Cardiovascular Risk Assessment in Hemodialysis Patients
Article
Article Title | Cardiovascular Risk Assessment in Hemodialysis Patients |
---|---|
Article Category | Article |
Authors | Pokhrel, Asmita (Author), Pokhrel, Buddhi Raj (Author), Gyawali, Prajwal (Author), Regmi, Deepak (Author), Khanal, Madhav (Author), Bhattarai, Ashim (Author), Poudel, Prakash (Author) and KC, Anuj (Author) |
Journal Title | Nepal Medical College Journal |
Journal Citation | 23 (3), pp. 252-258 |
Number of Pages | 7 |
Year | 2021 |
Publisher | Nepal Medical College |
Place of Publication | Nepal |
ISSN | 2676-1319 |
2676-1424 | |
Digital Object Identifier (DOI) | https://doi.org/10.3126/nmcj.v23i3.40385 |
Web Address (URL) | https://www.nepjol.info/index.php/nmcj/article/view/40385 |
Abstract | Cardiovascular diseases are the leading cause of death in hemodialysis patients. We aimed to evaluate non-traditional cardiovascular risk factors: homocysteine, high sensitive C-reactive protein, oxidized LDL antibodies, phosphate, and red cell distribution width in chronic kidney disease patients under maintenance hemodialysis along with traditional cardiovascular risk factors like age, hypertension, diabetes mellitus, among others. A total of 78 diagnosed chronic kidney disease patients under maintenance hemodialysis visiting a tertiary care center were included in the study, of which 59% were male. Hyperhomocysteinemia was present in 79.5% of the participants, with the median homocysteine level being 28.43 µmol/L. The median hsCRP level was 4.74 mg/L, and 59% and 24.4% of the total participants were at high and moderate cardiovascular risk respectively. The median oxidized LDL antibody level was 4235 U/mL, which is within the reference range. The median red cell distribution width was 14.05%, which is within the normal range. Left ventricular hypertrophy, a common cardiovascular disease in such patients, was found in 55.13% of the participants. Serum homocysteine level was significantly higher in patients with left ventricular hypertrophy, whereas serum C- reactive protein level was |
Keywords | Hemodialysis; Homocysteine; high sensitive C-reactive protein; oxidized LDL antibody; Red cell distribution width |
Contains Sensitive Content | Does not contain sensitive content |
ANZSRC Field of Research 2020 | 320101. Cardiology (incl. cardiovascular diseases) |
320214. Nephrology and urology | |
Byline Affiliations | Nepal Medical College and Teaching Hospital |
Universal College of Medical Sciences and Teaching Hospital, Nepal | |
University of Newcastle | |
Institute of Medicine, Nepal | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q6vyx/cardiovascular-risk-assessment-in-hemodialysis-patients
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Cardiovascular Risk Assessment in Hemodialysis Patients.pdf | ||
License: CC BY 4.0 | ||
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