Common molecular and pathophysiological underpinnings of delirium and Alzheimer’s disease: Molecular signatures and therapeutic indications
Article
Article Title | Common molecular and pathophysiological underpinnings of delirium and Alzheimer’s disease: Molecular signatures and therapeutic indications |
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ERA Journal ID | 15806 |
Article Category | Article |
Authors | Mosharaf, Md Parvez, Alam, Khorshed, Gow, Jeff, Mahumud, Rashidul Alam and Mollah, Md Nurul Haque |
Journal Title | BMC Geriatrics |
Journal Citation | 24 |
Article Number | 716 |
Number of Pages | 20 |
Year | 2024 |
Publisher | BioMed Central Ltd. |
Place of Publication | United Kingdom |
ISSN | 1471-2318 |
Digital Object Identifier (DOI) | https://doi.org/10.1186/s12877-024-05289-3 |
Web Address (URL) | https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-024-05289-3 |
Abstract | Background: Delirium and Alzheimer's disease (AD) are common causes of cognitive dysfunction among older adults. These neurodegenerative diseases share a common and complex relationship, and can occur individually or concurrently, increasing the chance of permanent mental dysfunction. However, the common molecular pathophysiology, key proteomic biomarkers, and functional pathways are largely unknown, whereby delirium is superimposed on AD and dementia. |
Keywords | Alzheimer’s disease; Molecular docking simulation; Essential drug targets; Drug repurposing; Common signaling pathways; Delirium |
Article Publishing Charge (APC) Funding | Researcher |
Contains Sensitive Content | Does not contain sensitive content |
ANZSRC Field of Research 2020 | 380202. Econometric and statistical methods |
420606. Social determinants of health | |
420314. Multimorbidity | |
Byline Affiliations | School of Business |
University of Rajshahi, Bangladesh | |
Centre for Health Research | |
University of KwaZulu-Natal, South Africa | |
University of Sydney |
https://research.usq.edu.au/item/z90q1/common-molecular-and-pathophysiological-underpinnings-of-delirium-and-alzheimer-s-disease-molecular-signatures-and-therapeutic-indications
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