In vitro anti-Leishmanial effects of black tea extract components

Article


Mahdi, H. S., Al-Bashir, N. M, Saour, K. Y. and Mahdi, L. Kh.. 2005. "In vitro anti-Leishmanial effects of black tea extract components." Jordan Journal of Applied Science: Natural Science. 7 (2), pp. 38-50.
Article Title

In vitro anti-Leishmanial effects of black tea extract components

ERA Journal ID17618
Article CategoryArticle
AuthorsMahdi, H. S. (Author), Al-Bashir, N. M (Author), Saour, K. Y. (Author) and Mahdi, L. Kh. (Author)
Journal TitleJordan Journal of Applied Science: Natural Science
Journal Citation7 (2), pp. 38-50
Number of Pages13
Year2005
Place of PublicationJordan
ISSN1605-2587
Web Address (URL)http://ondemand.bl.uk/onDemand/itemDetails/show/ETOCRN172721070
Abstract

Four components of black tea extract (tannic acid, caffeine, theophylline and theobromine) exhibited antileishmanial activity against L. donovani, L. tropica and L. major, in both promastigote and axenic amastigote stages. All components showed antileishmanial activity against the three species. The concentration used ranged between (0.623-3) mg/ml. It was found that tannic acid had the greater effect on Leishmania species than other components, with ED50 range between (0.025-0.05) mg/ml after three days of exposure. Caffeine and theophylline showed a potent activity against the three species of Leishmania, with ED50 range between (0.035-1) mg/ml and (0.5-1) mg/ml respectively. In contrast the ED50 for theobromine ranged between (0.72-3) mg\ml. These results suggest further assessment of the four components of tea extract in infected laboratory animals and in humans against Leishmania infections.

KeywordsBlack tea; Leishmania
ANZSRC Field of Research 2020310101. Analytical biochemistry
320704. Medical parasitology
310799. Microbiology not elsewhere classified
Public Notes

There are no files associated with this item.

Byline AffiliationsUniversity of Baghdad, Iraq
No affiliation
Al-Nahrain University, Iraq
Institution of OriginUniversity of Southern Queensland
Permalink -

https://research.usq.edu.au/item/q35y3/in-vitro-anti-leishmanial-effects-of-black-tea-extract-components

  • 595
    total views
  • 0
    total downloads
  • 0
    views this month
  • 0
    downloads this month

