Cardiovascular Risk Assessment in Pre-Diabetes: A Hypothesis A2 - Watson, Ronald Ross
Edited book (chapter)
Nwose, Ezekiel Uba. 2015. "Cardiovascular Risk Assessment in Pre-Diabetes: A Hypothesis A2 - Watson, Ronald Ross." Watson, Ronald Ross and Dokken, Betsy B. (ed.) Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular Disease. United States. Academic Press. pp. 103-117
Chapter Title | Cardiovascular Risk Assessment in Pre-Diabetes: A Hypothesis A2 - Watson, Ronald Ross |
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Book Chapter Category | Edited book (chapter) |
ERA Publisher ID | 1034 |
Book Title | Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular Disease |
Authors | Nwose, Ezekiel Uba |
Editors | Watson, Ronald Ross and Dokken, Betsy B. |
Page Range | 103-117 |
Chapter Number | 9 |
Number of Pages | 15 |
Year | 2015 |
Publisher | Academic Press |
Place of Publication | United States |
ISBN | 9780128000939 |
Digital Object Identifier (DOI) | https://doi.org/10.1016/B978-0-12-800093-9.00009-0 |
Web Address (URL) | http://www.sciencedirect.com/science/article/pii/B9780128000939000090 |
Abstract | There are screening programs for future risk of cardiovascular disease (CVD) complications in diabetes, but not in subclinical diabetes. In the current screening programs, a hypothetical apparently non-diabetic and nonsmoking 40-year-old single parent, from a low- to middle-income community, with a problem of access or affordability of lipid profile, who has blood pressure=120/80 mmHg, fasting blood sugar 5.8 mmol/L, and total cholesterol/HDL=6.5, has no risk of future CVD and does not require any intervention. On counting numbers, the person has two risk factors, that is, hyperglycemia and hyperlipidemia. Further, considering single parenting as a stress factor, for which there is the propensity for underlying oxidative stress that would feed forward to oxidative damage, the person actually has three risk factors. Thus the person qualifies for intervention. The issue is that a pre-diabetes sufferer is treated like a healthy person in the current screening programs. This chapter revisits a previously published hypothesis that suggests a combination of blood glucose level and an index of oxidative damage to improve CVD screening in pre-diabetes. Significant improvement has occurred on the Framingham and the New Zealand Guidelines Group models. This update is meant to emphasize the need to develop a separate model chart for the screening of CVD risk in people with pre-diabetes or undiagnosed diabetes. |
Keywords | Clinical pathology |
Contains Sensitive Content | Does not contain sensitive content |
ANZSRC Field of Research 2020 | 420605. Preventative health care |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | Charles Sturt University |
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