Influence of anticoagulants on determination of H2O2 levels in blood: Comparison of citrate and EDTA

Article

Nwose, EU, Bwititi, P. and Chalada, MJ. 2018. "Influence of anticoagulants on determination of H2O2 levels in blood: Comparison of citrate and EDTA." International Journal of Pathology and Clinical Research. 4 (2). https://doi.org/10.23937/2469-5807/1510083
Article Title

Influence of anticoagulants on determination of H2O2 levels in blood: Comparison of citrate and EDTA

Article CategoryArticle
AuthorsNwose, EU, Bwititi, P. and Chalada, MJ
Journal TitleInternational Journal of Pathology and Clinical Research
Journal Citation4 (2)
Article Number083
Number of Pages5
Year2018
PublisherClinMed International Library
Place of PublicationUnited States
ISSN2469-5807
Digital Object Identifier (DOI)https://doi.org/10.23937/2469-5807/1510083
Web Address (URL)https://www.clinmedjournals.org/articles/ijpcr/international-journal-of-pathology-and-clinical-research-ijpcr-4-083.php?jid=ijpcr
Abstract

Background
H2O2 is supposed to be part of the laboratory test panel for assessment of oxidative stress. This molecule contributes to oxidative stress by reacting with Fe2+ ions to produce hydroxyl radicals. Anticoagulants, including citrate and EDTA chelate Fe2+, possibly have implications in oxidative stress studies especially when H2O2 is measured.

Objective
This brief commentary is on the measurability of H2O2 in citrated and EDTA blood samples.

Method
Laboratory evaluation was performed using blood samples of 30 sheep collected in EDTA and citrate tubes. Samples were centrifuged, and plasma separated. H2O2 was determined using the Biotech H2O2 560 assay protocol on plasma. The ratio of EDTA to iron was also estimated to help interpret levels of H2O2 in EDTA blood.

Results
There was measurable H2O2 reaction in citrate samples, but not in the EDTA blood. Based on brand sterile hematology tubes containing 1.8 mg EDTA per mL blood; approximately 4:1 ratio of EDTA to iron is estimated. Presuming this calculated ratio is a reflection of the true iron levels in the sheep's blood, the test results support the suggestion that ratio of EDTA to iron is greater than 1:1.

Conclusion
Evidence is hereby presented to advance that EDTA anticoagulant is unsuitable for laboratory testing of H2O2 in plasma. Further studies may be needed to ascertain the effects of different anticoagulants on H2O2 in whole blood and haemolysate to see how these can be compared to plasma. This is relevant to establish a standard protocol for integration of H2O2 test for assessment of full oxidative stress panel in clinical practice.

KeywordsAnticoagulants; Blood samples; Diagnostic lab; Hydrogen peroxide; Oxidative stress
Contains Sensitive ContentDoes not contain sensitive content
ANZSRC Field of Research 2020420605. Preventative health care
Byline AffiliationsCharles Sturt University
Charles Darwin University
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Mandoh, Sulaiman Lansana, Rossiter, Rachel, Bwititi, Phillip and Nwose, Uba. 2020. "Psychosocial impact of the COVID-19 pandemic as perceived by Australian based-West Africans who survived the 2014-2016 Ebola Virus Disease epidemic in West Africa: A Descriptive cross-sectional survey." 7th Western NSW Health Research Network Symposium 2020. 12 - 12 Nov 2020 Australia.
Integration of eye care into primary healthcare tier in Nigeria health system: A case for Delta State
Moyegbone, John E, Nwose, Ezekiel U, Nwajei, Samuel D, Agege, Emmanuel A, Odoko,Joseph O and Igumbor, Eunice O. 2020. "Integration of eye care into primary healthcare tier in Nigeria health system: A case for Delta State." Clinical Medical Reviews and Reports. 3 (2), pp. 1-6. https://doi.org/10.31579/2690-8794/038
Epidemiology of visual impairment: focus on Delta State, Nigeria
Moyegbone, John E., Nwose, Ezekiel U., Nwajei, Samuel D., Odoko, Joseph O., Agege, Emmanuel A. and Igumbor, Eunice O.. 2020. "Epidemiology of visual impairment: focus on Delta State, Nigeria." International Journal of Community Medicine and Public Health. 7 (10), pp. 4171-4179. https://doi.org/10.18203/2394-6040.ijcmph20204392
Opportunities for conducting a non-funded translational clinical research in rural and suburban low-mid income communities: 6-years’ case review
Nwose, EU. 2020. "Opportunities for conducting a non-funded translational clinical research in rural and suburban low-mid income communities: 6-years’ case review." Journal of Health Science and Education. 4 (3), pp. 1-10. https://doi.org/10.0000/JHSE.1000188
Complementary antioxidant medicine in COVID-19 management and the place of haematology evaluation: Brief critical and scoping review-based commentary
Bwititi, PT and Nwose, EU. 2020. "Complementary antioxidant medicine in COVID-19 management and the place of haematology evaluation: Brief critical and scoping review-based commentary." Hematology and Medical Oncology. 5. https://doi.org/10.15761/HMO.1000210
Epidemiology of malaria as it relates to utilization of insecticide treated nets among pregnant women and under five years children in South-South Nigeria
Odoko, Joseph O., Nwose, Ezekiel U., Nwajei, Samuel D., Agege, Emmanuel A., Moyegbone, John E. and Igumbor, Eunice O.. 2020. "Epidemiology of malaria as it relates to utilization of insecticide treated nets among pregnant women and under five years children in South-South Nigeria." International Journal of Community Medicine and Public Health. 7 (10), p. 7. https://doi.org/10.18203/2394-6040.ijcmph20204390
Primary healthcare on utilization of insecticide treated nets among pregnant mothers and carers of children in South–South Nigeria
Odoko, Joseph O, Nwose, Ezekiel U., Nwajei, Samuel D.D., Igumbor, Eunice O, Agege, Emmanuel A. and Moyegbone, John E. 2020. "Primary healthcare on utilization of insecticide treated nets among pregnant mothers and carers of children in South–South Nigeria." Clinical Medical Reviews and Reports. 3 (2). https://doi.org/10.31579/2690-8794/035
My yearly medical expedition to Nigeria, by Australia-based doctor
Okonji, Charles and Nwose, Ezekiel Uba. 2020. "My yearly medical expedition to Nigeria, by Australia-based doctor ." The Nation.
Impact of public health lecture intervention on consumption behaviour towards indigenous staple carbohydrate foods
Onodu, Bonaventure, Culas, Richard and Nwose, Ezekiel U.. 2020. "Impact of public health lecture intervention on consumption behaviour towards indigenous staple carbohydrate foods." International Journal of Community Medicine and Public Health. 7 (3), pp. 841-847. https://doi.org/10.18203/2394-6040.ijcmph20200932
Nutritional and health values of indigenous root and tuber crops compared to imported carbohydrate (such as wheat): A case study example from Delta state Nigeria
Onodu, Bonaventure C., Culas, Richard J. and Nwose, Ezekiel U.. 2020. "Nutritional and health values of indigenous root and tuber crops compared to imported carbohydrate (such as wheat): A case study example from Delta state Nigeria." 64th Annual Conference of the Australian Agricultural and Resource Economics Society (AARES 2020). Perth, Australia 12 202 - 14 Feb 2020 Australia. https://doi.org/10.22004/ag.econ.305252
Health values of cassava compared to wheat and yam in relation to diabetes and dyslipidaemia management
Onodu, Bonaventure, Culas, Richard and Nwose, Ezekiel U.. 2020. "Health values of cassava compared to wheat and yam in relation to diabetes and dyslipidaemia management." International Journal of Community Medicine and Public Health. 7 (2), pp. 791-798. https://doi.org/10.18203/2394-6040.ijcmph20200469
Gestational diabetes management postpartum in primary healthcare facilities: Mini review update on Delta State Nigeria
Orove, Annette A, Garba, Ahmed, Orru, Mary O, Otovwe, Agofure, Igumbor, Eunice O and Nwose, Ezekiel U. 2020. "Gestational diabetes management postpartum in primary healthcare facilities: Mini review update on Delta State Nigeria." Clinical Medical Reviews and Reports. 2 (7). https://doi.org/10.31579/2690-8794/040
A vaccine for coronavirus is the goal, but what does it take to get there?
Taylor, Tegan and Nwose, Ezekiel Uba. 2020. "A vaccine for coronavirus is the goal, but what does it take to get there? " ABC News.
Charles Sturt University lecturer Dr Ezekiel (Uba) Nwose said it's not only humans who are at risk of COVID-19
Vass, Erika and Nwose, Ezekiel (Uba). 2020. "Charles Sturt University lecturer Dr Ezekiel (Uba) Nwose said it's not only humans who are at risk of COVID-19 ." Central Western Daily.
