The role of leptin in reproduction and fertility

Poster

McFarlane, Jim, Kauter, Kate and Panwar, Shalini. 2008. "The role of leptin in reproduction and fertility." Chopin, John (ed.) Australian College of Veterinary Scientists 2008 Annual Conference. Surfers Paradise, Australia 03 - 06 Jul 2008
Paper/Presentation Title

The role of leptin in reproduction and fertility

Presentation TypePoster
AuthorsMcFarlane, Jim (Author), Kauter, Kate (Author) and Panwar, Shalini (Author)
EditorsChopin, John
Journal or Proceedings TitleAustralian College of Veterinary Scientists 2008 Annual Conference - Equine Chapter Conference Program and Proceedings
Number of Pages3
Year2008
Web Address (URL) of Paperhttp://equine.anzcvs.org.au/equine/science_week/2008_proceedings/
Conference/EventAustralian College of Veterinary Scientists 2008 Annual Conference
Event Details
Australian College of Veterinary Scientists 2008 Annual Conference
Event Date
03 to end of 06 Jul 2008
Event Location
Surfers Paradise, Australia
Abstract

Leptin was originally identified as a peripheral satiety signal made by fat cells and it was proposed that as fat accumulates leptin is secreted proportionally. Leptin then crosses the blood brain barrier and signals to the hypothalamus suppressing appetite and increasing energy expenditure as it rises. It is evident that if the leptin gene or its receptor is disrupted them morbid obesity occurs. However, obesity in humans is very rarely caused by a disruption of the leptin gene or its receptor, and in many species a good correlation exists between leptin concentrations in plasma with the degree of obesity. This early finding was unexpected and led to the leptin resistance hypothesis. Further studies have revealed that leptin actually appears to be almost ubiquitously expressed in many tissues. Unfortunately despite the accumulation of a vast literature leptin still appears to be regarded as a peripheral satiety signal although the data to support this hypothesis is not substantial.

ANZSRC Field of Research 2020310999. Zoology not elsewhere classified
300305. Animal reproduction and breeding
Public Notes

No indication of copyright restrictions.

Byline AffiliationsUniversity of New England
Centre for Systems Biology
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