Breaking up sitting time after stroke (BUST-stroke)
Article
Article Title | Breaking up sitting time after stroke |
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ERA Journal ID | 35469 |
Article Category | Article |
Authors | English, Coralie, Janssen, Heidi, Crowfoot, Gary, Callister, Robin, Dunn, Ashlee, Mackie, Paul, Oldmeadow, Christopher, Ong, Lin K., Palazzi, Kerrin, Patterson, Amanda J., Spratt, Neil J., Walker, F. Rohan, Bernhardt, Julie and Dunstan, David W. |
Journal Title | International Journal of Stroke |
Journal Citation | 13 (9), pp. 921-931 |
Number of Pages | 11 |
Year | Dec 2018 |
Place of Publication | United Kingdom |
ISSN | 1747-4930 |
1747-4949 | |
Digital Object Identifier (DOI) | https://doi.org/10.1177/1747493018801222 |
Web Address (URL) | https://journals.sagepub.com/doi/10.1177/1747493018801222 |
Abstract | Objectives: People with stroke sit for long periods each day, which may compromise blood glucose control and increase risk of recurrent stroke. Studies in other populations have found regular activity breaks have a significant immediate (within-day) positive effect on glucose metabolism. We examined the effects of breaking up uninterrupted sitting with frequent, short bouts of light-intensity physical activity in people with stroke on post-prandial plasma glucose and insulin. Methods: Randomized within-participant crossover trial. We included people between 3 months and 10 years post-stroke, ambulant with minimal assistance and not taking diabetic medication other than metformin. The three experimental conditions (completed in random order) were: sitting for 8 h uninterrupted, sitting with 3 min bouts of light-intensity exercise while standing every 30 min, or sitting with 3 min of walking every 30 min. Meals were standardized and bloods were collected half- to one-hourly via an intravenous cannula. Results: A total of 19 participants (9 female, mean [SD] age 68.2 [10.2]) completed the trial. The majority (n = 12, 63%) had mild stroke symptoms (National Institutes of Stroke Scale score 0–13). There was no significant effect of experimental condition on glucose (mean [SD] positive incremental area [+iAUC] mmol·L·h-1 under the curve during sitting 42.3 [29.5], standing 47.4 [23.1], walking 44.6 [26.5], p = 0.563) or insulin (mean + iAUC pmol·L·h-1 sitting 14,161 [7,560], standing 14,043 [8,312], walking 14,008 [8,269], p = 0.987). Conclusion: Frequent, short bouts of light-intensity physical activity did not have a significant effect on post-prandial plasma glucose and insulin in this sample of people with stroke. Further studies are needed to identify strategies that improve inactivity-related glucose metabolism after stroke. |
Keywords | Sedentary behavior; physical activity; rehabilitation; secondary prevention |
ANZSRC Field of Research 2020 | 420109. Rehabilitation |
320903. Central nervous system | |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | University of Newcastle |
Florey Institute of Neuroscience, Australia | |
Hunter New England, Australia | |
Hunter Medical Research Institute, Australia | |
School of Health and Medical Sciences | |
Centre for Health Research | |
Baker Heart and Diabetes Institute, Australia | |
Australian Catholic University |
https://research.usq.edu.au/item/y8327/breaking-up-sitting-time-after-stroke-bust-stroke
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