Cultural practice being recycled in modern families: The education and health nexus
Nwose, Ezekiel Uba. 2019. "Cultural practice being recycled in modern families: The education and health nexus." African-Australia Education and Health Narratives Colloquium 2019. Northern Territory, Australia 24 - 25 Oct 2019 Australia.
Evaluation of gender differences in exercise adherence for low back pain: case reviews and survey
Noon, Chelsea T., Nwose, Ezekiel U. and Breheny, Louise. 2019. "Evaluation of gender differences in exercise adherence for low back pain: case reviews and survey." European Journal of Physiotherapy. 21 (1), pp. 49-55. https://doi.org/10.1080/21679169.2018.1468815
Impact of gas flaring in Ubeji metropolis of Delta State Nigeria: a comparative survey of environment health effects
Akuirene, Omatseye Alero, Adjene, Josiah O., Obi, Nkemdilim I. and Nwose, Ezekiel Uba. 2019. "Impact of gas flaring in Ubeji metropolis of Delta State Nigeria: a comparative survey of environment health effects." International Journal of Scientific Reports. 5 (10), pp. 283-290. https://doi.org/10.18203/issn.2454-2156.IntJSciRep20194249
Diabetes mellitus literacy in a regional community of a developed country
Chen, Adelene, Chidarikire, Thelma, Sarswat, Drishti, Parissi, Cesidio and Nwose, Ezekiel Uba. 2019. "Diabetes mellitus literacy in a regional community of a developed country." Acta Biomedica de l'Ateneo Parmense. 90 (4), pp. 482-488. https://doi.org/10.23750/abm.v90i4.7687
Diabetes registry and service in Nigerian suburban-based tertiary healthcare facility
Gbeinbo, Fortunatus D., Igumbor, Eunice O., Agofure, Otovwe, Obodo, Chinedu O., Olu-Ero, Emmanuel and Nwose, Ezekiel U.. 2019. "Diabetes registry and service in Nigerian suburban-based tertiary healthcare facility." International Journal of Community Medicine and Public Health. 7 (1), p. 6. https://doi.org/10.18203/2394-6040.ijcmph20195862
Diabetes registry initiative in Delta State Nigeria: narrative of the kick-off experience
Igumbor, Eunice O., Agofure, Otovwe, Onyimi, Chukwuma, Bwititi, Phillip T. and Nwose, Ezekiel U.. 2019. "Diabetes registry initiative in Delta State Nigeria: narrative of the kick-off experience." International Journal of Community Medicine and Public Health. 7 (1), p. 6. https://doi.org/10.18203/2394-6040.ijcmph20195831
Development of diabetes register in low-mid income country: survey of healthcare professionals’ behavioural change wheel
Igumbor, E.O., Agofure, O., Oshionwu, E., Bwititi, Phillip T. and Nwose, Ezekiel U.. 2019. "Development of diabetes register in low-mid income country: survey of healthcare professionals’ behavioural change wheel." International Journal of Community Medicine and Public Health. 7 (1), pp. 1-8. https://doi.org/10.18203/2394-6040.ijcmph20195824
Promoting African indigenous vegetables and its medical nutrition properties: A mini-narrative review based on Ukwani communities of Delta State Nigeria
Ishiekwene, IC, Dada, TE, Odoko, JO and Nwose, EU. 2019. "Promoting African indigenous vegetables and its medical nutrition properties: A mini-narrative review based on Ukwani communities of Delta State Nigeria." Integrative Food, Nutrition and Metabolism. 6, pp. 1-6. https://doi.org/10.15761/IFNM.1000256
Prospects of diabetes registry and standard care at primary health facilities in Nigeria: experiential note
Ndubueze, Pleasant C., Igumbor, Eunice O., Agofure, Otovwe, Okwelum, Anthonia C., Ozuem, Prince C. and Nwose, Ezekiel U.. 2019. "Prospects of diabetes registry and standard care at primary health facilities in Nigeria: experiential note." International Journal of Community Medicine and Public Health. 7 (1), pp. 144-147. https://doi.org/10.18203/2394-6040.ijcmph20195844
Writing a project proposal: addendum to development of diabetes register series
Nwose, Ezekiel U.. 2019. "Writing a project proposal: addendum to development of diabetes register series." International Journal of Community Medicine and Public Health. 7 (1), pp. 377-380. https://doi.org/10.18203/2394-6040.ijcmph20195884
Training Handbook for Intensive Diabetes Peer-Education
Nwose, Ezekiel 'Uba' and Agofure, Otovwe. 2019. Training Handbook for Intensive Diabetes Peer-Education. Mauritius. LAP LAMBERT Academic Publishing.
Evaluation of ADL and BMI in the management of diabetes mellitus at secondary and tertiary health facilities
Nwose, Ezekiel U., Ekotogbo, Benjamin, Ogbolu, Christabel N., Mogbusiaghan, Meyiwa, Agofure, Otovwe and Igumbor, Eunice O.. 2019. "Evaluation of ADL and BMI in the management of diabetes mellitus at secondary and tertiary health facilities." Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 13 (3), pp. 2266-2271. https://doi.org/10.1016/j.dsx.2019.05.033
Development of diabetes register in low-mid income country VII: summary of series
Nwose, Ezekiel U., Igumbor, Eunice O., Agofure, Otovwe, Bwititi, Phillip T., Oshionwu, Echinei J., Odufu, Alex and Okuzor, John N.. 2019. "Development of diabetes register in low-mid income country VII: summary of series." International Journal of Community Medicine and Public Health. 7 (1), p. 5. https://doi.org/10.18203/2394-6040.ijcmph20195872
Barriers in determining prevalence of type 2 diabetes mellitus among postpartum GDM: The research and retraining needs of healthcare professionals
Nwose, E.U., Mogbusiaghan, M., Bwititi, P.T., Adoh, G., Agofure, O. and Igumbor, E.O.. 2019. "Barriers in determining prevalence of type 2 diabetes mellitus among postpartum GDM: The research and retraining needs of healthcare professionals." Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 13 (2019), pp. 2533-2539. https://doi.org/10.1016/j.dsx.2019.07.002
Prevalence and correlations of hepatorenal functions in diabetes and cardiovascular disease among stratified adults
Nwose, Ezekiel Uba, Obianke, Joshua, Richards, Ross Stuart, Bwititi, Phillip Tederera and Igumbor, Eunice Obiajuru. 2019. "Prevalence and correlations of hepatorenal functions in diabetes and cardiovascular disease among stratified adults." Acta Biomedica de l'Ateneo Parmense. 90 (1), pp. 97-103. https://doi.org/10.23750/abm.v90i1.6576
The odds that working women will accept cervical cancer screening and HPV vaccination
Nwose, Ezekiel Uba, Okwe, Uchechukwuka Nnemdi and Chime, Helen. 2019. "The odds that working women will accept cervical cancer screening and HPV vaccination." International Journal of Research in Medical Sciences. 7 (5). https://doi.org/10.18203/2320-6012.ijrms20191676
Diabetes peer-education on food choices part I: Development of framework
Nwose, EU, Onokade, M, Agofure, O and Igumbor, EO. 2019. "Diabetes peer-education on food choices part I: Development of framework." Integrative Food, Nutrition and Metabolism. 6. https://doi.org/10.15761/IFNM.1000240
Diabetes peer-education on food choices part II: Adoptability of menu plans in low-mid income communities
Nwose, UE, Onokade, M, Agofure, O, Johnson, E and Igumbor, EO. 2019. "Diabetes peer-education on food choices part II: Adoptability of menu plans in low-mid income communities." Integrative Food, Nutrition and Metabolism. 6, pp. 1-4. https://doi.org/10.15761/IFNM.1000248
Diabetes registry and service in Nigerian suburban areas: experience at a secondary healthcare facility
Obodo, Chinedu O., Igumbor, Eunice O., Agofure, Otovwe, Gbeinbo, Fortunatus D., Ocheli, Henzy and Nwose, Ezekiel U.. 2019. "Diabetes registry and service in Nigerian suburban areas: experience at a secondary healthcare facility." International Journal of Community Medicine and Public Health. 7 (1), p. 7. https://doi.org/10.18203/2394-6040.ijcmph20195852
Factors influencing the acceptance of cervical cancer screening among civil servants in Delta State Secretariat
Okwe, Uchechukwuka Nnemdi, Chime, Helen and Nwose, Ezekiel Uba. 2019. "Factors influencing the acceptance of cervical cancer screening among civil servants in Delta State Secretariat." International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 8 (4), pp. 1380-1386. https://doi.org/10.18203/2320-1770.ijrcog20191185
Demographics and knowledge of cervical cancer of female civil servants in Delta State on Nigeria
Okwe, Uchechukwuka Nnemdi, Chime, Helen and Nwose, Ezekiel Uba. 2019. "Demographics and knowledge of cervical cancer of female civil servants in Delta State on Nigeria." International Journal of Community Medicine and Public Health. 6 (4), pp. 1374-1379. https://doi.org/10.18203/2394-6040.ijcmph20191362
Factors influencing the acceptance of HPV vaccine among civil servants in Delta State Secretariat
