Dr Asha Mathew


Dr Asha Mathew
NameDr Asha Mathew
Email Addressasha.mathew@unisq.edu.au
Job TitleVice-Chancellor's Postdoctoral Research Fellow For Women In STEMM
QualificationsBTech Mahatma Gandhi, MEng (Polymer) BIT, PhD NUI
DepartmentSchool of Engineering
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Biography

Dr Asha Mathew is a Vice-Chancellor Postdoctoral Research Fellow for Women in STEMM discipline at the University of Southern Queensland (UniSQ). Dr Asha Mathew has 10 years of experience in the field of biomaterials, especially in the area of bio-fabrication, drug delivery, antibiotic coating on polymeric scaffolds, developing antimicrobial nano-textured surfaces on 3D printed metallic and polymeric implants and for other industrial applications. Asha began her research career completing a master's degree project work in Prof Abhay Pandit’s Laboratory at National University of Ireland, Galway (NUIG). Upon acquiring the prestigious Irish Research Council for Science, Engineering and Technology (IRCSET) PhD scholarship, Asha pursued her PhD within Prof Pandit’s group at NUIG. Primary focus of her PhD was to develop a novel ex-vivo model multiple sclerosis (MS) using non-viral gene delivery approach. Upon completing her PhD in 2013, Asha worked as a postdoctoral research fellows Griffith University and Queensland University of Technology (QUT). Asha was awarded Advance Queensland Industry Research Fellowship (AQIRF) in 2019 for developing antimicrobial surfaces for 3D printed personalized orthopedic and soft tissue implants.

Employment

PositionOrganisationFromTo
Vice-Chancellor's Postdoctoral Research FellowUniversity of Southern Queensland2023
Research FellowsQueensland University of Technology20162023
Research FellowGriffith University20132015

Expertise

Drug/antibiotic delivery

Antimicrobial surface modification

Fields of Research

  • 401805. Nanofabrication, growth and self assembly
  • 401806. Nanomanufacturing
  • 401810. Nanoscale characterisation
  • 401899. Nanotechnology not elsewhere classified
BTech
Mahatma Gandhi
2006
MEng (Polymer)
BIT
2008
PhD
NUI
2013

Current Supervisions

Research TitleSupervisor TypeLevel of StudyCommenced
Enhancing the overall bactericidal efficacy of nanostructured surface against biofilm producers using native Australian medicinal plant-based moleculeAssociate SupervisorDoctoral2023
Methods for Development of Bactericidal Nanostructured Polymer SurfacesAssociate SupervisorDoctoral2023

Completed Supervisions

Research TitleSupervisor TypeLevel of StudyCompleted
Effect of fluid flow on bacterial attachment, detachment, and viability on nanostructured surfacesAssociateDoctoral2022
Project titleDetailsYear
MMPE ECR Catalyst GrantAmount awarded: $20,000, Role: Principal Investigator2022
Australia-India Strategic Research Fund (AISRF)Amount awarded: $479,362.00, Role: Australian Project Co-Investigator 2021
Women's Research Assistance Program Application (WRAP)Amount awarded:$20,800, Role: Principal Investigator2021
Advanced Queensland Industry Research FellowshipAmount awarded:359,166.67, Role: Principal Investigator2018
IHBI Early Career Research Development SchemeAmount awarded: $9882, Role: Principal Investigator2017
Australian Dental Research Foundation (ADRF)Amount awarded: $10,528.50, Role: Principal Investigator2017
Griffith University New Research GrantAmount awarded:$14000, Role: Principal Investigator2015
DOH Research GrantAmount awarded: $6000, Role: Principal Investigator2015
NUIG Enterprise Ireland InnovationAmount awarded: €5000, Role: Principal Investigator2011

Nano-roughness Modification of 3D printed Poly (lactic Acid) Polymer via Alkaline Wet Etching Towards Biomedical Applications

