Whole blood viscosity is associated with baseline cerebral perfusion in acute ischemic stroke

Article


Gyawali, Prajwal, Lillicrap, Thomas Patrick, Tomari, Shinya, Bivard, Andrew, Holliday, Elizabeth, Parsons, Mark, Levi, Christopher, Garcia-Esperon, Carlos and Spratt, Neil. 2022. "Whole blood viscosity is associated with baseline cerebral perfusion in acute ischemic stroke." Neurological Sciences. 43 (4), pp. 2375-2381. https://doi.org/10.1007/s10072-021-05666-5
Article Title

Whole blood viscosity is associated with baseline cerebral perfusion in acute ischemic stroke

ERA Journal ID16652
Article CategoryArticle
AuthorsGyawali, Prajwal (Author), Lillicrap, Thomas Patrick (Author), Tomari, Shinya (Author), Bivard, Andrew (Author), Holliday, Elizabeth (Author), Parsons, Mark (Author), Levi, Christopher (Author), Garcia-Esperon, Carlos (Author) and Spratt, Neil (Author)
Journal TitleNeurological Sciences
Journal Citation43 (4), pp. 2375-2381
Number of Pages7
Year2022
Place of PublicationItaly
ISSN1590-1874
1590-3478
Digital Object Identifier (DOI)https://doi.org/10.1007/s10072-021-05666-5
Web Address (URL)https://link.springer.com/article/10.1007/s10072-021-05666-5
Abstract

Whole blood viscosity (WBV) is the intrinsic resistance to flow developed due to the frictional force between adjacent layers of flowing blood. Elevated WBV is an independent risk factor for stroke. Poor microcirculation due to elevated WBV can prevent adequate perfusion of the brain and might act as an important secondary factor for hypoperfusion in acute ischaemic stroke. In the present study, we examined the association of WBV with basal cerebral perfusion assessed by CT perfusion in acute ischaemic stroke. Confirmed acute ischemic stroke patients (n = 82) presenting in hours were recruited from the single centre. Patients underwent baseline multimodal CT (non-contrast CT, CT angiography and CT perfusion). Where clinically warranted, patients also underwent follow-up DWI. WBV was measured in duplicate within 2 h after sampling from 5-mL EDTA blood sample. WBV was significantly correlated with CT perfusion parameters such as perfusion lesion volume, ischemic core volume and mismatch ratio; DWI volume and baseline NIHSS. In a multivariate linear regression model, WBV significantly predicted acute perfusion lesion volume, core volume and mismatch ratio after adjusting for the effect of occlusion site and collateral status. Association of WBV with hypoperfusion (increased perfusion lesion volume, ischaemic core volume and mismatch ratio) suggest the role of erythrocyte rheology in cerebral haemodynamic of acute ischemic stroke. The present findings open new possibilities for therapeutic strategies targeting erythrocyte rheology to improve cerebral microcirculation in stroke.