Okwe, Uchechukwuka Nnemdi, Chime, Helen and Nwose, Ezekiel Uba. 2019. "Factors influencing the acceptance of HPV vaccine among civil servants in Delta State Secretariat." International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 8 (4), pp. 1227-1232. https://doi.org/10.18203/2320-1770.ijrcog20191176
Prospects of diabetes registry in suburban community of Nigeria: experience at a private general practice
Okwelum, Anthonia C., Igumbor, Eunice O., Agofure, Otovwe, Ndubueze, Pleasant C., Aninze, Kenneth and Nwose, Ezekiel U.. 2019. "Prospects of diabetes registry in suburban community of Nigeria: experience at a private general practice." International Journal of Community Medicine and Public Health. 7 (1), p. 5. https://doi.org/10.18203/2394-6040.ijcmph20195836
Altruism: Brief review of current opinions and implications on community emergency medicine
Oshionwu, EJ and Nwose, EU. 2019. "Altruism: Brief review of current opinions and implications on community emergency medicine." International Journal of Critical Care and Emergency Medicine. 5 (1), p. 066. https://doi.org/10.23937/2474-3674/1510066
Parental perception of girl-child early marriage amongst the Urhobos in Nigeria
Agege, E.A., Nwose, Ezekiel U. and Odjimogho, Stella. 2018. "Parental perception of girl-child early marriage amongst the Urhobos in Nigeria." International Journal of Community Medicine and Public Health. 5 (8), pp. 3185-3190. https://doi.org/10.18203/2394-6040.ijcmph20183049
Parents’ perception on factors of early marriage among the Urhobos in Delta State of Nigeria
Agege, Emmanuel A., Nwose, Ezekiel Uba and Odjimogho, Stella. 2018. "Parents’ perception on factors of early marriage among the Urhobos in Delta State of Nigeria." International Journal of Community Medicine and Public Health. 5 (2), pp. 411 - 415. https://doi.org/10.18203/2394-6040.ijcmph20180213
Blood glucose and pressure controls in diabetic kidney disease: narrative review of adherence, barriers and evidence of achievement
Gardiner, Fergus William, Nwose, Ezekiel Uba, Bwititi, Phillip Taderera, Crockett, Judith and Wang, Lexin. 2018. "Blood glucose and pressure controls in diabetic kidney disease: narrative review of adherence, barriers and evidence of achievement." Journal of Diabetes and Its Complications. 32 (1), pp. 104-112. https://doi.org/10.1016/j.jdiacomp.2017.09.008
Adherence to blood pressure and glucose recommendations in chronic kidney disease hospital inpatients: Clinical inertia and patient adherence
Gardiner, Fergus William, Nwose, Ezekiel Uba, Bwititi, Phillip Taderera, Crockett, Judith and Wang, Lexin. 2018. "Adherence to blood pressure and glucose recommendations in chronic kidney disease hospital inpatients: Clinical inertia and patient adherence." Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 12 (3), pp. 291-300. https://doi.org/10.1016/j.dsx.2017.12.007
Does a hospital diabetes inpatient service reduce blood glucose and HbA1c levels? A prospective cohort study
Gardiner, Fergus William, Nwose, Ezekiel Uba, Bwititi, Phillip Taderera, Crockett, Judith and Wang, Lexin. 2018. "Does a hospital diabetes inpatient service reduce blood glucose and HbA1c levels? A prospective cohort study." Annals of Medicine and Surgery. 26, pp. 15-18. https://doi.org/10.1016/j.amsu.2017.12.010
Prevention of mother-to-child transmission of HIV in Delta State of Nigeria: Evaluation of the early infant diagnosis program
Ibobo, J.A., Chime, H. and Nwose, E.U.. 2018. "Prevention of mother-to-child transmission of HIV in Delta State of Nigeria: Evaluation of the early infant diagnosis program." Journal of Health Science Research. 3 (1), pp. 16-23. https://doi.org/10.18311/jhsr/0/20020
Perceptions and unmet expectations of undergraduate students on the role of counselling in academic achievement: Implication for academic development program review
Iyeke, Patrick Okoh, Oneyma, Lucky Chukwunalu and Nwose, Ezekiel Uba. 2018. "Perceptions and unmet expectations of undergraduate students on the role of counselling in academic achievement: Implication for academic development program review." World Journal of Education. 8 (5), pp. 88-96. https://doi.org/10.5430/wje.v8n5p88
Research statistical method seemingly non-transferrable to clinical pathology practice: A case for d-dimer quantitative testing
Nwose, Ezekiel Uba, Bwititi, Phillip Taderera and Richards, Ross Stuart. 2018. "Research statistical method seemingly non-transferrable to clinical pathology practice: A case for d-dimer quantitative testing." International Journal of Pathology and Clinical Research. 4 (2). https://doi.org/10.23937/2469-5807/1510084
Evaluation of inter-current illness intervening lifestyle in stratified age groups: focus on diabetes and its cardiovascular complication
Nwose, Ezekiel U., Ojugbeli, Christian, Bwititi, Phillip T. and Igumbor, Eunice O.. 2018. "Evaluation of inter-current illness intervening lifestyle in stratified age groups: focus on diabetes and its cardiovascular complication." International Journal of Health and Rehabilitation Sciences. 7 (3), pp. 116-130. https://doi.org/10.5455/ijhrs.0000000150
Evaluation of utilization of insecticide treated nets among pregnant women in Bayelsa State of Nigeria: a case study of Sagbama community
Odoko, Joseph O., Nwose, Ezekiel U. and Igumbor, Eunice O.. 2018. "Evaluation of utilization of insecticide treated nets among pregnant women in Bayelsa State of Nigeria: a case study of Sagbama community." International Journal of Research in Medical Sciences. 6 (8), pp. 2571-2577. https://doi.org/10.18203/2320-6012.ijrms20183234
Diet and lifestyle habits: Association with cardiovascular disease indices in a Nigerian sub-population
Oguoma, Victor M., Nwose, Ezekiel U., Skinner, Timothy C., Richards, Ross S. and Bwititi, Phillip T.. 2018. "Diet and lifestyle habits: Association with cardiovascular disease indices in a Nigerian sub-population." Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 12 (5), pp. 653-659. https://doi.org/10.1016/j.dsx.2018.04.007
Facts about dietary fibre in cassava: Implication for diabetes’ medical nutrition therapy
Onodu, Bonaventure C, Culas, Richard J and Nwose, Ezekiel U. 2018. "Facts about dietary fibre in cassava: Implication for diabetes’ medical nutrition therapy." Integrative Food, Nutrition and Metabolism. 5 (3). https://doi.org/10.15761/ifnm.1000216
Revitalizing the Agricultural Sector in Nigeria: Implications for Root and Tuber Crops Value Chains and Contribution to Health Care
Onodu, Bonaventure C., Culas, Richard J. and Nwose, Ezekiel U.. 2018. "Revitalizing the Agricultural Sector in Nigeria: Implications for Root and Tuber Crops Value Chains and Contribution to Health Care." Waechter, Sarah (ed.) Agricultural Production: Management, Opportunities and Challenges. United States. Nova Science Publishers. pp. 1-19
World diabetes day 2017 focus: antepartum hyperglycaemia (or gestational prediabetes) is more in women below 40 years
Orru, M. I., Nwose, E. U., Bwititi, P. T. and Igumbor, E. O.. 2018. "World diabetes day 2017 focus: antepartum hyperglycaemia (or gestational prediabetes) is more in women below 40 years." International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 7 (1), pp. 355-356. https://doi.org/10.18203/2320-1770.ijrcog20175491
Screening for gestational diabetes: evaluation of prevalence in age-stratified subgroups at Central hospital Warri Nigeria
Orru, M. I., Nwose, E. U., Bwititi, P. and Igumbor, E. O.. 2018. "Screening for gestational diabetes: evaluation of prevalence in age-stratified subgroups at Central hospital Warri Nigeria." International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 7 (1), pp. 63-68. https://doi.org/10.18203/2320-1770.ijrcog20175487
Diabetes care in delta state of Nigeria: An expository review
Agofure, O, Oyewole, OE, Igumbor, EO and Nwose, EU. 2018. "Diabetes care in delta state of Nigeria: An expository review." Diabetes Updates. 1 (1), pp. 1-8. https://doi.org/10.15761/DU.1000106
Evaluation of acetylator phenotype of isoniazid among tuberculosis patients in delta state Nigeria: update on management of toxicity
Nwose, Ezekiel U., Aganbi, Eferhire and Onyia, Innocent C.. 2017. "Evaluation of acetylator phenotype of isoniazid among tuberculosis patients in delta state Nigeria: update on management of toxicity." International Journal of Research in Medical Sciences. 4 (6), pp. 2348-2354. https://doi.org/10.18203/2320-6012.ijrms20161813
Impact of HIV/AIDS awareness on the sexual behaviour of undergraduate students
Ahmed, A., Nwose, E. U. and Nwajei, S. D.. 2017. "Impact of HIV/AIDS awareness on the sexual behaviour of undergraduate students." Journal of Health Science Research. 2 (2), pp. 5-9.