Kumara, S. P. S. N Buddhika Sampath, Senevirathne, S. W. M. A. Ishantha, Mathew, Asha, Ebenezer, Preetha, Yarlagadda, Tejasri, Bray, Laura, Mirkhalaf, Mohammad and Yarlagadda, Prasad K. D. V.. 2024. "Nano-roughness Modification of 3D printed Poly (lactic Acid) Polymer via Alkaline Wet Etching Towards Biomedical Applications." Journal of Applied Science and Engineering. 28 (6), pp. 1331-1340. https://doi.org/org/10.6180/jase.202506_28(6).0015

Progress in Nanostructured Mechano-Bactericidal Polymeric Surfaces for Biomedical Applications

Kumara, S. P. S. N. Buddhika Sampath, Senevirathne, S. W. M. Amal Ishantha, Mathew, Asha, Bray, Laura, Mirkhalaf, Mohammad and Yarlagadda, Prasad K.D.V.. 2023. "Progress in Nanostructured Mechano-Bactericidal Polymeric Surfaces for Biomedical Applications." Nanomaterials. 13 (20). https://doi.org/10.3390/nano13202799

Preferential adhesion of bacterial cells onto top- and bottom-mounted nanostructured surfaces under flow conditions

Senevirathne, S. W. M. A. Ishantha, Mathew, Asha, Toh, Yi Chin and Yarlagadda, Prasad K. D. V.. 2023. "Preferential adhesion of bacterial cells onto top- and bottom-mounted nanostructured surfaces under flow conditions." Nanoscale Advances. 5 (23). https://doi.org/10.1039/d3na00581j

Improving Infection Resistance in Tissue Engineered Scaffolds for Tensile Applications Using Vancomycin-Embedded Melt Electrowritten Scaffolds

Mathew, Asha, Devlin, Brenna L., Singh, Dilpreet, Paxton, Naomi C. and Woodruff, Maria A.. 2023. "Improving Infection Resistance in Tissue Engineered Scaffolds for Tensile Applications Using Vancomycin-Embedded Melt Electrowritten Scaffolds." Macromolecular Materials and Engineering. 308 (10). https://doi.org/10.1002/mame.202300168

Nanospikes on Customized 3D-Printed Titanium Implant Surface Inhibits Bacterial Colonization

Mathew, Asha, Hasan, Jafar, Singamneni, Sarat and Yarlagadda, Prasad K. D. V.. 2023. "Nanospikes on Customized 3D-Printed Titanium Implant Surface Inhibits Bacterial Colonization." Advanced Engineering Materials. 25 (8). https://doi.org/10.1002/adem.202201306

Bactericidal Efficacy of Nanostructured Surfaces Increases under Flow Conditions

Senevirathne, S. W. M. A. Ishantha, Mathew, Asha, Toh, Yi-Chin and Yarlagadda, Prasad K. D. V.. 2022. "Bactericidal Efficacy of Nanostructured Surfaces Increases under Flow Conditions ." ACS Omega. 7 (45), p. 41711–41722. https://doi.org/10.1021/acsomega.2c05828

The Significance of Coordinated Research Against SARS-CoV-2

Hasan, Jafar, Velic, Amar, Jaggessar, Alka, Mathew, Asha, Yarlagadda, Tejasri, Spann, Kirsten, Ramarishna, Seeram and Yarlagadda, Prasad K. D. V.. 2022. "The Significance of Coordinated Research Against SARS-CoV-2." Batako, Andre, Burduk, Anna, Karyono, Kanisius, Chen, Xun and Wyczólkowski, Ryszard (ed.) 15 th Global Congress on Manufacturing and Management (GCMM 2021). Liverpool, United Kingdom 20 - 23 Apr 2021 Switzerland. https://doi.org/10.1007/978-3-030-90532-3_53

Trends in Bactericidal Nanostructured Surfaces: An Analytical Perspective

Senevirathne, S. W. M. A. Ishantha, Hasan, Jafar, Mathew, Asha, Jaggessar, Alka and Yarlagadda, Prasad K.D.V.. 2021. "Trends in Bactericidal Nanostructured Surfaces: An Analytical Perspective ." ACS Applied Bio Materials. 4 (10), pp. 7626-7642. https://doi.org/10.1021/acsabm.1c00839