Export as

Related outputs

Correction: Alhamami et al. First Emergence of Resistance to Macrolides and Tetracycline Identified in Mannheimia haemolytica and Pasteurella multocida Isolates from Beef Feedlots in Australia. Microorganisms 2021, 9, 1322
Alhamami, Tamara, Chowdhury, Piklu Roy, Gomes, Nancy, Carr, Mandi, Veltman, Tania, Khazandi, Manouchehr, Mollinger, Joanne, Deutscher, Ania T., Turni, Conny, Mahdi, Layla, Venter, Henrietta, Abraham, Sam, Djordjevic, Steven P. and Trott, D.. 2022. "Correction: Alhamami et al. First Emergence of Resistance to Macrolides and Tetracycline Identified in Mannheimia haemolytica and Pasteurella multocida Isolates from Beef Feedlots in Australia. Microorganisms 2021, 9, 1322." Microorganisms. 10 (4), pp. 1-2. https://doi.org/10.3390/microorganisms10040825
A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections
Blaskovich, Mark A. T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, J. X., Lindahl F., Ziora Z.M., Bradford T., Muldoon C., Rajaratnam P., Pelingon R., Edwards D.J., Zhang B., Amado M., Elliott A.G., ..., Cooper M.A.. 2022. "A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections." Science Translational Medicine. 14 (662), pp. 1-16. https://doi.org/10.1126/scitranslmed.abj2381
Progress in the pathobiology and genetic epidemiology of Campylobacter hepaticus, the aetiological agent of Spotty Liver Disease
Kotiw, M., Courtice, J., Mahdi, L., Wei, C., Ahmad, T., Hancock, K. and Groves, P.. 2019. "Progress in the pathobiology and genetic epidemiology of Campylobacter hepaticus, the aetiological agent of Spotty Liver Disease." 2019 Australasian Veterinary Poultry Association (AVPA) Annual Scientific Meeting. Sydney, Australia 20 - 21 Feb 2019
Spotty Liver Disease: A review of an ongoing challenge in commercial free-range egg production
Courtice, Jodi Maree, Mahdi, Layla Khalid, Groves, Peter John and Kotiw, Michael. 2018. "Spotty Liver Disease: A review of an ongoing challenge in commercial free-range egg production." Veterinary Microbiology. 227, pp. 112-118. https://doi.org/10.1016/j.vetmic.2018.08.004
First Emergence of Resistance to Macrolides and Tetracycline Identified in Mannheimia haemolytica and Pasteurella multocida Isolates from Beef Feedlots in Australia
Alhamami, Tamara, Chowdhury, Piklu Roy, Gomes, Nancy, Carr, Mandi, Veltman, Tania, Khazandi, Manouchehr, Mollinger, Joanne, Deutscher, Ania T., Turni, Conny, Mahdi, Layla, Venter, Henrietta, Abraham, Sam, Djordjevic, Steven P. and Trott, Darren J.. 2021. "First Emergence of Resistance to Macrolides and Tetracycline Identified in Mannheimia haemolytica and Pasteurella multocida Isolates from Beef Feedlots in Australia." Microorganisms. 9 (6), pp. 1-17. https://doi.org/10.3390/microorganisms9061322
Brominated indoles from a marine mollusc inhibit inflammation in a murine model of acute lung injury
Ahmad, Tarek B., Rudd, David, Benkendorff, Kirsten, Mahdi, Layla K., Pratt, Kayla-Ann, Dooley, Leanne, Wei, Chuanyu and Kotiw, Michael. 2017. "Brominated indoles from a marine mollusc inhibit inflammation in a murine model of acute lung injury." PLoS One. 12 (10). https://doi.org/10.1371/journal.pone.0186904
The pneumococcal alpha-glycerophosphate oxidase enhances nasopharyngeal colonization through binding to host glycoconjugates
Mahdi, Layla K., Higgins, Melanie A., Day, Christopher J., Tiralongo, Joe, Hartley-Tassell, Lauren E., Jennings, Michael P., Gordon, David L., Paton, Adrienne W., Paton, James C. and Ogunniyi, Abiodun D.. 2017. "The pneumococcal alpha-glycerophosphate oxidase enhances nasopharyngeal colonization through binding to host glycoconjugates." EBioMedicine. 18, pp. 236-243. https://doi.org/10.1016/j.ebiom.2017.03.002
Application of RAPD- PCR to differentiate among Aeromonas spp
Jaladet, M. S. J., M., Layla Kh. and Zaineb, M. N.. 2004. "Application of RAPD- PCR to differentiate among Aeromonas spp ." Journal of Al-Nahrain University. 7, pp. 48-56.
Chemical characterization and anti-bacterial activity of black tea extract components
Mahdi, H. S., Mahdi, L. Kh. and Saour, K. Y.. 2005. "Chemical characterization and anti-bacterial activity of black tea extract components ." Journal of The Faculty of Medicine Baghdad. 47 (2), pp. 174-178.
Preparation of C-reactive protein latex reagent of human serum
Alshalchi, Sahar A., Mahdi, Layla K. and Sabar, Muna. 2006. "Preparation of C-reactive protein latex reagent of human serum ." Iraqi Journal of Biotechnology. 5 (1), pp. 112-122.
The variable region of the pneumococcal pathogenicity island 1 is responsible for the unusually high virulence of a serotype 1 isolate
Harvey, Richard M., Trappetti, Claudia, Mahdi, Layla K., Wang, Hui, McAllister, Lauren J., Scalvini, Alexandra, Paton, Adrienne W. and Paton, James C.. 2016. "The variable region of the pneumococcal pathogenicity island 1 is responsible for the unusually high virulence of a serotype 1 isolate." Infection and Immunity. 84 (3), pp. 822-832. https://doi.org/10.1128/IAI.01454-15
A functional genomics catalogue of activated transcription factors during pathogenesis of pneumococcal disease
Mahdi, Layla K., Deihim, Tahereh, Zamansani, Fatemeh, Fruzangohar, Mario, Adelson, David L., Paton, James C., Ogunniyi, Abiodun D. and Ebrahimie, Esmaeil. 2014. "A functional genomics catalogue of activated transcription factors during pathogenesis of pneumococcal disease." BMC Genomics. 15 (1), pp. 1-15. https://doi.org/10.1186/1471-2164-15-769
