Gastroesophageal reflux disease following laparoscopic vertical sleeve gastrectomy and laparoscopic roux-en-Y gastric bypass: meta-analysis and systematic review of 5-year data
Article
| Article Title | Gastroesophageal reflux disease following laparoscopic vertical sleeve gastrectomy and laparoscopic roux-en-Y gastric bypass: meta-analysis and systematic review of 5-year data |
|---|---|
| ERA Journal ID | 16037 |
| Article Category | Article |
| Authors | Memon, Muhammed A, Osland, Emma, Yunus, Rossita M, Alam, Khorshed, Hoque, Zahirul and Khan, Shahjahan |
| Journal Title | Diseases of the Esophagus |
| Journal Citation | 37 (3), pp. 593-617 |
| Number of Pages | 12 |
| Year | 2024 |
| Publisher | Oxford University Press |
| Place of Publication | United States |
| ISSN | 1120-8694 |
| 1442-2050 | |
| Digital Object Identifier (DOI) | https://doi.org/10.1093/dote/doad063 |
| Web Address (URL) | https://academic.oup.com/dote/advance-article-abstract/doi/10.1093/dote/doad063/7335804?redirectedFrom=fulltext |
| Abstract | To compare 5-year gastroesophageal reflux outcomes following Laparoscopic Vertical Sleeve Gastrectomy (LVSG) and Laparoscopic Roux-en-Y gastric bypass (LRYGB) based on high quality randomized controlled trials (RCTs). We conducted a sub-analysis of our systematic review and meta-analysis of RCTs of primary LVSG and LRYGB procedures in adults for 5-year post-operative complications (PROSPERO CRD42018112054). Electronic databases were searched from January 2015 to July 2021 for publications meeting inclusion criteria. The Hartung-Knapp-Sidik-Jonkman random effects model was utilized to estimate weighted mean differences where meta-analysis was possible. Bias and certainty of evidence was assessed using the Cochrane Risk of Bias Tool 2 and GRADE. Four RCTs were included (LVSG n = 266, LRYGB n = 259). An increase in adverse GERD outcomes were observed at 5 years postoperatively in LVSG compared to LRYGB in all outcomes considered: Overall worsened GERD, including the development de novo GERD, occurred more commonly following LVSG compared to LRYGB (OR 5.34, 95% CI 1.67 to 17.05; p = 0.02; I2 = 0%; (Moderate level of certainty); Reoperations to treat severe GERD (OR 7.22, 95% CI 0.82 to 63.63; p = 0.06; I2 = 0%; High level of certainty) and non-surgical management for worsened GERD (OR 3.42, 95% CI 1.16 to 10.05; p = 0.04; I2 = 0%; Low level of certainty) was more common in LVSG patients. LVSG is associated with the development and worsening of GERD symptoms compared to LRYGB at 5 years postoperatively leading to either introduction/increased pharmacological requirement or further surgical treatment. Appropriate patient/surgical selection is critical to minimize these postoperative risks. |
| Keywords | bariatric surgery, gastroesophageal reflux disease, laparoscopic, meta-analysis, roux-en-y gastric bypass, sleeve gastrectomy, systematic review |
| Contains Sensitive Content | Does not contain sensitive content |
| ANZSRC Field of Research 2020 | 420314. Multimorbidity |
| 420603. Health promotion | |
| Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
| Byline Affiliations | School of Business |
| Centre for Health Research | |
| School of Mathematics, Physics and Computing | |
| Sunnybank Obesity Centre, Australia | |
| University of Queensland | |
| University of Bolton, United Kingdom | |
| Royal Brisbane and Women’s Hospital, Australia | |
| University of Malaya, Malaysia | |
| Asian University of Bangladesh, Bangladesh |
https://research.usq.edu.au/item/z3984/gastroesophageal-reflux-disease-following-laparoscopic-vertical-sleeve-gastrectomy-and-laparoscopic-roux-en-y-gastric-bypass-meta-analysis-and-systematic-review-of-5-year-data
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