Liver biomarkers in diabetes mellitus, prediabetes and periodontal disease: evidence of triangular correlation
Aganbi, Eferhire, Effiong, Donald, Anyasodor, Anayochukwu Edward, Oluero, Emmanuel, Tietie, Mudiaga Luke and Nwose, Ezekiel Uba. 2017. "Liver biomarkers in diabetes mellitus, prediabetes and periodontal disease: evidence of triangular correlation." World Journal of Medical Sciences. 14 (2), pp. 39-46.
Legalities of child marriage in Nigeria: Implications on health and strategies of prevention
Agege, EA, Nwose, EU, Odjimogho, S and Igumbor, EO. 2017. "Legalities of child marriage in Nigeria: Implications on health and strategies of prevention." Sexual Health Issues. 1 (1), pp. 1-4. https://doi.org/10.15761/SHI.1000105
Prevalence of hyperglycemia and risk factors for orodental disease in Nigeria: Implications of opportunistic screening
Anyasodor, Anayochukwu Edward, Nwose, Ezekiel Uba, Bwititi, Phillip Taderera, Aganbi, Eferhire, Richards, Ross, Mudiaga, Luke Itietie, Oguoma, Victor Maduabuchi and Enemchukwu, Salome Chijioke. 2017. "Prevalence of hyperglycemia and risk factors for orodental disease in Nigeria: Implications of opportunistic screening." Indian Journal of Dental Research. 28 (5), pp. 507-513. https://doi.org/10.4103/ijdr.IJDR_304_17
Triangular relationship of blood sugar, obesity and periodontal disease at individual vs. population level
Anyasodor, Anayochukwu Edward A, Nwose, Ezekiel Uba, Bwititi, Phillip Taderera, Richards, Ross Stuart, Okolie, Kenneth and Mudiaga, Luke Itietie. 2017. "Triangular relationship of blood sugar, obesity and periodontal disease at individual vs. population level." World Journal of Medical Sciences. 14 (3), pp. 52-56.
Co-morbidity of diabetes mellitus and orodental diseases in Nigeria
Anyasodor, nayochukwu Edward, Nwose, Ezekiel Uba, Richards, R., Bwititi, P., Digban, Kester Awharentomah, Mudiaga, Luke Itietie, Aganbi, Eferhire A and Ojodeme, Okuguni. 2017. "Co-morbidity of diabetes mellitus and orodental diseases in Nigeria." Current Diabetes Reviews. 13 (3), pp. 289-299. https://doi.org/10.2174/1573399812666160413114146
Prediabetes and cardiovascular complications screening in Nigeria: A family case presentation
Anyasodor, Anayochukwu Edward, Nwose, Ezekiel Uba, Richards, Ross Stuart, Bwititi, Phillip Taderera, Mudiaga, Luke Itietie and Aganbi, Eferhire. 2017. "Prediabetes and cardiovascular complications screening in Nigeria: A family case presentation." Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 11 (4), pp. 273-275. https://doi.org/10.1016/j.dsx.2016.12.006
Quantitative eradicative cure profile of HIV/AIDS using electromagnetic (EM) wave destruction technique
Enaibe, Edison A., Erhieyovwe, Erhieyovwe, Nwose, Ezekiel U. and Umukoro, Judith. 2017. "Quantitative eradicative cure profile of HIV/AIDS using electromagnetic (EM) wave destruction technique." Journal of Scientific Research and Reports. 13 (3), pp. 1-28. https://doi.org/10.9734/JSRR/2017/30870
The control and possible eradication of HIV/AIDS using electromagnetic (EM) radiation
Enaibe, Edison A., Erhieyovwe, Akpata, Umukoro, Judith and Nwose, Ezekiel U.. 2017. "The control and possible eradication of HIV/AIDS using electromagnetic (EM) radiation." Journal of Scientific Research and Reports. 15 (2), pp. 1-31. https://doi.org/10.9734/JSRR/2017/34834
Services aimed at achieving desirable clinical outcomes in patients with chronic kidney disease and diabetes mellitus: A narrative review
Gardiner, Fergus William, Nwose, Ezekiel Uba, Bwititi, Phillip Taderera, Crockett, Judith and Wang, Lexin. 2017. "Services aimed at achieving desirable clinical outcomes in patients with chronic kidney disease and diabetes mellitus: A narrative review." Sage Open Medicine. 5. https://doi.org/0.1177/2050312117740989
Outpatient cardiac rehabilitation: Effects on patient improvement outcomes
Gardiner, F., Regan, Elizabeth, Nwose, Ezekiel U., Bwititi, Phillip T., Crockett, Judith and Wang, Lexin. 2017. "Outpatient cardiac rehabilitation: Effects on patient improvement outcomes." Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 11 (Supplement 2), pp. S1025-S1030. https://doi.org/10.1016/j.dsx.2017.07.034
Reducing the mother-to-child transmission of HIV: findings from an early infant diagnosis program in Delta state Nigeria
Ibobo, Judith A., Nwose, Ezekiel Uba and Chime, Hellen. 2017. "Reducing the mother-to-child transmission of HIV: findings from an early infant diagnosis program in Delta state Nigeria." International Journal of Community Medicine and Public Health. 4 (12), pp. 4352-4357. https://doi.org/10.18203/2394-6040.ijcmph20175085
Implication of oestrogen in the development of breast cancer: a brief narrative review
Nweze, Princess, Nwose, Ezekiel U. and Igumbor, Eunice O.. 2017. "Implication of oestrogen in the development of breast cancer: a brief narrative review." International Journal of Research in Medical Sciences. 5 (12), pp. 5088-5092. https://doi.org/10.18203/2320-6012.ijrms20175076
Metabolic Syndromes and Public Health Policies in Africa
Nwose, E.U., Bwititi, P.T. and Oguoma, V.M.. 2017. "Metabolic Syndromes and Public Health Policies in Africa." Kuete, Victor (ed.) Medicinal Spices and Vegetables from Africa: Therapeutic Potential Against Metabolic, Inflammatory, Infectious and Systemic Diseases. United Kingdom. Academic Press. pp. 109-131
Development of public health program for type 1 diabetes in a university community: preliminary evaluation of behavioural change wheel
Nwose, E.U., Digban, K.A., Anyasodor, A.E., Bwititi, P.T., Richards, R.S. and Igumbor, E.O.. 2017. "Development of public health program for type 1 diabetes in a university community: preliminary evaluation of behavioural change wheel." Acta Biomedica de l'Ateneo Parmense. 88 (3), pp. 281-288.
Ethnopharmacological values of cassava and its potential for diabetes and dyslipidemia management: Knowledge survey and critical review of report
Nwose, Ezekiel Uba, Onodu, Bonaventure C., Anyasodor, Anayochukwu Edward, Sedowo, Mathew O., Okuzor, John N. and Culas, Richard J.. 2017. "Ethnopharmacological values of cassava and its potential for diabetes and dyslipidemia management: Knowledge survey and critical review of report." Journal of Intercultural Ethnopharmacology. 6 (3), pp. 260-266. https://doi.org/10.5455/jice.20170606094119
Utilization of insecticide treated nets against malaria among pregnant women in Southern Nigeria
Odoko, J. O., Nwose, E. U. and Igumbor, E. O.. 2017. "Utilization of insecticide treated nets against malaria among pregnant women in Southern Nigeria." International Journal of Research in Medical Sciences. 5 (11), pp. 4661-4666. https://doi.org/10.18203/2320-6012.ijrms20174913
Cardiovascular disease risk factors in a Nigerian population with impaired fasting blood glucose level and diabetes mellitus
Oguoma, Victor M., Nwose, Ezekiel U., Ulasi, Ifeoma I., Akintunde, Adeseye A., Chukwukelu, Ekene E., Bwititi, Phillip T., Richards, R. and Skinner, Timothy C.. 2017. "Cardiovascular disease risk factors in a Nigerian population with impaired fasting blood glucose level and diabetes mellitus." BMC Public Health. 17 (1). https://doi.org/10.1186/s12889-016-3910-3
Sexual behaviour, knowledge and use of contraceptives among undergraduate students
Okpokumoku, S.E., Nwajei, S. D and Nwose, E. U. 2017. "Sexual behaviour, knowledge and use of contraceptives among undergraduate students." Journal of Health Science Research. 2 (2), pp. 10-17. https://doi.org/10.18311/jhsr/2017/18113
Health values of cassava compared to wheat and yam: A critical review of carbohydrate/fibre and fat/fibre ratios
Onodu, B.C., Culas, Richard J. and Nwose, Ezekiel. U.. 2017. "Health values of cassava compared to wheat and yam: A critical review of carbohydrate/fibre and fat/fibre ratios." Logotheti, Anastasia, Babu, G.A. and Seo, Deokseok (ed.) 6th International Conference on Research in Chemical, Agricultural and Biological Sciences (RCABS-2017) . Singapore 27 - 28 Mar 2017 Singapore.
