Carbon-based nanostructures for cancer therapy and drug delivery applications
Article
Bagheri, Babak, Surwase, Sachin S., Lee, Su Sam, Park, Heewon, Faraji Rad, Zahra, Trevaskis, Natalie L. and Kim, Yeu-Chun. 2022. "Carbon-based nanostructures for cancer therapy and drug delivery applications." Journal of Materials Chemistry B. 10 (48), pp. 9944-9967. https://doi.org/10.1039/d2tb01741e
| Article Title | Carbon-based nanostructures for cancer therapy and drug delivery applications |
|---|---|
| ERA Journal ID | 201059 |
| Article Category | Article |
| Authors | Bagheri, Babak, Surwase, Sachin S., Lee, Su Sam, Park, Heewon, Faraji Rad, Zahra, Trevaskis, Natalie L. and Kim, Yeu-Chun |
| Journal Title | Journal of Materials Chemistry B |
| Journal Citation | 10 (48), pp. 9944-9967 |
| Number of Pages | 24 |
| Year | 2022 |
| Publisher | The Royal Society of Chemistry |
| Place of Publication | United Kingdom |
| ISSN | 2050-750X |
| 2050-7518 | |
| Digital Object Identifier (DOI) | https://doi.org/10.1039/d2tb01741e |
| Web Address (URL) | https://pubs.rsc.org/en/content/articlelanding/2022/TB/D2TB01741E |
| Abstract | Synthesis, design, characterization, and application of carbon-based nanostructures (CBNSs) as drug carriers have attracted a great deal of interest over the past half of the century because of their promising chemical, thermal, physical, optical, mechanical, and electrical properties and their structural diversity. CBNSs are well-known in drug delivery applications due to their unique features such as easy cellular uptake, high drug loading ability, and thermal ablation. CBNSs, including carbon nanotubes, fullerenes, nanodiamond, graphene, and carbon quantum dots have been quite broadly examined for drug delivery systems. This review not only summarizes the most recent studies on developing carbon-based nanostructures for drug delivery (e.g. delivery carrier, cancer therapy and bioimaging), but also tries to deal with the challenges and opportunities resulting from the expansion in use of these materials in the realm of drug delivery. This class of nanomaterials requires advanced techniques for synthesis and surface modifications, yet a lot of critical questions such as their toxicity, biodistribution, pharmacokinetics, and fate of CBNSs in biological systems must be answered. |
| Keywords | Controlled drug delivery; Diseases; Oncology; Semiconductor quantum dots; Targeted drug delivery |
| ANZSRC Field of Research 2020 | 401807. Nanomaterials |
| 400302. Biomaterials | |
| Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
| Funder | National Research Foundation of Korea |
| Byline Affiliations | Korea Advanced Institute of Science and Technology (KAIST), Korea |
| University of Southern Queensland | |
| School of Engineering | |
| Monash University |
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