Keywordswhole blood viscosity, stroke, CT Perfusion
ANZSRC Field of Research 2020320905. Neurology and neuromuscular diseases
Byline AffiliationsSchool of Health and Wellbeing
Hunter Medical Research Institute, Australia
University of Newcastle
Department of Health, New South Wales
Institution of OriginUniversity of Southern Queensland
Permalink -

https://research.usq.edu.au/item/q6v68/whole-blood-viscosity-is-associated-with-baseline-cerebral-perfusion-in-acute-ischemic-stroke

Download files


Published Version
  • 121
    total views
  • 44
    total downloads
  • 2
    views this month
  • 2
    downloads this month

Export as

Related outputs

Changes in Haematological Parameters and Lipid Profiles in Diabetes Mellitus: A Literature Review
Mbah, Jovita I., Bwititi, Phillip T., Gyawali, Prajwal and Nwose, Ezekiel U.. 2024. "Changes in Haematological Parameters and Lipid Profiles in Diabetes Mellitus: A Literature Review." Cureus: Journal of Medical Science. 16 (7). https://doi.org/10.7759/cureus.64201
Blood Viscosity Changes in Diabetes Mellitus: A 20-Year Bibliometric Review and Future Directions
Mbah, Jovita I., Bwititi, Phillip T., Gyawali, Prajwal and Nwose, Ezekiel U.. 2024. "Blood Viscosity Changes in Diabetes Mellitus: A 20-Year Bibliometric Review and Future Directions." Cureus: Journal of Medical Science. 16 (7). https://doi.org/10.7759/cureus.64211
Association Between E-Cigarettes, Cognition and Mood in Adolescents
Novak, Marissa L., Gyawali, Prajwal and Wang, Grace. 2024. "Association Between E-Cigarettes, Cognition and Mood in Adolescents ." Substance Use and Misuse. https://doi.org/10.1080/10826084.2024.2383597
Photoperiod and metabolic health: evidence, mechanism, and implications
Regmi, Prashant, Young, Morag, Minigo, Gabriela, Milic, Natalie and Gyawali, Prajwal. 2024. "Photoperiod and metabolic health: evidence, mechanism, and implications." Metabolism: clinical and experimental. 152. https://doi.org/10.1016/j.metabol.2023.155770
Whole Blood Viscosity and Cerebral Blood Flow in Acute Ischemic Stroke
Gyawali, Prajwal, Lillicrap, Thomas P., Garcia-Esperon, Carlos G., Bhattarai, Aseem, Bivard, Andrew and Spratt, Neil. 2024. "Whole Blood Viscosity and Cerebral Blood Flow in Acute Ischemic Stroke." Seminars in Thrombosis and Hemostasis. 50 (4), pp. 580-591. https://doi.org/10.1055/s-0043-1775858
An Evaluation of Community Health Workers’ Knowledge, Attitude and Personal Lifestyle Behaviour in Non-Communicable Disease Health Promotion and Their Association with Self-Efficacy and NCD-Risk Perception
Yenit, Melaku Kindie, Kolbe-Alexander, Tracy L., Gelaye, Kassahun Alemu, Gezie, Lemma Derseh, Tesema, Getayeneh Antehunegn, Abebe, Solomon Mekonnen, Azale, Telake, Shitu, Kegnie and Gyawali, Prajwal. 2023. "An Evaluation of Community Health Workers’ Knowledge, Attitude and Personal Lifestyle Behaviour in Non-Communicable Disease Health Promotion and Their Association with Self-Efficacy and NCD-Risk Perception." International Journal of Environmental Research and Public Health. 20 (9). https://doi.org/10.3390/ijerph20095642
Editorial: Stress, mood, and fatigue: Tackling “invisible” obstacles in stroke rehabilitation and recovery
Gyawali, Prajwal, Wong, Dana, Hordacre, Brenton, Ong, Lin Kooi and English, Coralie. 2023. "Editorial: Stress, mood, and fatigue: Tackling “invisible” obstacles in stroke rehabilitation and recovery ." Frontiers in Neurology. 13. https://doi.org/10.3389/fneur.2022.1121667
Drug-Resistant Tuberculosis Stigma Among HealthCare Workers Toward the Development of a Stigma-Reduction Strategy: A Scoping Review
Aranas, Lolita Liboon, Alam, Khorshed, Gyawali, Prajwal and Mahumud, Rashidul Mahumud. 2023. "Drug-Resistant Tuberculosis Stigma Among HealthCare Workers Toward the Development of a Stigma-Reduction Strategy: A Scoping Review." Inquiry: the Journal of Health Care Organization Provision and Financing. 60, pp. 1-10. https://doi.org/10.1177/00469580231180754
Scoping review of molecular biomarkers associated with fatigue, stress, and depression in stroke survivors: A protocol
Potter, Tarynn, Gange, Nisal, Whiteside, Eliza and Gyawali, Prajwal. 2023. "Scoping review of molecular biomarkers associated with fatigue, stress, and depression in stroke survivors: A protocol." PLoS One. 18. https://doi.org/10.1371/journal.pone.0281238.