Issues of management and monitoring by laboratory methods in respiratory medicine: editorial introduction
Nwose, Ezekiel Uba. 2016. "Issues of management and monitoring by laboratory methods in respiratory medicine: editorial introduction." International Journal of Research in Medical Sciences. 4 (6), pp. 1783-1784. https://doi.org/10.18203/2320-6012.ijrms20161724
Comparison of immunohistochemistry with in situ hybridization methods: discrepancy resolution and implications for low-mid income countries
Nwose, Ezekiel Uba. 2016. "Comparison of immunohistochemistry with in situ hybridization methods: discrepancy resolution and implications for low-mid income countries." Journal of Histotechnology. 39 (1), pp. 21-25. https://doi.org/10.1080/01478885.2015.1115587
Bio-psycho-sociocultural basis of diabetes rehabilitation: case report with implications for cultural competence and physiotherapy
Nwose, Ezekiel Uba and Bwititi, Phillip Taderera. 2016. "Bio-psycho-sociocultural basis of diabetes rehabilitation: case report with implications for cultural competence and physiotherapy." International Journal of Health and Rehabilitation Sciences. 5 (4), pp. 172-182. https://doi.org/10.5455/ijhrs.0000000115
Clinical laboratory testing for smoking toxicity: implications for early identification of respiratory diseases
Nwose, Ezekiel U., Bwititi, Phillip T. and Richards, Ross S.. 2016. "Clinical laboratory testing for smoking toxicity: implications for early identification of respiratory diseases." International Journal of Research in Medical Sciences. 4 (6), pp. 2436-2443. https://doi.org/10.18203/2320-6012.ijrms20161827
Evaluation of oxidative stress and whole blood viscosity for clinical laboratory testing of smoking toxicity
Nwose, Ezekiel U., Bwititi, Phillip T. and Richards, Ross S.. 2016. "Evaluation of oxidative stress and whole blood viscosity for clinical laboratory testing of smoking toxicity." International Journal of Research in Medical Sciences. 4 (6), pp. 2332-2336. https://doi.org/10.18203/2320-6012.ijrms20161810
Drug-disease interactions: narrative review of aspirin in gastric ulcer
Nwose, Ezekiel Uba and Yee, Kwang Choon. 2016. "Drug-disease interactions: narrative review of aspirin in gastric ulcer." Expert Opinion on Drug Metabolism and Toxicology. 12 (9), pp. 1081-1087. https://doi.org/10.1080/17425255.2016.1201064
Association between metabolic syndrome and 10-year risk of developing cardiovascular disease in a Nigerian population
Oguoma, Victor M., Nwose, Ezekiel U., Skinner, Timothy C., Richards, Ross S., Digban, Kester A and Onyia, Innocent C.. 2016. "Association between metabolic syndrome and 10-year risk of developing cardiovascular disease in a Nigerian population." International Health. 8 (5), pp. 354-359. https://doi.org/10.1093/inthealth/ihw013
Association of physical activity with metabolic syndrome in a predominantly rural Nigerian population
Oguoma, Victor M., Nwose, Ezekiel U., Skinner, Timothy C., Richards, Ross S., Digban, Kester A. and Onyia, Innocent C.. 2016. "Association of physical activity with metabolic syndrome in a predominantly rural Nigerian population." Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 10 (1), pp. 13-18. https://doi.org/10.1016/j.dsx.2015.08.010
Anthropometric indices: How they compare in screening of cardio- metabolic risks in a Nigerian sub-population
Oguoma, VM, Nwose, EU, Skinner, TC, Richards, RS, Digban, KA, Onyia, IC and Anyasodor, AE. 2016. "Anthropometric indices: How they compare in screening of cardio- metabolic risks in a Nigerian sub-population." African Journal of Medicine and Medical Sciences. 45 (1), pp. 91-98.
Maximum accuracy obesity indices for screening metabolic syndrome in Nigeria: A consolidated analysis of four cross-sectional studies
Oguoma, Victor M., Nwose, Ezekiel U., Ulasi, Ulasi, Akintunde, Adeseye A., Chukwukelu, Ekene E., Araoye, Matthew A., Edo, Andrew E., Ijoma, Chinwuba K., Onyia, Innocent C., Ogbu, Innocent I., Onyeanusi, Joel C., Digban, Kester A., Onodugo, Obinna D., Adediran, Olufemi, Opadijo, Oladimeji G., Bwititi, Phillip T., Richards, Ross S. and Skinner, Timothy C.. 2016. "Maximum accuracy obesity indices for screening metabolic syndrome in Nigeria: A consolidated analysis of four cross-sectional studies." Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 10 (3), pp. 121-127. https://doi.org/10.1016/j.dsx.2016.01.001
Morning sickness in pregnancy: mini review of possible causes with proposal for monitoring by diagnostic methods
Wylde, Sophie, Nwose, Ezekiel and Bwititi, Phillip. 2016. "Morning sickness in pregnancy: mini review of possible causes with proposal for monitoring by diagnostic methods." International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 5 (2), pp. 261-267. https://doi.org/10.18203/2320-1770.ijrcog20160356
Whole blood viscosity and antiplatelet therapy
Nwose, E. U.. 2015. "Whole blood viscosity and antiplatelet therapy." Western NSW Health Research Network (WHRN) Scientific Symposium 2015. Orange, Australia 01 - 01 Jan 2015 Australia.
Association of abnormal erythrocyte morphology with oxidative stress and inflammation in metabolic syndrome
Gyawali, Prajwal, Richards, Ross S., Bwititi, Phillip T. and Nwose, Ezekiel Uba. 2015. "Association of abnormal erythrocyte morphology with oxidative stress and inflammation in metabolic syndrome." Blood Cells, Molecules and Diseases. 54 (4), pp. 360-363. https://doi.org/10.1016/j.bcmd.2015.01.005
Cardiovascular Risk Assessment in Pre-Diabetes: A Hypothesis A2 - Watson, Ronald Ross
Nwose, Ezekiel Uba. 2015. "Cardiovascular Risk Assessment in Pre-Diabetes: A Hypothesis A2 - Watson, Ronald Ross." Watson, Ronald Ross and Dokken, Betsy B. (ed.) Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular Disease. United States. Academic Press. pp. 103-117
Metabolic signatures of oxidative stress in the red blood cells: Editorial commentary
Nwose, Ezekiel Uba. 2015. "Metabolic signatures of oxidative stress in the red blood cells: Editorial commentary." North American Journal of Medical Sciences. 7 (12), pp. 567-568. https://doi.org/10.4103/1947-2714.172847
Laboratory Testing of Whole Blood Viscosity: The issues of sensitivity and specificity
Nwose, Ezekiel Uba. 2015. Laboratory Testing of Whole Blood Viscosity: The issues of sensitivity and specificity. Germany. LAP LAMBERT Academic Publishing.
Misleading presentation of euglycaemic diabetic ketoacidosis: implication for low-mid income communities
Nwose, Ezekiel Uba and Bwititi, Phillip Taderera. 2015. "Misleading presentation of euglycaemic diabetic ketoacidosis: implication for low-mid income communities." North American Journal of Medical Sciences. 7 (11), pp. 537-539.
Distance training of medical laboratory professionals in Sub-Saharan Africa: Concern over assessment method
Nwose, Ezekiel U and Bwititi, Phillip T.. 2015. "Distance training of medical laboratory professionals in Sub-Saharan Africa: Concern over assessment method." Education for Health: change in learning and practice. 28 (2), pp. 156-157. https://doi.org/10.4103/1357-6283.170127
Increased vulnerability of older adults to DM and its CVD complications: proposal for assessment, management and monitoring by diagnostic methods
Nwose, Ezekiel Uba, Bwititi, Phillip Taderera and Richards, Ross Stuart. 2015. "Increased vulnerability of older adults to DM and its CVD complications: proposal for assessment, management and monitoring by diagnostic methods." International Journal of Research in Medical Sciences. 3 (3), pp. 810-816. https://doi.org/10.5455/2320-6012.ijrms20150359
Metabolic syndrome and prediabetes in Ndokwa community of Nigeria: preliminary study
Nwose, E. U., Oguoma, V. M., Bwititi, P. T. and Richards, R. S.. 2015. "Metabolic syndrome and prediabetes in Ndokwa community of Nigeria: preliminary study." North American Journal of Medical Sciences. 7 (2), pp. 53-58.