Bactericidal efficiency of micro- and nanostructured surfaces: a critical perspective

Senevirathne, S. W. M. A. I., Hasan, J., Mathew, A., Woodruff, M. and Yarlagadda, P. K. D. V.. 2021. "Bactericidal efficiency of micro- and nanostructured surfaces: a critical perspective ." RSC Advances: an international journal to further the chemical sciences. 11 (3), pp. 1883-1900. https://doi.org/10.1039/d0ra08878a

Adaptations and lessons from COVID-19: A perspective on how some industries will be impacted

Velic, Amar, Jaggessar, Alka, Senevirathne, Amal, Mathew, Asha, Paritala, Paritala, Phani, Islam, Majedul, Panicker, Arpana Gopi, Prasad, Karthika, Yarlagadda, Teja, Spann, Kirsten, Hasan, Jafar and Yarlagadda, Prasad K. D. V.. 2020. "Adaptations and lessons from COVID-19: A perspective on how some industries will be impacted." Advanced Materials Letter. 11 (7). https://doi.org/10.5185/amlett.2020.071533

Bacteria Death and Osteoblast Metabolic Activity Correlated to Hydrothermally Synthesised TiO2 Surface Properties

Jaggessar, Alka, Mathew, Asha, Tesfamichael, Tuquabo, Wang, Hongxia, Yan, Cheng and Yarlagadda, Prasad KDV. 2019. "Bacteria Death and Osteoblast Metabolic Activity Correlated to Hydrothermally Synthesised TiO2 Surface Properties ." Molecules. 24 (7). https://doi.org/10.3390/molecules24071201

Multi-biofunctional properties of three species of cicada wings and biomimetic fabrication of nanopatterned titanium pillars

Shahali, Hesam, Hasan, Jafar, Mathew, Asha, Wang, Hongxia, Yan, Cheng, Tesfamichael, Tuquabo, Yarlagadda, Prasad K. D. V. and Murray, P.. 2019. "Multi-biofunctional properties of three species of cicada wings and biomimetic fabrication of nanopatterned titanium pillars." Journal of Materials Chemistry B. 7 (8), pp. 1300-1310. https://doi.org/10.1039/c8tb03295e

Control of bacterial attachment by fracture topography

Velic, Amar, Mathew, Asha, Hines, Peter and Yarlagadda, Prasad K.D.V.. 2019. "Control of bacterial attachment by fracture topography ." Journal of The Mechanical Behavior of Biomedical Materials. 91, pp. 416-424. https://doi.org/10.1016/j.jmbbm.2018.10.020

Mechanical, bactericidal and osteogenic behaviours of hydrothermally synthesised TiO2 nanowire arrays

Jaggessar, Alka, Mathew, Asha, Wang, Hongxia, Tesfamichael, Tuquabo, Yan, Cheng and Yarlagadda, Prasad KDV. 2018. "Mechanical, bactericidal and osteogenic behaviours of hydrothermally synthesised TiO2 nanowire arrays ." Journal of The Mechanical Behavior of Biomedical Materials. 80, pp. 311-319. https://doi.org/10.1016/j.jmbbm.2018.02.011

Bio-mimicking nano and micro-structured surface fabrication for antibacterial properties in medical implants

Jaggessar, Alka, Shahali, Hesam, Mathew, Asha and Yarlagadda, Prasad K. D. V.. 2017. "Bio-mimicking nano and micro-structured surface fabrication for antibacterial properties in medical implants ." Journal of Nanobiotechnology. 15, pp. 1-20. https://doi.org/10.1186/s12951-017-0306-1

Antimicrobial and immunomodulatory surface-functionalized electrospun membranes for bone regeneration

