral dose of a standardised T. foenum-graecum seed extract (libifem) at a dose of 600 mg/day or placebo over two menstrual cycles. Dehydroepiandrosterone sulfate, progesterone, androstenedione, total and free testosterone, estradiol (E2), luteinizing hormone, follicle stimulating hormone, sex hormone binding globulin and cholesterol were measured at baseline and 8 weeks. The individual aspects of sexual function were measured using the Derogatis interview for sexual functioning and female sexual function index self-administered questionnaires. Stress, fatigue and quality of the relationship with partner were also measured using the PSS (Perceived Stress Scale), MFI-20 (Multidimensional Fatigue Inventory) and DAS (Dyadic Adjustment Scale) quality of life measures, respectively. There was a significant increase in free testosterone and E2 in the active group as well as sexual desire and arousal compared with the placebo group. The results indicate that this extract of T. foenum-graecum may be a useful treatment for increasing sexual arousal and desire in women. Copyright © 2015 John Wiley & Sons, Ltd. |
Keywords | Trigonella foenum-graecum; fenugreek; oestrogen; estradiol; testosterone; sexual desire; sexual function |
Contains Sensitive Content | Does not contain sensitive content |
ANZSRC Field of Research 2020 | 420802. Naturopathy |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | University of Sydney |
Integrated Health Group, Australia | |
School of Psychology and Counselling | |
University of Queensland | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q345y/influence-of-a-specialized-trigonella-foenum-graecum-seed-extract-libifem-on-testosterone-estradiol-and-sexual-function-in-healthy-menstruating-women-a-randomised-placebo-controlled-study
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