Examining Drug-Resistant Tuberculosis Stigma Among Health Care Workers Toward the Development of a Stigma-Reduction Intervention: Protocol for a Scoping Review
Aranas, Lolita Liboon, Alam, Khorshed, Gyawali, Prajwal and Mahumud, Rashidul Alam. 2023. "Examining Drug-Resistant Tuberculosis Stigma Among Health Care Workers Toward the Development of a Stigma-Reduction Intervention: Protocol for a Scoping Review ." JMIR Research Protocols. 12, p. e43084. https://doi.org/10.2196/43084
Successful health promotion, its challenges and the way forward in Nepal
Dhital, Madhu Koirala, Dhital, Shalik Ram, KC, Bhakta Bahadur, Owens, Vicki, Khadka, Hem Raj and Gyawali, Prajwal. 2022. "Successful health promotion, its challenges and the way forward in Nepal." Global Health Promotion. 30 (1), pp. 68-71. https://doi.org/10.1177/17579759221117792
Psychological Stress Management and Stress Reduction Strategies for Stroke Survivors: A Scoping Review
Hinwood, Madeleine, Ilicic, Marina, Gyawali, Prajwal, Coupland, Kirsten, Kluge, Murielle G., Smith, Angela, Bowden, Sue, Nilsson, Michael and Walker, Frederick Rohan. 2023. "Psychological Stress Management and Stress Reduction Strategies for Stroke Survivors: A Scoping Review." Annals of Behavioral Medicine. 57 (2), p. 111–130. https://doi.org/10.1093/abm/kaac002
Exploring the relationship between fatigue and circulating levels of the pro-inflammatory biomarkers interleukin-6 and C-reactive protein in the chronic stage of stroke recovery: a cross-sectional study
Gyawali, Prajwal, Hinwood, Madeleine, Chow, Wei Zhen, Kluge, Murielle, Ong, Lin Kooi, Nilsson, Michael and Walker, Frederick Rohan. 2020. "Exploring the relationship between fatigue and circulating levels of the pro-inflammatory biomarkers interleukin-6 and C-reactive protein in the chronic stage of stroke recovery: a cross-sectional study." Brain, Behavior, & Immunity - Health. 9, pp. 1-6. https://doi.org/10.1016/j.bbih.2020.100157
Prevalence, Trends, and Correlates of Joint Patterns of Aerobic and Muscle-Strengthening Activity and Sleep Duration: A Pooled Analysis of 359,019 Adults in the National Health Interview Survey 2004-2018
Oftedal, Stina, Holliday, Elizabeth G., Reynolds, Amy C., Bennie, Jason A., Kline, Christopher E. and Duncan, Mitch J.. 2022. "Prevalence, Trends, and Correlates of Joint Patterns of Aerobic and Muscle-Strengthening Activity and Sleep Duration: A Pooled Analysis of 359,019 Adults in the National Health Interview Survey 2004-2018." Journal of Physical Activity and Health. 19 (4), pp. 246-255. https://doi.org/10.1123/jpah.2021-0682
Dyslipidemia among Patients with Ischemic Stroke in the Department of Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study
Baral, Sushil, Pokhrel, Asmita, Kumar B.K., Shyam, Kshetri, Rupesh, Regmi, Prashant and Gyawali, Prajwal. 2022. "Dyslipidemia among Patients with Ischemic Stroke in the Department of Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study." Journal of the Nepal Medical Association. 60 (250), pp. 511-516. https://doi.org/10.31729/jnma.7491
Address an unmet need: establishing the prevalence of metabolic syndrome in Darling Down region
Gardiner, P., Aung, N., Ng, L., Stolic, S., Bliss, E., Gyawali, P. and Roberts, M.. 2022. "Address an unmet need: establishing the prevalence of metabolic syndrome in Darling Down region." Toowoomba, Darling Downs Health Services Research Symposium.
