Expanded review criteria: the case of no pharmacological interventions in dementia

Article


Cohen-Mansfield, Jiska, Buckwalter, Kathleen, Beattie, Elizabeth, Rose, Karen, Neville, Christine and Kolanowski, Ann. 2014. "Expanded review criteria: the case of no pharmacological interventions in dementia." Journal of Alzheimer's Disease. 41, pp. 15-28. https://doi.org/10.3233/JAD-132357
Article Title

Expanded review criteria: the case of no pharmacological interventions in dementia

ERA Journal ID16300
Article CategoryArticle
AuthorsCohen-Mansfield, Jiska (Author), Buckwalter, Kathleen (Author), Beattie, Elizabeth (Author), Rose, Karen (Author), Neville, Christine (Author) and Kolanowski, Ann (Author)
Journal TitleJournal of Alzheimer's Disease
Journal Citation41, pp. 15-28
Number of Pages14
Year2014
Place of PublicationNetherlands
ISSN1387-2877
1875-8908
Digital Object Identifier (DOI)https://doi.org/10.3233/JAD-132357
Abstract

This paper challenges the assumptions underlying many reviews and offers alternative criteria for examining evidence for nonpharmacological interventions.We evaluated 27 reviews examining interventions for persons with dementia as they relate to the issues of selection based on randomized controlled trial (RCT) design. Reviews were described by type of intervention, level of cognitive function, and criteria for inclusion. Of the 27 reviews, 46% required RCTs for inclusion and most had stringent
inclusion criteria. This resulted in poor utilization of the literature and low ecological validity. Eliminating most of the available data poses a critical problem to clinical and research development. Studies meeting strict methodological criteria may not generalize to the greater population or may exclude sub-populations and interventions. Limitations of double-blind RCTs and potential design solutions are set forth based on appropriate populations, problems, interventions, and settings characteristics.

Keywordsdementia, interventions, older persons, randomized controlled trials, research designs, review
ANZSRC Field of Research 2020429999. Other health sciences not elsewhere classified
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Byline AffiliationsTel Aviv University, Israel
University of Iowa, United States
Queensland University of Technology
University of Virginia, United States
University of Queensland
Pennsylvania State University, United States
Institution of OriginUniversity of Southern Queensland
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