Prevalence of cardio-metabolic syndrome in Nigeria: a systematic review
Oguoma, V.M., Nwose, E.U. and Richards, R.S.. 2015. "Prevalence of cardio-metabolic syndrome in Nigeria: a systematic review." Public Health. 129 (5), pp. 413-423. https://doi.org/10.1016/j.puhe.2015.01.017
Prevalence of cardiovascular disease risk factors among a Nigerian adult population: relationship with income level and accessibility to CVD risks screening
Oguoma, Victor Maduabuchi, Nwose, Ezekiel Uba, Skinner, Timothy Chas, Digban, Kester, Onyia, Innocent Chukwu and Richards, Ross Stuart. 2015. "Prevalence of cardiovascular disease risk factors among a Nigerian adult population: relationship with income level and accessibility to CVD risks screening." BMC Public Health. 15 (1). https://doi.org/10.1186/s12889-015-1709-2
Implementation of POCT in the diabetic clinic in a large hospital
Tanyanyiwa, D, Dandara, C, Bhana, SA, Pauly, B, Marule, F, Ramokoka, M, Bwititi, P, Nwose, U and Nkosi, B. 2015. "Implementation of POCT in the diabetic clinic in a large hospital." African Health Sciences. 15 (3), pp. 902-907. https://doi.org/10.4314/ahs.v15i3.26
The association of dyslipidemia with erythrocyte aggregation
Gyawali, Prajwal, Richards, Ross S, Bwititi, Phillip T. and Nwose, Ezekiel Uba. 2015. "The association of dyslipidemia with erythrocyte aggregation ." Clinical Lipidology. 10 (2), pp. 129-135. https://doi.org/10.2217/CLP.15.3
Hemorheology, ankle brachial pressure index (ABPI) and toe brachial pressure index (TBPI) in metabolic syndrome
Gyawali, Prajwal, Richards, Ross S., Tinley, Paul and Nwose, Ezekiel Uba. 2014. "Hemorheology, ankle brachial pressure index (ABPI) and toe brachial pressure index (TBPI) in metabolic syndrome ." Microvascular Research. 95, pp. 31-36. https://doi.org/10.1016/j.mvr.2014.06.013
Screening of cardiovascular disease risk in diabetes: Questions concerning prediabetes and low-mid income countries
Bwititi, Phillip Taderera and Nwose, Ezekiel Ub. 2014. "Screening of cardiovascular disease risk in diabetes: Questions concerning prediabetes and low-mid income countries." North American Journal of Medical Sciences. 6 (6), pp. 45-47.
Adverse effects of zidovudine on rats vision: antioxidant and enzymology perspectives
Igbigbi, Patrick Sunday, Adjene, Josiah Obaghwarhievwo and Nwose, Ezekiel Uba. 2014. "Adverse effects of zidovudine on rats vision: antioxidant and enzymology perspectives." International Journal of Medical and Pharmaceutical Sciences. 4 (8), pp. 1-7. https://doi.org/10.13140/2.1.4303.9369
Cardiovascular Risks in Prediabetes: Preliminary Data on “Vasculopathy Triad”
Nwose, Ezekiel U, Richards, Ross S and Bwititi, Phillip T. 2014. "Cardiovascular Risks in Prediabetes: Preliminary Data on “Vasculopathy Triad” ." North American Journal of Medical Sciences. 6 (7), pp. 328-332.
Cardiovascular disease risk prevention: preliminary survey of baseline knowledge, attitude and practices of a Nigerian rural community
Oguoma, Victor Maduabuchi, Nwose, Ezekiel Uba and Bwititi, Philip Taderera. 2014. "Cardiovascular disease risk prevention: preliminary survey of baseline knowledge, attitude and practices of a Nigerian rural community." North American Journal of Medical Sciences. 6 (9), pp. 466-471. https://doi.org/10.4103/1947-2714.141644
Effects of anticoagulants on H2O2 levels in blood: comparison of citrate and EDTA
Chalada, Melissa J, Nwose, Ezekiel U and Bwititi, Phillip T. 2013. "Effects of anticoagulants on H2O2 levels in blood: comparison of citrate and EDTA." Australian Institute of Medical Scientists National Scientific Meeting 2013 (AIMS 2013). Melbourne, Australia 02 2013 - 04 Sep 2014 Australia.
Effects of zidovudine on auditory functions: enzymology and oxidative stress perspectives
Igbigbi, PS, Adjene, JO and Nwose, Ezekiel. 2013. "Effects of zidovudine on auditory functions: enzymology and oxidative stress perspectives." Diagnostic and Therapeutic Study. 2 (4), pp. 76-82.
Quality in diagnostic microbiology: Experiential note to emphasize value of internal control programs
Nwose, Ezekiel Uba. 2013. "Quality in diagnostic microbiology: Experiential note to emphasize value of internal control programs." North American Journal of Medical Sciences. 5 (2), pp. 82-87.
Blood Viscosity, Lipid Profile and Lipid Peroxidation in Type-1 Diabetic Patients with Good and Poor Glycemic Control: The Promise and Reality
Nwose, Ezekiel Uba. 2013. "Blood Viscosity, Lipid Profile and Lipid Peroxidation in Type-1 Diabetic Patients with Good and Poor Glycemic Control: The Promise and Reality ." North American Journal of Medical Sciences. 5 (9), pp. 567-568.
Algorithm for whole blood viscosity: Implication for antiplatelet bleeding risk assessment
Nwose, Ezekiel U. and Butkowski, Eugene G. 2013. "Algorithm for whole blood viscosity: Implication for antiplatelet bleeding risk assessment." Australian Journal of Medical Science. 34 (2), pp. 50-55.
Can Computer Meridian Diagnostic be useful in diagnosis and management of diseases?
Nwose, E.U. and Bwititi, P.T.. 2013. "Can Computer Meridian Diagnostic be useful in diagnosis and management of diseases?" Medical Hypotheses. 81 (4), pp. 564-567. https://doi.org/10.1016/j.mehy.2013.07.004
Reactive nitrogen and oxygen species in anticoagulated blood of healthy sheep
Nwose, Ezekiel Uba, Bwititi, Phillip Taderera and Chalada, Melissa Judith. 2013. "Reactive nitrogen and oxygen species in anticoagulated blood of healthy sheep." Expert Opinion on Medical Diagnostics. 7 (5), pp. 427-433. https://doi.org/10.1517/17530059.2013.808187
Oxidative stress research: a framework to relate basic science to clinical practice
Nwose, Ezekiel Uba, Bwititi, Phillip Taderera and Chalada, Melissa Judith.. 2013. "Oxidative stress research: a framework to relate basic science to clinical practice." Oxidants and Antioxidants in Medical Science. 2 (4), pp. 225-229.
New guidelines for diagnosis of gestational diabetes: Pathology-based impact assessment
Nwose, Ezekiel Uba, Richards, Ross Stuart, Bwititi, Phillip Taderera and Butkowski, Eugene George. 2013. "New guidelines for diagnosis of gestational diabetes: Pathology-based impact assessment." North American Journal of Medical Sciences. 5 (3), pp. 191-194. https://doi.org/10.4103/1947-2714.109184
Cardiovascular risk assessment in prediabetes and undiagnosed diabetes mellitus study: International collaboration research overview
Nwose, Ezekiel Uba, Richards, Ross Stuart, Digban, Kester, Bwititi, Philip Taderera, Ennis, Gretchen, Yee, Kwang Choon, Oguoma, Victor Maduabuchi and Liberato, Selma. 2013. "Cardiovascular risk assessment in prediabetes and undiagnosed diabetes mellitus study: International collaboration research overview." North American Journal of Medical Sciences. 5 (11), pp. 625-630.
Whole-blood viscosity and metabolic syndrome
Gyawali, Prajwal, Richards, Ross S, Nwose, Ezekiel Uba and Bwititi, Phillip T. 2012. "Whole-blood viscosity and metabolic syndrome ." Clinical Lipidology. 7 (6), pp. 709-719. https://doi.org/10.2217/CLP.12.65
Erythrocyte morphology in metabolic syndrome
Gyawali, Prajwal, Richards, Ross S. and Nwose, Ezekiel Uba. 2012. "Erythrocyte morphology in metabolic syndrome ." Expert Review of Hematology. 5 (5), pp. 523-531. https://doi.org/10.1586/EHM.12.47
Serum uric acid and albumin levels and estimated glomerular filtration rate: Oxidative stress considerations
Bwititi, Phillip, Nwose, Uba, Nielsen, Sharon, Ruven, Henk, Kalle, Wouter, Richards, Ross and Butkowski, Eugene. 2012. "Serum uric acid and albumin levels and estimated glomerular filtration rate: Oxidative stress considerations." Australian Journal of Medical Science. 33 (3), pp. 82-87.
