Trends in Bactericidal Nanostructured Surfaces: An Analytical Perspective
Article
Article Title | Trends in Bactericidal Nanostructured Surfaces: An Analytical Perspective |
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ERA Journal ID | 211581 |
Article Category | Article |
Authors | Senevirathne, S. W. M. A. Ishantha, Hasan, Jafar, Mathew, Asha, Jaggessar, Alka and Yarlagadda, Prasad K.D.V. |
Journal Title | ACS Applied Bio Materials |
Journal Citation | 4 (10), pp. 7626-7642 |
Number of Pages | 17 |
Year | 2021 |
Publisher | American Chemical Society |
Place of Publication | United States |
ISSN | 2576-6422 |
Digital Object Identifier (DOI) | https://doi.org/10.1021/acsabm.1c00839 |
Web Address (URL) | https://pubs.acs.org/doi/10.1021/acsabm.1c00839# |
Abstract | Since the discovery of the bactericidal properties of cicada wing surfaces, there has been a surge in the number of studies involving antibacterial nanostructured surfaces (NSS). Studies show that there are many parameters (and thus, thousands of parameter combinations) that influence the bactericidal efficiency (BE) of these surfaces. Researchers attempted to correlate these parameters to BE but have so far been unsuccessful. This paper presents a meta-analysis and perspective on bactericidal NSS, aiming to identify trends and gaps in the literature and to provide insights for future research. We have attempted to synthesize data from a wide range of published studies and establish trends in the literature on bactericidal NSS. Numerous research gaps and findings based on correlations of various parameters are presented here, which will assist in the design of efficient bactericidal NSS and shape future research. Traditionally, it is accepted that BE of NSS depends on the bacterial Gram-stain type. However, this review found that factors beyond Gram-stain type are also influential. Furthermore, it is found that despite their higher BE, hydrophobic NSS are less commonly studied for their bactericidal effect. Interestingly, the impacts of surface hydrophobicity and roughness on the bactericidal effect were found to be influenced by a Gram-stain type of the tested bacteria. In addition, cell motility and shape influence BE, but research attention into these factors is lacking. It was found that hydrophobic NSS demonstrate more promising results than their hydrophilic counterparts; however, these surfaces have been overlooked. Confirming the common belief of the influence of nanofeature diameter on bactericidal property, this analysis shows the feature aspect ratio is also decisive. NSS fabricated on silicon substrates perform better than their titanium counterparts, and the success of these silicon structures maybe attributed to the fabrication processes. These insights benefit engineers and scientists alike in developing next-generation NSS. |
Keywords | bactericidal surfaces; hydrophobic; hydrophilic; nanostructured surfaces; Gram-stain type; bacterial motility; surface modification |
Contains Sensitive Content | Does not contain sensitive content |
ANZSRC Field of Research 2020 | 4003. Biomedical engineering |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | Queensland University of Technology |
https://research.usq.edu.au/item/w3xz7/trends-in-bactericidal-nanostructured-surfaces-an-analytical-perspective
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