Bacterial adherence and biofilm formation on medical implants: A review
Article
Article Title | Bacterial adherence and biofilm formation on medical implants: A review |
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ERA Journal ID | 5059 |
Article Category | Article |
Authors | Veerachamy, Suganthan, Yarlagadda, Tejasri, Manivasagam, Geetha and Yarlagadda, Prasad K. D. V. |
Journal Title | Proceedings of the Institution of Mechanical Engineers Part H: Journal of Engineering in Medicine |
Journal Citation | 228 (10), pp. 1083-1099 |
Number of Pages | 17 |
Year | Oct 2014 |
Place of Publication | United Kingdom |
ISSN | 0954-4119 |
Digital Object Identifier (DOI) | https://doi.org/10.1177/0954411914556137 |
Web Address (URL) | https://journals.sagepub.com/doi/10.1177/0954411914556137 |
Abstract | Biofilms are a complex group of microbial cells that adhere to the exopolysaccharide matrix present on the surface of medical devices. Biofilm-associated infections in the medical devices pose a serious problem to the public health and adversely affect the function of the device. Medical implants used in oral and orthopedic surgery are fabricated using alloys such as stainless steel and titanium. The biological behavior, such as osseointegration and its antibacterial activity, essentially depends on both the chemical composition and the morphology of the surface of the device. Surface treatment of medical implants by various physical and chemical techniques are attempted in order to improve their surface properties so as to facilitate bio-integration and prevent bacterial adhesion. The potential source of infection of the surrounding tissue and antimicrobial strategies are from bacteria adherent to or in a biofilm on the implant which should prevent both biofilm formation and tissue colonization. This article provides an overview of bacterial biofilm formation and methods adopted for the inhibition of bacterial adhesion on medical implants. |
Keywords | Biofilm; bacteria; medical implants; infections; nano-polymer coatings |
Contains Sensitive Content | Does not contain sensitive content |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | VIT University, India |
Newcastle University of Medicine, Malaysia | |
Queensland University of Technology |
https://research.usq.edu.au/item/w457q/bacterial-adherence-and-biofilm-formation-on-medical-implants-a-review
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