Combined gene selection methods for microarray data analysis
Paper
Paper/Presentation Title | Combined gene selection methods for microarray data analysis |
---|---|
Presentation Type | Paper |
Authors | Hu, Hong (Author), Li, Jiuyong (Author), Wang, Hua (Author) and Daggard, Grant (Author) |
Editors | Gabrys, Bogdan, Howlett, Robert J. and Jain, Lakhmi C. |
Journal or Proceedings Title | Lecture Notes in Computer Science (Book series) |
Journal Citation | 4251, pp. 976-983 |
Number of Pages | 8 |
Year | 2006 |
Publisher | Springer |
Place of Publication | Germany |
ISSN | 1611-3349 |
0302-9743 | |
ISBN | 9783540465355 |
Digital Object Identifier (DOI) | https://doi.org/10.1007/11892960_117 |
Web Address (URL) of Paper | https://link.springer.com/chapter/10.1007/11892960_117 |
Conference/Event | 10th International Conference on Knowledge-Based Intelligent Information and Engineering Systems (KES 2006) |
Event Details | 10th International Conference on Knowledge-Based Intelligent Information and Engineering Systems (KES 2006) Parent International Conference on Knowledge-Based and Intelligent Information and Engineering Systems Delivery In person Event Date 09 to end of 11 Oct 2006 Event Location Bournemouth, United Kingdom |
Abstract | In recent years, the rapid development of DNA Microarray technology has made it possible for scientists to monitor the expression level of thousands of genes in a single experiment. As a new technology, Microarray data presents some fresh challenges to scientists since Microarray data contains a large number of genes (around tens thousands) with a small number of samples (around hundreds). Both filter and wrapper gene selection methods aim to select the most informative genes among the massive data in order to reduce the size of the expression database. Gene selection methods are used in both data preprocessing and classification stages. We have conducted some experiments on different existing gene selection methods to preprocess Microarray data for classification by benchmark algorithms SVMs and C4.5. The study suggests that the combination of filter and wrapper methods in general improve the accuracy performance of gene expression Microarray data classification. The study also indicates that not all filter gene selection methods help improve the performance of classification. The experimental results show that among tested gene selection methods, Correlation Coefficient is the best gene selection method for improving the classification accuracy on both SVMs and C4.5 classification algorithms. |
Keywords | classification; gene selection; Microarray data |
ANZSRC Field of Research 2020 | 469999. Other information and computing sciences not elsewhere classified |
461399. Theory of computation not elsewhere classified | |
310505. Gene expression (incl. microarray and other genome-wide approaches) | |
Public Notes | File reproduced in accordance with the copyright policy of the publisher/author. |
Byline Affiliations | Department of Mathematics and Computing |
Department of Biological and Physical Sciences |
https://research.usq.edu.au/item/9y0x6/combined-gene-selection-methods-for-microarray-data-analysis
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