Assessment of electric field distribution in anisotropic cortical and subcortical regions under the influence of tDCS
Article
Article Title | Assessment of electric field distribution in anisotropic cortical and subcortical regions under the influence of tDCS |
---|---|
ERA Journal ID | 2051 |
Article Category | Article |
Authors | Shahid, Salman (Author), Wen, Peng (Author) and Ahfock, Tony (Author) |
Journal Title | Bioelectromagnetics |
Journal Citation | 35 (1), pp. 41-57 |
Number of Pages | 17 |
Year | 2014 |
Place of Publication | Hoboken, NJ. United States |
ISSN | 0197-8462 |
1521-186X | |
Digital Object Identifier (DOI) | https://doi.org/10.1002/bem.21814 |
Web Address (URL) | http://onlinelibrary.wiley.com/doi/10.1002/bem.21814/pdf |
Abstract | The focus of this study is to estimate the contribution of regional anisotropic conductivity on the spatial distribution of induced electric field across the gray matter (GM), white matter (WM) and sub-cortical regions under transcranial direct current stimulation (tDCS). The assessment was conducted using a passive high-resolution finite element head model with inhomogeneous and variable anisotropic conductivities derived from the diffusion tensor data. Electric field distribution was evaluated across different cortical as well as sub-cortical regions under four bi-cephalic electrode configurations. Results indicate that regional tissue heterogeneity and anisotropy cause the pattern of induced field to vary in orientation and strength when compared to the isotropic scenario. Different electrode montages resulted in distinct distribution patterns with noticeable variations in field strengths. The effect of anisotropy is highly montage dependent and directional conductivity has a more profound effect in defining the strength of the induced field. The inclusion of anisotropy in the GM and sub-cortical regions has a significant effect on the strength and spatial distribution of the induced electric field. Under (C3–Fp2) montage, the inclusion of GM and sub-cortical anisotropy increased the average percentage difference in the electric field strength of brain from 5% (WM anisotropy only) to 34%. In terms of patterns distribution, the topographic errors increased from 9.9% (WM anisotropy only) to 40% across the brain. |
Keywords | anisotropy; tissue electrical conductivity; transcranial direct current stimulation |
ANZSRC Field of Research 2020 | 510502. Medical physics |
320999. Neurosciences not elsewhere classified | |
400305. Biomedical instrumentation | |
Public Notes | © 2013 Wiley Periodicals, Inc. Published version deposited in accordance with the copyright policy of the publisher. |
Byline Affiliations | School of Mechanical and Electrical Engineering |
School of Agricultural, Computational and Environmental Sciences | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q2199/assessment-of-electric-field-distribution-in-anisotropic-cortical-and-subcortical-regions-under-the-influence-of-tdcs
1809
total views93
total downloads0
views this month0
downloads this month