Comparative GO: a web application for comparative gene ontology and gene ontology-based gene selection in bacteria
Fruzangohar, Mario, Ebrahimie, Esmaeil, Ogunniyi, Abiodun D., Mahdi, Layla K., Paton, James C. and Adelson, David L.. 2013. "Comparative GO: a web application for comparative gene ontology and gene ontology-based gene selection in bacteria." PLoS One. 8 (3), pp. e58759-e58767. https://doi.org/10.1371/journal.pone.0058759
A transcription factor contributes to pathogenesis and virulence in Streptococcus pneumoniae
Mahdi, Layla K., Ebrahimie, Esmaeil, Adelson, David L., Paton, James C. and Ogunniyi, Abiodun D.. 2013. "A transcription factor contributes to pathogenesis and virulence in Streptococcus pneumoniae." PLoS One. 8 (8), pp. e70862-e70871. https://doi.org/10.1371/journal.pone.0070862
Identification of a novel pneumococcal vaccine antigen preferentially expressed during meningitis in mice
Mahdi, Layla K., Wang, Hui, Van der Hoek, Mark B., Paton, James C. and Ogunniyi, Abiodun D.. 2012. "Identification of a novel pneumococcal vaccine antigen preferentially expressed during meningitis in mice." Journal of Clinical Investigation. 122 (6), pp. 2208-2220. https://doi.org/10.1172/JCI45850
Identification of genes that contribute to the pathogenesis of invasive Pneumococcal Disease by In Vivo transcriptomic analysis
Ogunniyi, Abiodun D., Mahdi, Layla K., Trappetti, Claudia, Verhoeven, Nadine, Mermans, Daphne, Van der Hoek, Mark B., Plumptre, Charles D. and Paton, James C.. 2012. "Identification of genes that contribute to the pathogenesis of invasive Pneumococcal Disease by In Vivo transcriptomic analysis." Infection and Immunity. 80 (9), pp. 3268-3278. https://doi.org/10.1128/IAI.00295-12
Characterization of pneumococcal genes involved in bloodstream invasion in a mouse model
Mahdi, Layla K., Van der Hoek, Mark B., Ebrahimie, Esmaeil, Paton, James C. and Ogunniyi, Abiodun D.. 2015. "Characterization of pneumococcal genes involved in bloodstream invasion in a mouse model." PLoS One. 10 (11), pp. 1-15. https://doi.org/10.1371/journal.pone.0141816
Correction: Comparative GO: A Web Application for Comparative Gene Ontology and Gene Ontology-Based Gene Selection in Bacteria
Fruzangohar, Mario, Ebrahimie, Esmaeil, Ogunniyi, Abiodun D., Mahdi, Layla K., Paton, James C. and Adelson, David L.. 2015. "Correction: Comparative GO: A Web Application for Comparative Gene Ontology and Gene Ontology-Based Gene Selection in Bacteria." PLoS One. 10 (4). https://doi.org/10.1371/journal.pone.0125537
Association of Helicobacter pylori with colorectal cancer development
Alsamak, Fadi Fouad, Abdulamir, Ahmed Sahib, Mahdi, Layla Khalid, Alnaib, Khalid and Abu Bakar, Fatimah. 2010. "Association of Helicobacter pylori with colorectal cancer development." Asian Biomedicine. 4 (4), pp. 609-618.
Central role of manganese in regulation of stress responses, physiology, and metabolism in streptococcus pneumoniae
Ogunniyi, Abiodun D., Mahdi, Layla K., Jennings, Michael P., McEwan, Alastair G., McDevitt, Christopher A., Van der Hoek, Mark B., Bagley, Christopher J., Hoffmann, Peter, Gould, Katherine A. and Paton, James C.. 2010. "Central role of manganese in regulation of stress responses, physiology, and metabolism in streptococcus pneumoniae." Journal of Bacteriology. 192 (17), pp. 4489-4497. https://doi.org/10.1128/JB.00064-10
Investigation into the controversial association of Streptococcus gallolyticus with colorectal cancer and adenoma
Abdulamir, Ahmed S., Hafidh, Rand R., Mahdi, Layla K., Al-jeboori, Tarik and Abu bakar, Fatimah. 2009. "Investigation into the controversial association of Streptococcus gallolyticus with colorectal cancer and adenoma." BMC Cancer. 9 (1), pp. 403-415. https://doi.org/10.1186/1471-2407-9-403
Pneumococcal histidine triad proteins are regulated by the Zn2+-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H
Ogunniyi, Abiodun D., Grabowicz, Marcin, Mahdi, Layla K., Cook, Jan, Gordon, David L., Sadlon, Tania A. and Paton, James C.. 2009. "Pneumococcal histidine triad proteins are regulated by the Zn2+-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H." The FASEB Journal. 23 (3), pp. 731-738. https://doi.org/10.1096/fj.08-119537
The interplay between p53 and p21 tumor suppressor proteins in the transformation of colorectal adenoma to carcinoma
Abdulamir, A. S., Hafidh, R. R., Mahdi, L. K., Al-jeboori, T. R., Abu bakar, F. and Abbas, K. A.. 2008. "The interplay between p53 and p21 tumor suppressor proteins in the transformation of colorectal adenoma to carcinoma." American Journal of Immunology. 4 (2), pp. 14-22. https://doi.org/10.3844/ajisp.2008.14.22
Pneumococcal virulence gene expression and host cytokine profiles during pathogenesis of invasive disease
Mahdi, Layla K., Ogunniyi, Abiodun D., LeMessurier, Kim S. and Paton, James C.. 2008. "Pneumococcal virulence gene expression and host cytokine profiles during pathogenesis of invasive disease ." Infection and Immunity. 76 (2), pp. 646-657. https://doi.org/10.1128/IAI.01161-07
Prevalence and etiology of urinary stones in hospitalized patients in Baghdad
Qaader, D. S., Yousif, S. Y. and Mahdi, L. K.. 2006. "Prevalence and etiology of urinary stones in hospitalized patients in Baghdad." Eastern Mediterranean Health Journal. 12 (6), pp. 853-861.
First report of Escherichia coli O157 among Iraqi children
Shebib, Z. A., Abdul Ghani, Z. G. and Mahdi, L. Kh.. 2003. "First report of Escherichia coli O157 among Iraqi children." Eastern Mediterranean Health Journal. 9 (1-2), pp. 159-166.