Functional Foods Research Group: Stephen Wanyonyi

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Wanyonyi, Stephen. Functional Foods Research Group: Stephen Wanyonyi. Toowoomba. https://doi.org/10.26192/2z6r-wx03
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Functional Foods Research Group: Stephen Wanyonyi

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Obesity as part of metabolic syndrome is a major lifestyle disorder throughout the world. Current drug treatments for obesity produce small and usually unsustainable decreases in body weight with the risk of major adverse effects. Surgery has been the only treatment producing successful long-term weight loss. As a different but complementary approach, lifestyle modification including the use of functional foods could produce a reliable decrease in obesity with decreased comorbidities. Our research includes functional foods such as berries, vegetables, fibre-enriched grains and beverages such as tea and coffee. Our studies also focus on development of animal models of inflammatory diseases such inflammatory bowel disease, chronic kidney disease and arthritis. These models are then used to investigate the effects of functional foods in attenuation of these disorders.

Research Involvement
Is owned byWanyonyi, Stephen
Physical Storage Location
USQ Toowoomba

Toowoomba

Digital Object Identifier (DOI)https://doi.org/10.26192/2z6r-wx03
ANZSRC Field of Research 2020321401. Basic pharmacology
Institution of OriginUniversity of Southern Queensland
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https://research.usq.edu.au/item/q650x/functional-foods-research-group-stephen-wanyonyi

