Whole-blood viscosity and metabolic syndrome
Article
Article Title | Whole-blood viscosity and metabolic syndrome |
---|---|
ERA Journal ID | 40733 |
Article Category | Article |
Authors | Gyawali, Prajwal, Richards, Ross S, Nwose, Ezekiel Uba and Bwititi, Phillip T |
Journal Title | Clinical Lipidology |
Journal Citation | 7 (6), pp. 709-719 |
Number of Pages | 11 |
Year | Dec 2012 |
Publisher | Taylor & Francis |
ISSN | 1746-0875 |
1758-4299 | |
1758-4302 | |
Digital Object Identifier (DOI) | https://doi.org/10.2217/CLP.12.65 |
Web Address (URL) | https://www.tandfonline.com/doi/abs/10.2217/clp.12.65 |
Abstract | Whole-blood viscosity (WBV) depends on vascular geometry and blood physiological constituents. Diabetes mellitus, hypertension, dyslipidemia and obesity – the major components of metabolic syndrome (MetS) – can independently affect blood vessels and microcirculation. MetS is the state of oxidative stress and systemic inflammation. Pro-oxidant and inflammatory cytokines induce endothelial dysfunction. Morphological alterations of erythrocytes could be a consequence of decreased erythrocytes deformability, oxidative stress and systemic inflammation. These events altogether lead to increased WBV. In this review, the effect of WBV in different components of the MetS and WBV with regard to oxidative stress and inflammation – common states in chronic disease – are discussed. |
Keywords | diabetes mellitus; hypertension; metabolic syndrome; obesity whole-blood viscosity |
ANZSRC Field of Research 2020 | 320102. Haematology |
320101. Cardiology (incl. cardiovascular diseases) | |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | Charles Sturt University |
Charles Darwin University |
https://research.usq.edu.au/item/yyq06/whole-blood-viscosity-and-metabolic-syndrome
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