Bactericidal efficiency of micro- and nanostructured surfaces: a critical perspective
Article
Article Title | Bactericidal efficiency of micro- and nanostructured surfaces: a critical perspective |
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ERA Journal ID | 201472 |
Article Category | Article |
Authors | Senevirathne, S. W. M. A. I., Hasan, J., Mathew, A., Woodruff, M. and Yarlagadda, P. K. D. V. |
Journal Title | RSC Advances: an international journal to further the chemical sciences |
Journal Citation | 11 (3), pp. 1883-1900 |
Number of Pages | 18 |
Year | 2021 |
Publisher | The Royal Society of Chemistry |
Place of Publication | United Kingdom |
ISSN | 2046-2069 |
Digital Object Identifier (DOI) | https://doi.org/10.1039/d0ra08878a |
Web Address (URL) | https://pubs.rsc.org/en/content/articlelanding/2021/RA/D0RA08878A |
Abstract | Micro/nanostructured surfaces (MNSS) have shown the ability to inactivate bacterial cells by physical means. An enormous amount of research has been conducted in this area over the past decade. Here, we review the various surface factors that affect the bactericidal efficiency. For example, surface hydrophobicity of the substrate has been accepted to be influential on the bactericidal effect of the surface, but a review of the literature suggests that the influence of hydrophobicity differs with the bacterial species. Also, various bacterial viability quantification methods on MNSS are critically reviewed for their suitability for the purpose, and limitations of currently used protocols are discussed. Presently used static bacterial viability assays do not represent the conditions of which those surfaces could be applied. Such application conditions do have overlaying fluid flow, and bacterial behaviours are drastically different under flow conditions compared to under static conditions. Hence, it is proposed that the bactericidal effect should be assessed under relevant fluid flow conditions with factors such as shear stress and flowrate given due significance. This review will provide a range of opportunities for future research in design and engineering of micro/nanostructured surfaces with varying experimental conditions. |
Keywords | Micro/nanostructured surfaces (MNSS); bactericidal effect |
ANZSRC Field of Research 2020 | 4003. Biomedical engineering |
Byline Affiliations | Queensland University of Technology |
https://research.usq.edu.au/item/y1862/bactericidal-efficiency-of-micro-and-nanostructured-surfaces-a-critical-perspective
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