Cardiovascular Risk Assessment in Hemodialysis Patients
Pokhrel, Asmita, Pokhrel, Buddhi Raj, Gyawali, Prajwal, Regmi, Deepak, Khanal, Madhav, Bhattarai, Ashim, Poudel, Prakash and KC, Anuj. 2021. "Cardiovascular Risk Assessment in Hemodialysis Patients." Nepal Medical College Journal. 23 (3), pp. 252-258. https://doi.org/10.3126/nmcj.v23i3.40385
Role of purinergic signalling in endothelial dysfunction and thrombo-inflammation in ischaemic stroke and cerebral small vessel disease
Lee, Natasha Ting, Ong, Lin Kooi, Gyawali, Prajwal, Nassir, Che Mohd Nasril Che Mohd, Mustapha, Muzaimi, Nandurkar, Harshal H. and Sashindranath, Maithili. 2021. "Role of purinergic signalling in endothelial dysfunction and thrombo-inflammation in ischaemic stroke and cerebral small vessel disease." Biomolecules. 11 (7). https://doi.org/10.3390/biom11070994
Acute Effects of Frequent Light-Intensity Standing-Based Exercises That Interrupt 8 Hours of Prolonged Sitting on Postprandial Glucose in Stroke Survivors: A Dose-Escalation Trial
Mackie, Paul, Crowfoot, Gary, Gyawali, Prajwal, Janssen, Heidi, Holliday, Elizabeth, Dunstan, David and English, Coralie. 2021. "Acute Effects of Frequent Light-Intensity Standing-Based Exercises That Interrupt 8 Hours of Prolonged Sitting on Postprandial Glucose in Stroke Survivors: A Dose-Escalation Trial." Journal of Physical Activity and Health. 18 (6), pp. 644-652. https://doi.org/10.1123/jpah.2020-0516
Time-efficient intervention to improve older adolescents’ cardiorespiratory fitness: findings from the ‘Burn 2 Learn’ cluster randomised controlled trial
Lubans, David R., Smith, Jordan J., Eather, Narelle, Leahy, Angus A., Morgan, Philip J., Lonsdale, Chris, Plotnikoff, Roland C., Nilsson, Michael, Kennedy, Sarah G., Holliday, Elizabeth G., Weaver, Natasha, Noetel, Michael, Shigeta, Tatsuya T., Mavilidi, Myrto F., Valkenborghs, Sarah R., Gyawali, Prajwal, Walker, Frederick R., Costigan, Sarah A. and Hillman, Charles H.. 2020. "Time-efficient intervention to improve older adolescents’ cardiorespiratory fitness: findings from the ‘Burn 2 Learn’ cluster randomised controlled trial." British Journal of Sports Medicine. https://doi.org/10.1136/bjsports-2020-103277
Similar cognitive deficits in mice and humans in the chronic phase post-stroke identified using the touchscreen-based paired-associate learning task
Chow, Wei Zhen, Ong, Lin Kooi, Kluge, Murielle G., Gyawali, Prajwal, Walker, Frederick R. and Nilsson, Michael. 2020. "Similar cognitive deficits in mice and humans in the chronic phase post-stroke identified using the touchscreen-based paired-associate learning task." Scientific Reports. 10, pp. 1-8. https://doi.org/10.1038/s41598-020-76560-x
Plasmin Generation Potential and Recanalization in Acute Ischaemic Stroke; an Observational Cohort Study of Stroke Biobank Samples
Lillicrap, Thomas, Keragala, Charithani B., Draxler, Dominik F., Chan, Jilly, Ho, Heidi, Harman, Stevi, Niego, Be’eri, Holliday, Elizabeth, Levi, Christopher R., Garcia-Esperon, Carlos, Spratt, Neil, Gyawali, Prajwal, Bivard, Andrew, Parsons, Mark W., Montaner, Joan, Bustamante, Alejandro, Cadenas, Israel Fernandez, Cloud, Geoffrey, Maguire, Jane M., ..., Medcalf, Robert L.. 2020. "Plasmin Generation Potential and Recanalization in Acute Ischaemic Stroke; an Observational Cohort Study of Stroke Biobank Samples." Frontiers in Neurology. 11, pp. 1-4. https://doi.org/10.3389/fneur.2020.589628