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Saskatoon Berry Amelanchier alnifolia Regulates Glucose Metabolism and Improves Cardiovascular and Liver Signs of Diet-Induced Metabolic Syndrome in Rats
du Preez, Ryan, Wanyonyi, Stephen, Mouatt, Peter, Panchal, Sunil K. and Brown, Lindsay. 2020. "Saskatoon Berry Amelanchier alnifolia Regulates Glucose Metabolism and Improves Cardiovascular and Liver Signs of Diet-Induced Metabolic Syndrome in Rats." Nutrients. 12 (4), pp. 1-16. https://doi.org/10.3390/nu12040931
Linseed components are more effective than whole linseed in reversing diet-induced metabolic syndrome in rats
Shafie, Siti Raihanah, Wanyonyi, Stephen, Panchal, Sunil K. and Brown, Lindsay. 2019. "Linseed components are more effective than whole linseed in reversing diet-induced metabolic syndrome in rats." Nutrients. 11 (1677), pp. 1-16. https://doi.org/10.3390/nu11071677
Achacha (Garcinia humilis) Rind Improves Cardiovascular Function in Rats with Diet-Induced Metabolic Syndrome
John, Oliver D., Wanyonyi, Stephen, Mouatt, Peter, Panchal, Sunil K. and Brown, Lindsay. 2018. "Achacha (Garcinia humilis) Rind Improves Cardiovascular Function in Rats with Diet-Induced Metabolic Syndrome." Nutrients. 10 (10), pp. 1-15. https://doi.org/10.3390/nu10101425
Kappaphycus alvarezii as a food supplement prevents diet-induced metabolic syndrome in rats
Wanyonyi, Stephen, du Preez, Ryan, Brown, Lindsay, Paul, Nicholas A. and Panchal, Sunil K.. 2017. "Kappaphycus alvarezii as a food supplement prevents diet-induced metabolic syndrome in rats." Nutrients. 9 (11). https://doi.org/10.3390/nu9111261
The comparative genomics of monotremes, marsupials, and pinnipeds: models to examine the functions of milk proteins
Sharp, Julie A., Watt, Ashalyn, Bisana, Swathi, Modepalli, Vengama, Wanyonyi, Stephen, Kumar, Amit, Kwek, Joly, Collins, Rod, Lefevre, Christopher and Nicholas, Kevin R.. 2014. "The comparative genomics of monotremes, marsupials, and pinnipeds: models to examine the functions of milk proteins ." Singh, Harjinder, Boland, Mike and Thompson, Abby (ed.) Milk proteins: from expression to food. Amsterdam, The Netherlands. Elsevier. pp. 75-112
Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity
Su, Hua, Gunter, Jennifer H., de Vries, Melissa, Connor, Tim, Wanyonyi, Stephen, Newell, Felicity S., Segal, David, Molero, Juan Carlos, Reizes, Ofer, Prins, Johannes B., Hutley, Louise J., Walder, Ken and Whitehead, Jonathan P.. 2009. "Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity." Biochemical and Biophysical Research Communications. 386 (2), pp. 351-355. https://doi.org/10.1016/j.bbrc.2009.06.040
Selenium, vanadium, and chromium as micronutrients to improve metabolic syndrome
Panchal, Sunil K., Wanyonyi, Stephen and Brown, Lindsay. 2017. "Selenium, vanadium, and chromium as micronutrients to improve metabolic syndrome." Current Hypertension Reports. 19 (3), pp. 10-20. https://doi.org/10.1007/s11906-017-0701-x
A gene expression signature for insulin resistance
Konstantopoulos, Nicky, Foletta, Victoria C., Segal, David H., Shields, Katherine A., Sanigorski, Andrew, Windmill, Kelly, Swinton, Courtney, Connor, Tim, Wanyonyi, Stephen, Dyer, Thomas D., Fahey, Richard P., Watt, Rose A., Curran, Joanne E., Molero, Juan C., Krippner, Guy, Collier, Greg R., James, David E., Blangero, John, Jowett, Jeremy B. and Walder, Ken R.. 2011. "A gene expression signature for insulin resistance." Physiological Genomics. 43 (3), pp. 110-120. https://doi.org/10.1152/physiolgenomics.00115.2010
Tammar wallaby mammary cathelicidins are differentially expressed during lactation and exhibit antimicrobial and cell proliferative activity
Wanyonyi, Stephen S., Sharp, Julie A., Khalil, Elie, Lefevre, Christophe and Nicholas, Kevin R.. 2011. "Tammar wallaby mammary cathelicidins are differentially expressed during lactation and exhibit antimicrobial and cell proliferative activity." Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology. 160 (3), pp. 431-439. https://doi.org/10.1016/j.cbpa.2011.07.015
Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo
Konstantopoulos, Nicky, Molero, Juan C., McGee, Sean L., Spolding, Briana, Connor, Tim, de Vries, Melissa, Wanyonyi, Stephen, Fahey, Richard, Morrison, Shona, Swinton, Courtney, Jones, Sharon, Cooper, Adrian, Garcia-Guerra, Lucia, Foletta, Victoria C., Krippner, Guy, Andrikopoulos, Sofianos and Walder, Ken R.. 2012. "Methazolamide is a new hepatic insulin sensitizer that lowers blood glucose in vivo." Diabetes. 61 (8), pp. 2146-2154. https://doi.org/10.2337/db11-0578
The tammar wallaby: a model system to examine domain-specific delivery of milk protein bioactives
Nicholas, Kevin, Sharp, Julie, Watt, Ashalyn, Wanyonyi, Stephen, Crowley, Tamsyn, Gillespie, Meagan and Lefevre, Christophe. 2012. "The tammar wallaby: a model system to examine domain-specific delivery of milk protein bioactives." Seminars in Cell and Developmental Biology. 23 (5), pp. 547-556. https://doi.org/10.1016/j.semcdb.2012.03.016
The extracellular matrix regulates MaeuCath1a gene expression
Wanyonyi, Stephen S., Lefevre, Christophe, Sharp, Julie A. and Nicholas, Kevin R.. 2013. "The extracellular matrix regulates MaeuCath1a gene expression." Developmental and Comparative Immunology. 40 (3-4), pp. 289-299. https://doi.org/10.1016/j.dci.2013.02.010
The extracellular matrix locally regulates asynchronous concurrent lactation in tammar wallaby (Macropus eugenii)
Wanyonyi, Stephen S., Lefevre, Christophe, Sharp, Julie A. and Nicholas, Kevin R.. 2013. "The extracellular matrix locally regulates asynchronous concurrent lactation in tammar wallaby (Macropus eugenii)." Matrix Biology. 32 (6), pp. 342-351. https://doi.org/10.1016/j.matbio.2013.02.001
The tammar wallaby: a marsupial model to examine the timed delivery and role of bioactives in milk
Sharp, Julie A., Wanyonyi, Stephen, Modepalli, Vengama, Watt, Ashalyn, Kuruppath, Sanjana, Hinds, Lyn A., Kumar, Amit, Abud, Helen E., Lefevre, Christophe and Nicholas, Kevin R.. 2017. "The tammar wallaby: a marsupial model to examine the timed delivery and role of bioactives in milk." General and Comparative Endocrinology. 244, pp. 164-177. https://doi.org/10.1016/j.ygcen.2016.08.007
Transcriptome analysis of mammary epithelial cell gene expression reveals novel roles of the extracellular matrix
Wanyonyi, Stephen S., Kumar, Amit, Du Preez, Ryan, Lefevre, Christophe and Nicholas, Kevin R.. 2017. "Transcriptome analysis of mammary epithelial cell gene expression reveals novel roles of the extracellular matrix." Biochemistry and Biophysics Reports. 12, pp. 120-128. https://doi.org/10.1016/j.bbrep.2017.08.013
Activation of the selenoprotein SEPS1 gene expression by pro-inflammatory cytokines in HepG2 cells
Gao, Yuan, Hannan, Nicholas R. F., Wanyonyi, Stephen, Konstantopolous, Nicky, Pagnon, Joanne, Feng, Helen C., Jowett, Jeremy B. M., Kim, Kee-Hong, Walder, Ken and Collier, Greg R.. 2006. "Activation of the selenoprotein SEPS1 gene expression by pro-inflammatory cytokines in HepG2 cells." Cytokine. 33 (5), pp. 246-251. https://doi.org/10.1016/j.cyto.2006.02.005