Mathew, Asha, Vaquette, Cedryck, Hashimi, Saeed, Rathnayake, Irani, Huygens, Flavia, Hutmacher, Dietmar and Ivanovski, Saso. 2017. "Antimicrobial and immunomodulatory surface-functionalized electrospun membranes for bone regeneration." Advanced Healthcare Materials. 6 (10). https://doi.org/10.1002/adhm.201601345

Cationic polymers in the central nervous system: Past, present and future

Mathew, Asha, Morey, Mangesh and Pandit, Abhay. 2015. "Cationic polymers in the central nervous system: Past, present and future." Samal, Sangram K. and Dubruel, Peter (ed.) Cationic polymers in Regenerative medicine. United Kingdom. Royal Society of Chemistry (RSC). pp. 463-478

Periodontal tissue graft

Farag, Amro, Mathew, Asha, Vaquette, Cedryck, Hutmacher, Dietmar and Ivanovski, Saso. 2014. Periodontal tissue graft. AU2014903870

An ex-vivo multiple sclerosis model of inflammatory demyelination using hyperbranched polymer

Mathew, Asha, Pakan, Janelle M.P., Collin, Estelle C., Wang, Wenxin, McDermott, Kieran W., Fitzgerald, Una, Reynolds, Richard and Pandit, Abhay S.. 2013. "An ex-vivo multiple sclerosis model of inflammatory demyelination using hyperbranched polymer." Biomaterials. 34 (23), pp. 5872-5882. https://doi.org/10.1016/j.biomaterials.2013.04.010

Transfection of macrophages by collagen hollow spheres loaded with polyplexes: A step towards modulating inflammation

Helary, Christophe, Browne, Shane, Mathew, Asha, Wang, Wenxin and Pandit, Pandit. 2012. "Transfection of macrophages by collagen hollow spheres loaded with polyplexes: A step towards modulating inflammation." Acta Biomaterialia. 8 (12), pp. 4208-4214. https://doi.org/10.1016/j.actbio.2012.06.017

Hyperbranched PEGmethacrylate linear pDMAEMA block copolymer as an efficient non-viral gene delivery vector

Mathew, Asha, Cao, Hongliang, Collin, Estelle, Wang, Wenxin and Pandit, Abhay. 2012. "Hyperbranched PEGmethacrylate linear pDMAEMA block copolymer as an efficient non-viral gene delivery vector." International Journal of Pharmaceutics. 434 (1-2), pp. 99-105. https://doi.org/10.1016/j.ijpharm.2012.05.010

Tunable elastin-like polypeptide hollow sphere as a high payload and controlled delivery gene depot

Dash, Biraja C., Mahor, Sunil, Carroll, Oliver, Mathew, Asha, Wang, Wenxin, Woodhouse, Kimberly A. and Pandit, Abhay. 2011. "Tunable elastin-like polypeptide hollow sphere as a high payload and controlled delivery gene depot." Journal of Controlled Release. 152 (3), pp. 382-392. https://doi.org/10.1016/j.jconrel.2011.03.006

Dual stimuli responsive PEG based hyperbranched polymers

Dong, Yixiao, Gunning, Paul, Cao, Hongliang, Mathew, Asha, Newland, Ben, Saeed, Aram Omer, Magnusson, Johannes Pall, Alexander, Cameron, Tai, Hongyun, Pandit, Abhay and Wang, Wenxin. 2010. "Dual stimuli responsive PEG based hyperbranched polymers." Polymer Chemistry. 1 (6), pp. 827-830. https://doi.org/10.1039/c0py00101e

Preparation of chitosan/polyglutamic acid spheres based on the use of polystyrene template as a nonviral gene carrier

Réthoré, Gildas, Mathew, Asha, Naik, Hemantkumar and Pandit, Abhay. 2009. "Preparation of chitosan/polyglutamic acid spheres based on the use of polystyrene template as a nonviral gene carrier." Tissue Engineering Part C: Methods. 15 (4), pp. 605-613. https://doi.org/10.1089/ten.tec.2008.0581