Prevalence of cardiovascular risk factors among chronic kidney disease patients undergoing hemodialysis in a tertiary care center, Kathmandu, Nepal
Pokhrel, A., Gyawali, P., Pokhrel, B. R., Khanal, M. P., Manandhar, D. N., Bwititi, P. and Nwose, E. U.. 2019. "Prevalence of cardiovascular risk factors among chronic kidney disease patients undergoing hemodialysis in a tertiary care center, Kathmandu, Nepal." Nepal Medical College Journal. 21 (4), pp. 313-318. https://doi.org/10.3126/nmcj.v21i4.27629
Accuracy of glucose meter among adults in a semi-urban area in Kathmandu, Nepal
Pokhrel, Asmita, Silvanus, Vinutha, Pokhrel, Buddhi Raj, Baral, Binaya, Khanal, Madhav, Gyawali, Prajwal, Pokhrel, Laxman and Regmi, Deepak. 2019. "Accuracy of glucose meter among adults in a semi-urban area in Kathmandu, Nepal." Nepal Medical Association Journal. 57 (216), pp. 104-108. https://doi.org/10.31729/jnma.4247
Hemorheological parameters better classify metabolic syndrome than novel cardiovascular risk factors and peripheral vascular disease marker
Gyawali, Prajwal, Richards, Ross S., Tinley, Paul, Nwose, Ezekiel Uba and Bwititi, Phillip T.. 2016. "Hemorheological parameters better classify metabolic syndrome than novel cardiovascular risk factors and peripheral vascular disease marker." Clinical Hemorheology and Microcirculation. 64 (1), pp. 1-5. https://doi.org/10.3233/CH-152033
Prediabetes and cardiovascular complications study (PACCS): international collaboration 4 years' summary and future direction
Nwose, E. U., Richards, R. S., Bwititi, P. T., Igumbor, E. O., Oshionwu, E. J., Okolie, K., Onyia, I. C., Pokhrel, A., Gyawali, P., Okuzor, J. N., Oguoma, V. M., Gardiner, F. W. and Wang, L.. 2017. "Prediabetes and cardiovascular complications study (PACCS): international collaboration 4 years' summary and future direction." BMC Research Notes. 10 (1). https://doi.org/10.1186/s13104-017-3017-7
Current research on cigarette toxicity: critical appraisal in view of clinical laboratory
Gyawali, Prajwal and Oguoma, Victor Maduabuchi. 2016. "Current research on cigarette toxicity: critical appraisal in view of clinical laboratory." International Journal of Research in Medical Sciences. 4 (6), pp. 1785-1793. https://doi.org/10.18203/2320-6012.ijrms20161725
School-based physical activity intervention for older adolescents: rationale and study protocol for the Burn 2 Learn cluster randomised controlled trial
Leahy, Angus A, Eather, Narelle, Smith, Jordan J, Hillman, Charles, Morgan, Philip J, Nilsson, Michael, Lonsdale, Chris, Plotnikoff, Ronald C, Noetel, Michael, Holliday, Elizabeth, Shigeta, Tatsuya T, Costigan, Sarah A, Walker, Frederick R, Young, Sarah, Valkenborghs, Sarah R, Gyawali, Prajwal, Harris, Nigel, Kennedy, Sarah G and Lubans, David R. 2019. "School-based physical activity intervention for older adolescents: rationale and study protocol for the Burn 2 Learn cluster randomised controlled trial." BMJ Open. 9 (5). https://doi.org/10.1136/bmjopen-2018-026029
Exploration of stress management interventions to address psychological stress in stroke survivors: A protocol for a scoping review
