A novel spectral entropy-based index for assessing the depth of anaesthesia
Article
Article Title | A novel spectral entropy-based index for assessing the depth of anaesthesia |
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ERA Journal ID | 211938 |
Article Category | Article |
Authors | Ra, Jee Sook (Author), Li, Tianning (Author) and Li, Yan (Author) |
Journal Title | Brain Informatics |
Journal Citation | 8 (1) |
Article Number | 10 |
Number of Pages | 12 |
Year | 2021 |
Publisher | Springer |
Place of Publication | Germany |
ISSN | 2198-4018 |
2198-4026 | |
Digital Object Identifier (DOI) | https://doi.org/10.1186/s40708-021-00130-8 |
Web Address (URL) | https://braininformatics.springeropen.com/articles/10.1186/s40708-021-00130-8 |
Abstract | Anaesthesia is a state of temporary controlled loss of awareness induced for medical operations. An accurate assessment of the depth of anaesthesia (DoA) helps anesthesiologists to avoid awareness during surgery and keep the recovery period short. However, the existing DoA algorithms have limitations, such as not robust enough for different patients and having time delay in assessment. In this study, to develop a reliable DoA measurement method, pre-denoised electroencephalograph (EEG) signals are divided into ten frequency bands (α, β1, β2, β3, β4, β, βγ, γ, δ and θ), and the features are extracted from different frequency bands using spectral entropy (SE) methods. SE from the beta-gamma frequency band (21.5–38.5 Hz) and SE from the beta frequency band show the highest correlation (R-squared value: 0.8458 and 0.7312, respectively) with the most popular DoA index, bispectral index (BIS). In this research, a new DoA index is developed based on these two SE features for monitoring the DoA. The highest Pearson correlation coefficient by comparing the BIS index for testing data is 0.918, and the average is 0.80. In addition, the proposed index shows an earlier reaction than the BIS index when the patient goes from deep anaesthesia to moderate anaesthesia, which means it is more suitable for the real-time DoA assessment. In the case of poor signal quality (SQ), while the BIS index exhibits inflexibility with cases of poor SQ, the new proposed index shows reliable assessment results that reflect the clinical observations. |
Keywords | spectral entropy; EEG; depth of anaesthesia; machine learning; linear regression |
Contains Sensitive Content | Does not contain sensitive content |
ANZSRC Field of Research 2020 | 460207. Modelling and simulation |
429999. Other health sciences not elsewhere classified | |
320999. Neurosciences not elsewhere classified | |
Byline Affiliations | School of Sciences |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q675v/a-novel-spectral-entropy-based-index-for-assessing-the-depth-of-anaesthesia
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