Prevalence of anemia and risk of adverse bleeding effect of drugs: implication for therapy
Nwose, Ezekiel Uba. 2012. "Prevalence of anemia and risk of adverse bleeding effect of drugs: implication for therapy." Anemia. 2012. https://doi.org/10.1155/2012/795439
Serum bilirubin and lipoprotein-a: How are these associated with whole blood viscosity?
Nwose, E. U., Richards, R. S., Bwititi, P. and Butkowski, E.. 2012. "Serum bilirubin and lipoprotein-a: How are these associated with whole blood viscosity?" Redox Report. 17 (1), pp. 8-13. https://doi.org/10.1179/1351000211Y.0000000017
Prevalence of abnormal oral glucose tolerance with concomitant dyslipidaemia: Implications for cardiovascular risk assessment in prediabetes
Nwose, E. U., Richards, R. S. and Cann, N. C.. 2012. "Prevalence of abnormal oral glucose tolerance with concomitant dyslipidaemia: Implications for cardiovascular risk assessment in prediabetes." British Journal of Biomedical Science. 69 (3), pp. 97-98.
Histological effects of chronic administration of aqueous extract of Phyllanthus amarus on the stomach and the duodenum of Wistar rat
Adjene, J.O., Abudu, I.E. and Nwose, E.U.. 2011. "Histological effects of chronic administration of aqueous extract of Phyllanthus amarus on the stomach and the duodenum of Wistar rat." Electronic Journal of Biomedicine. 2011 (1), pp. 9-13.
Low serum creatinine levels as risk factor of diabetes mellitus: prediabetes considerations
Nwose, Ezekiel Uba, Bwititi, Phillip Taderera, Cann, NG and Butkowski, Eugene George. 2011. "Low serum creatinine levels as risk factor of diabetes mellitus: prediabetes considerations." African Journal of Medicine and Medical Sciences. 40 (2), pp. 119-122.
Whole blood viscosity extrapolation formula: Note on appropriateness of units
Nwose, Ezekiel Uba and Richards, Ross Stuart. 2011. "Whole blood viscosity extrapolation formula: Note on appropriateness of units." North American Journal of Medical Sciences. 3 (8), pp. 384-386.
Whole blood viscosity issue VIII: Comparison of extrapolation method with diagnostic digital viscometer
Nwose, Ezekiel Uba and Richards, Ross Stuart. 2011. "Whole blood viscosity issue VIII: Comparison of extrapolation method with diagnostic digital viscometer." North American Journal of Medical Sciences. 3 (7), pp. 333-335.
Biochemical basis of circadian rhythms and diseases: With emphasis on post-traumatic stress disorder
Richards, R.S., Nwose, E.U. and Bwititi, P.. 2011. "Biochemical basis of circadian rhythms and diseases: With emphasis on post-traumatic stress disorder." Medical Hypotheses. 77 (4), pp. 605-609. https://doi.org/10.1016/j.mehy.2011.06.045
Histological effects of chronic administration of efavirenz on lateral geniculate body of adult Wistar rats
Adjene, Josiah Obaghwarhievwo, Igbigbi, Patrick Sunday and Nwose, Ezekiel Uba. 2010. "Histological effects of chronic administration of efavirenz on lateral geniculate body of adult Wistar rats." North American Journal of Medical Sciences. 2 (1), pp. 1-4. https://doi.org/10.4297/najms.2010.11
Histological effects of long term consumption of nutmeg on the medial geniculate body of adult Wistar rats
Adjene, Josiah Obaghwarhievwo and Nwose, Ezekiel Uba. 2010. "Histological effects of long term consumption of nutmeg on the medial geniculate body of adult Wistar rats." North American Journal of Medical Sciences. 2 (3), pp. 134-137.
Histological effects of chronic administration of Phyllanthus amarus on the kidney of adult Wistar rat
Adjene, Josiah Obaghwarhievwo and Nwose, Ezekiel Uba. 2010. "Histological effects of chronic administration of Phyllanthus amarus on the kidney of adult Wistar rat." North American Journal of Medical Sciences. 2 (4), pp. 193-195. https://doi.org/10.4297/najms.2010.2193
Histological effects of chronic consumption of soda pop drinks on kidney of adult Wister rats
Adjene, Josiah Obaghwarhievwo, Ezeoke, Joseph Chigozie and Nwose, Ezekiel Uba. 2010. "Histological effects of chronic consumption of soda pop drinks on kidney of adult Wister rats." North American Journal of Medical Sciences. 2 (5), pp. 215-217.
Cardiovascular risk assessment and support - Whole blood viscosity assessment issues I: Extrapolation chart and reference values
Nwose, Ezekiel Uba. 2010. "Cardiovascular risk assessment and support - Whole blood viscosity assessment issues I: Extrapolation chart and reference values." North American Journal of Medical Sciences. 2 (4), pp. 165-169.
Whole blood viscosity assessment issues II: prevalence in endothelial dysfunction and hypercoagulation
Nwose, Ezekiel Uba. 2010. "Whole blood viscosity assessment issues II: prevalence in endothelial dysfunction and hypercoagulation." North American Journal of Medical Sciences. 2 (6), pp. 252-257.
Whole blood viscosity assessment issues IV: Prevalence in acute phase inflammation
Nwose, Ezekiel Uba. 2010. "Whole blood viscosity assessment issues IV: Prevalence in acute phase inflammation." North American Journal of Medical Sciences. 2 (8), pp. 353-358.
Oxidative Stress Concepts in Clinical Practice: Towards optimizing medical nutrition therapy with laboratory methods
Nwose, Ezekiel Uba. 2010. Oxidative Stress Concepts in Clinical Practice: Towards optimizing medical nutrition therapy with laboratory methods. Germany. LAP LAMBERT Academic Publishing.
Whole blood viscosity assessment issues V: Prevalence in hypercreatinaemia, hyperglycaemia and hyperlipidaemia
Nwose, Ezekiel Uba. 2010. "Whole blood viscosity assessment issues V: Prevalence in hypercreatinaemia, hyperglycaemia and hyperlipidaemia." North American Journal of Medical Sciences. 2 (9), pp. 403-408.
Whole blood viscosity issues VI: Association with blood salicylate level and gastrointestinal bleeding
Nwose, Ezekiel Uba and Cann, Nathan. 2010. "Whole blood viscosity issues VI: Association with blood salicylate level and gastrointestinal bleeding." North American Journal of Medical Sciences. 2 (10), pp. 457-460.
Using laboratory data to audit compliance to clinical guidelines: focus on antioxidant and antiplatelet therapies
Nwose, Ezekiel Uba, Cann, Nathan and Butkowski, Eugene. 2010. "Using laboratory data to audit compliance to clinical guidelines: focus on antioxidant and antiplatelet therapies." 19th Annual Scientific Meeting of Australasian Health and Research Data Manager’s Association (AHRDMA).
Whole blood viscosity assessment issues III: Association with international normalized ratio and thrombocytopenia
Nwose, Ezekiel Uba, Cann, Nathan and Butkowski, Eugene. 2010. "Whole blood viscosity assessment issues III: Association with international normalized ratio and thrombocytopenia." North American Journal of Medical Sciences. 2 (7), pp. 301-305.
Whole blood viscosity issues VII: the correlation with leucocytosis and implication on leukapheresis
Nwose, Ezekiel Ub and Richards, Ross Stuart. 2010. "Whole blood viscosity issues VII: the correlation with leucocytosis and implication on leukapheresis." North American Journal of Medical Sciences. 2 (12), pp. 576-579.
Position paper for health authorities: archived clinical pathology data - treasure to revalue and appropriate
Nwose, EU, Richards, RS, Butkowski, E and Cann, N. 2010. "Position paper for health authorities: archived clinical pathology data - treasure to revalue and appropriate." African Journal of Medicine and Medical Sciences. 39 (4), pp. 311-315.