Hinwood, Madeleine, Ilicic, Marina, Gyawali, Prajwal, Kluge, Murielle Gabriela, Coupland, Kirsten, Smith, Angela, Nilsson, Michael and Walker, Frederick Rohan. 2020. "Exploration of stress management interventions to address psychological stress in stroke survivors: A protocol for a scoping review." BMJ Open. 10 (3). https://doi.org/10.1136/bmjopen-2019-035592
Opposing associations of stress and resilience with functional outcomes in stroke survivors in the chronic phase of stroke: A cross-sectional study
Gyawali, Prajwal, Chow, Wei Zhen, Hinwood, Madeleine, Kluge, Murielle, English, Coralie, Ong, Lin Kooi, Nilsson, Michael and Walker, Frederick Rohan. 2020. "Opposing associations of stress and resilience with functional outcomes in stroke survivors in the chronic phase of stroke: A cross-sectional study." Frontiers in Neurology. 11, pp. 1-12. https://doi.org/10.3389/fneur.2020.00230
Cardiovascular risk screening options in diabetes: framework for selective adoption
Nwose, Ezekiel U., Digban, Kester A., Oshionwu, Echinei J., Onyia, Innocent C., Bwititi, Phillip T., Oguoma, Victor M., Anyasodor, Anayochukwu E. and Gyawali, Prajwal. 2016. "Cardiovascular risk screening options in diabetes: framework for selective adoption." National Journal of Community Medicine. 7 (6), pp. 540-544.
Comparison of lipid profile parameters and oxidized low-density lipoprotein between normal and preeclamptic pregnancies in a tertiary care hospital in Nepal
Timalsina, Santosh, Gyawali, Prajwal and Bhattarai, Aseem. 2016. "Comparison of lipid profile parameters and oxidized low-density lipoprotein between normal and preeclamptic pregnancies in a tertiary care hospital in Nepal." International Journal of Women's Health. 8, pp. 627-631. https://doi.org/10.2147/IJWH.S117850
Quantitative Measurement of Erythrocyte Aggregation as a Systemic Inflammatory Marker by Ultrasound Imaging: A Systematic Review
Gyawali, Prajwal, Ziegler, Daniela, Cailhier, Jean-Franois, Denault, Andre and Cloutier, Guy. 2018. "Quantitative Measurement of Erythrocyte Aggregation as a Systemic Inflammatory Marker by Ultrasound Imaging: A Systematic Review." Ultrasound in Medicine and Biology. 44 (7), pp. 1303-1317. https://doi.org/10.1016/j.ultrasmedbio.2018.02.020
Frequent, short bouts of light-intensity exercises while standing decreases systolic blood pressure: Breaking Up Sitting Time after Stroke (BUST-Stroke) trial
English, Coralie, Janssen, Heidi, Crowfoot, Gary, Bourne, Josephine, Callister, Robin, Dunn, Ashlee, Oldmeadow, Christopher, Ong, Lin K., Palazzi, Kerrin, Patterson, Amanda, Spratt, Neil J., Walker, F. R., Dunstan, David W. and Bernhardt, Julie. 2018. "Frequent, short bouts of light-intensity exercises while standing decreases systolic blood pressure: Breaking Up Sitting Time after Stroke (BUST-Stroke) trial." International Journal of Stroke. 13 (9), pp. 932-940. https://doi.org/10.1177/1747493018798535
Breaking up sitting time after stroke (BUST-stroke)
English, Coralie, Janssen, Heidi, Crowfoot, Gary, Callister, Robin, Dunn, Ashlee, Mackie, Paul, Oldmeadow, Christopher, Ong, Lin K., Palazzi, Kerrin, Patterson, Amanda J., Spratt, Neil J., Walker, F. Rohan, Bernhardt, Julie and Dunstan, David W.. 2018. "Breaking up sitting time after stroke (BUST-stroke)." International Journal of Stroke. 13 (9), pp. 921-931. https://doi.org/10.1177/1747493018801222
