Oxidative stress research: a framework to relate basic science to clinical practice
Article
Nwose, Ezekiel Uba, Bwititi, Phillip Taderera and Chalada, Melissa Judith.. 2013. "Oxidative stress research: a framework to relate basic science to clinical practice." Oxidants and Antioxidants in Medical Science. 2 (4), pp. 225-229.
Article Title | Oxidative stress research: a framework to relate basic science to clinical practice |
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Article Category | Article |
Authors | Nwose, Ezekiel Uba, Bwititi, Phillip Taderera and Chalada, Melissa Judith. |
Journal Title | Oxidants and Antioxidants in Medical Science |
Journal Citation | 2 (4), pp. 225-229 |
Number of Pages | 5 |
Year | 2013 |
Place of Publication | Belgium |
ISSN | 2146-8389 |
Web Address (URL) | https://www.ejmoams.com/abstract/oxidative-stress-research-a-framework-to-relate-basic-science-to-clinical-practice-47460.html |
Abstract | Oxidative stress research has been going on for a long time, but a review of recent free radicals research literature presents little or no framework for translation into clinical practice. Instead, there seems to be a paradigm shift whereby the current trend in oxidative stress research has moved from the yet-to-be translated basic concepts to new hypotheses and theories that can hardly be separated from the basics. This commentary focuses on the issue of ‘translating basic science to clinical practice’; with a view to draw attention to untranslated basic concepts, some new theories that are inseparable from the basic concepts, the gap between negative vs positive research outcomes, and the gap between diagnostic pathology vs research in assessment of oxidative stress. Attempt is made to explain how oxidative stress research can be adopted in clinical practice and pathology, in particular. Importantly, this article identifies that the confounding effects of various default metabolites with anti- or pro-oxidant properties require to be acknowledged; and also hypothesize a framework to relate any new theory to the basics as well as to clinical practice. |
Keywords | Clinical practice |
Contains Sensitive Content | Does not contain sensitive content |
ANZSRC Field of Research 2020 | 420605. Preventative health care |
Byline Affiliations | Charles Darwin University |
Charles Sturt University |
Permalink -
https://research.usq.edu.au/item/z1y76/oxidative-stress-research-a-framework-to-relate-basic-science-to-clinical-practice
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