Assessment of diabetic macrovascular complications: a prediabetes model
Nwose, E.U., Richards, R.S., McDonald, S., Jelinek, H. F., Kerr, P.G. and Tinley, P.. 2010. "Assessment of diabetic macrovascular complications: a prediabetes model." British Journal of Biomedical Science. 67 (2), pp. 59-66. https://doi.org/10.1080/09674845.2010.11730292
Blood viscosity at different stages of diabetes pathogenesis
Richards, R. S. and Nwose, E. U.. 2010. "Blood viscosity at different stages of diabetes pathogenesis." British Journal of Biomedical Science. 67 (2), pp. 67-70. https://doi.org/10.1080/09674845.2010.11730293
Obstructive sleep apnea management with interactive computer technology and nutrition: Two case reports
Ewing, Graham W., Nwose, Ezekiel U. and Ewing, Elena N.. 2009. "Obstructive sleep apnea management with interactive computer technology and nutrition: Two case reports." Journal of Alternative and Complementary Medicine. 15 (12), pp. 1379-1381. https://doi.org/10.1089/acm.2008.0630
Pepper soup as an antioxidant nutrition therapy
Nwose, Ezekiel U.. 2009. "Pepper soup as an antioxidant nutrition therapy." Medical Hypotheses. 73 (5), pp. 860-861. https://doi.org/10.1016/j.mehy.2009.04.016
Laboratory evaluations to optimize outcomes of antioxidant nutrition therapy in diabetes management
Nwose, Ezekiel Uba. 2009. "Laboratory evaluations to optimize outcomes of antioxidant nutrition therapy in diabetes management." North American Journal of Medical Sciences. 1 (3), pp. 137-143.
Whole blood viscosity determination in diabetes management: perspective in practice
Nwose, Ezekiel Uba, Butkowski, Eugene and Cann, Nathan. 2009. "Whole blood viscosity determination in diabetes management: perspective in practice." North American Journal of Medical Sciences. 1 (3), pp. 110-113.
Coagulase-negative Staphylococcus bacteraemia evaluation: lack of clinical information and prevalence of methicillin resistance
Nwose, Ezekiel, Cann, Nathan and Jha, Gangesh. 2009. "Coagulase-negative Staphylococcus bacteraemia evaluation: lack of clinical information and prevalence of methicillin resistance." Australian Journal of Medical Science. 30 (2), pp. 52-55.
Computer diagnosis in cardiology: oxidative stress hypothesis
Nwose, Ezekiel Uba and Ewing, Graham Wilfred. 2009. "Computer diagnosis in cardiology: oxidative stress hypothesis." North American Journal of Medical Sciences. 1 (5), pp. 220-225.
Migraine can be managed with Virtual Scanning: case report
Ewing, E., Ewing, G. and Nwose, E.U.. 2009. "Migraine can be managed with Virtual Scanning: case report." The Open Complementary Medicine Journal. 1, pp. 16-18. https://doi.org/10.2174/1876391X00901010016
Atherothrombosis and oxidative stress: The connection and correlation in diabetes
Nwose, Ezekiel U, Jelinek, Herbert F., Richards, Ross S., Tinley, Paul and Kerr, Philip G.. 2009. "Atherothrombosis and oxidative stress: The connection and correlation in diabetes." Redox Report. 14 (2), pp. 55-60. https://doi.org/10.1179/135100009X392458
Management of stress and stress-related diseases: Emerging computer-based technologies and the rationale for clinical laboratory assessment
Nwose, Ezekiel Uba and Richards, Ross Stuart. 2009. "Management of stress and stress-related diseases: Emerging computer-based technologies and the rationale for clinical laboratory assessment." North American Journal of Medical Sciences. 1 (6), pp. 288-294.
Cardiovascular risk assessment in prediabetes: A hypothesis
Nwose, E.U., Richards, R.S., Cann, N.G. and Butkowski, E.. 2009. "Cardiovascular risk assessment in prediabetes: A hypothesis." Medical Hypotheses. 72 (3), pp. 271-275. https://doi.org/10.1016/j.mehy.2008.07.063
Virtual Scanning technology – the relationship to oxidative stress and applicability to diabetes management
Ewin, G.W., Ewing, E.N. and Nwose, E.U.. 2008. "Virtual Scanning technology – the relationship to oxidative stress and applicability to diabetes management." Biogenic Amines. 22 (4-5), pp. 201-213.
Chemical immunology and allergy - Volume 93, superantigens and superallergens by G MaroneS and Karger AG
Nwose, E Uba. 2008. "Chemical immunology and allergy - Volume 93, superantigens and superallergens by G MaroneS and Karger AG." Australian Journal of Medical Science. 29 (2), pp. 59-59.
The ‘vitamin E regeneration system’ (VERS) and an algorithm to justify antioxidant supplementation in diabetes – A hypothesis
Nwose, Ezekiel U., Jelinek, Herbert F., Richards, Ross S. and Kerr, Philip G.. 2008. "The ‘vitamin E regeneration system’ (VERS) and an algorithm to justify antioxidant supplementation in diabetes – A hypothesis ." Medical Hypotheses. 70 (5), pp. 1002-1008. https://doi.org/10.1016/j.mehy.2007.07.048
Oxidative damage indices for the assessment of subclinical diabetic macrovascular complications
Nwose, E.U., Richards, R.S., Kerr, P.G., Tinley, P. and Jelinek, H.. 2008. "Oxidative damage indices for the assessment of subclinical diabetic macrovascular complications." British Journal of Biomedical Science. 65 (3), pp. 136-141. https://doi.org/10.1080/09674845.2008.11732817
Chromogenic methicillin-resistant Staphylococcus aureus media: Notice of two types of false positive morphologies
Nwose, Ezekiel, Veneris, Koula, Pearce, Marlene, Jha, Gangesh, Murphy, Joanne and Robb, David. 2008. "Chromogenic methicillin-resistant Staphylococcus aureus media: Notice of two types of false positive morphologies." Australian Journal of Medical Science. 29 (2), pp. 50-53.
Oxidative stress and related cardiovascular events: Biomarkers improve CAD screening in prediabetes
Nwose, E. U., Jelinek, H.F., Richards, R.S. and Kerr, P.G.. 2007. "Oxidative stress and related cardiovascular events: Biomarkers improve CAD screening in prediabetes ." Free Radical Research. 40 (S1), pp. S142-S142.
Changes in oxidative stress markers during the progression of diabetes mellitus
Nwose, E.U., Jelinek, H.F., Richards, R.S. and Kerr, P.G.. 2007. "Changes in oxidative stress markers during the progression of diabetes mellitus ." Free Radical Research. 40 (S1), pp. S138-S138.
D-dimer level in diabetes mellitus is correlated with oxidative stress status 'in vivo'
Nwose, E.U., Jelinek, H.F., Richards, R.S. and Kerr, P.G.. 2007. "D-dimer level in diabetes mellitus is correlated with oxidative stress status 'in vivo' ." Free Radical Research. 40 (S1), pp. S137-S137.
Vitamin E supplementation: A question
Nwose, E.U., Jelinek, H.F., Richards, R.S. and Kerr, P.G.. 2007. "Vitamin E supplementation: A question ." Free Radical Research. 40 (S1), pp. S116-S116.
The Lancet Handbook of Essential Concepts in Clinical Research by by Kenneth F Scholz and David A Grimes
Nwose, E Uba. 2007. "The Lancet Handbook of Essential Concepts in Clinical Research by by Kenneth F Scholz and David A Grimes." Australian Journal of Medical Science. 28 (3), pp. 128-129.
Erratum: Changes in the erythrocyte glutathione concentration in the course of diabetes mellitus
Nwose, Ezekiel U., Jelinek, Herbert F., Richards, Ross S. and Kerr, P.G.. 2007. "Erratum: Changes in the erythrocyte glutathione concentration in the course of diabetes mellitus." Redox Report. 12 (3), pp. 162-162. https://doi.org/10.1179/135100007X200236
Erythrocyte oxidative stress in clinical management of diabetes and its cardiovascular complications
Nwose, E. U., Jelinek, H. F., Richards, R. S. and Kerr, P. G.. 2007. "Erythrocyte oxidative stress in clinical management of diabetes and its cardiovascular complications ." British Journal of Biomedical Science. 64 (1), pp. 35-43. https://doi.org/10.1080/09674845.2007.11732754
D-dimer identifies stages in the progression of diabetes mellitus from family history of diabetes to cardiovascular complications
Nwose, Ezekiel U., Richards, Ross S., Jelinek, Herbert F. and Kerr, Philip G.. 2007. "D-dimer identifies stages in the progression of diabetes mellitus from family history of diabetes to cardiovascular complications." Pathology. 39 (2), pp. 252-257. https://doi.org/10.1080/00313020701230658
Changes in the erythrocyte glutathione concentration in the course of diabetes mellitus
Nwose, Ezekiel U., Jelinek, Herbert F., Richards, Ross S. and Kerr, P.G.. 2006. "Changes in the erythrocyte glutathione concentration in the course of diabetes mellitus." Redox Report. 11 (3), pp. 99-104. https://doi.org/10.1179/135100006x116583