Growth Hormone Deficiency Is Frequent After Recent Stroke
Lillicrap, Thomas, Garcia-Esperon, Carlos, Walker, Frederick Rohan, Ong, Lin Kooi, Nilsson, Michael, Spratt, Neil, Levi, Christopher R., Parsons, Mark, Isgaard, Jorgen and Bivard, Andrew. 2018. "Growth Hormone Deficiency Is Frequent After Recent Stroke." Frontiers in Neurology. 9, pp. 1-4. https://doi.org/10.3389/fneur.2018.00713
Growth Hormone Improves Cognitive Function After Experimental Stroke
Ong, Lin Kooi, Chow, Wei Zhen, TeBay, Clifford, Kluge, Murielle, Pietrogrande, Giovanni, Zalewska, Katarzyna, Crock, Patricia, Åberg, N. David, Bivard, Andrew, Johnson, Sarah J., Walker, Frederick R., Nilsson, Michael and Isgaard, Jorgen. 2018. "Growth Hormone Improves Cognitive Function After Experimental Stroke." Stroke. 49 (5), pp. 1257 - 1266. https://doi.org/10.1161/STROKEAHA.117.020557
Association of abnormal erythrocyte morphology with oxidative stress and inflammation in metabolic syndrome
Gyawali, Prajwal, Richards, Ross S., Bwititi, Phillip T. and Nwose, Ezekiel Uba. 2015. "Association of abnormal erythrocyte morphology with oxidative stress and inflammation in metabolic syndrome." Blood Cells, Molecules and Diseases. 54 (4), pp. 360-363. https://doi.org/10.1016/j.bcmd.2015.01.005
The association of dyslipidemia with erythrocyte aggregation
Gyawali, Prajwal, Richards, Ross S, Bwititi, Phillip T. and Nwose, Ezekiel Uba. 2015. "The association of dyslipidemia with erythrocyte aggregation ." Clinical Lipidology. 10 (2), pp. 129-135. https://doi.org/10.2217/CLP.15.3
Hemorheology, ankle brachial pressure index (ABPI) and toe brachial pressure index (TBPI) in metabolic syndrome
Gyawali, Prajwal, Richards, Ross S., Tinley, Paul and Nwose, Ezekiel Uba. 2014. "Hemorheology, ankle brachial pressure index (ABPI) and toe brachial pressure index (TBPI) in metabolic syndrome ." Microvascular Research. 95, pp. 31-36. https://doi.org/10.1016/j.mvr.2014.06.013
Product of serum calcium and phosphorus (Ca× PO4) as predictor of cardiovascular disease risk in predialysis patients
Regmi, Prashant, Malla, Bimala, Gyawali, Prajwal, Sigdel, Manoj, Shrestha, Rojeet, Shah, Dibya Singh and Khanal, Madhav Prasad. 2014. "Product of serum calcium and phosphorus (Ca× PO4) as predictor of cardiovascular disease risk in predialysis patients." Clinical Biochemistry. 47 (1-2), pp. 77-81. https://doi.org/10.1016/j.clinbiochem.2013.09.012
Erythrocyte aggregation and metabolic syndrome
Gyawali, Prajwal, Richards, Ross S., Hughes, Diane L. and Tinley, Paul. 2014. "Erythrocyte aggregation and metabolic syndrome." Clinical Hemorheology and Microcirculation. 57 (1), pp. 73-83. https://doi.org/10.3233/CH-131792
Whole-blood viscosity and metabolic syndrome
Gyawali, Prajwal, Richards, Ross S, Nwose, Ezekiel Uba and Bwititi, Phillip T. 2012. "Whole-blood viscosity and metabolic syndrome ." Clinical Lipidology. 7 (6), pp. 709-719. https://doi.org/10.2217/CLP.12.65
Erythrocyte morphology in metabolic syndrome
Gyawali, Prajwal, Richards, Ross S. and Nwose, Ezekiel Uba. 2012. "Erythrocyte morphology in metabolic syndrome ." Expert Review of Hematology. 5 (5), pp. 523-531. https://doi.org/10.1586/EHM.12.47