Ravenic acid, a new tetramic acid isolated from a cultured microfungus, penicillium sp.

Article

Michael, Adam P., Grace, Emily J., Kotiw, Mike and Barrow, Russell A.. 2002. "Ravenic acid, a new tetramic acid isolated from a cultured microfungus, penicillium sp." Journal of Natural Products. 65 (9), pp. 1360-1362. https://doi.org/10.1021/np0200358
Article Title

Ravenic acid, a new tetramic acid isolated from a cultured microfungus, penicillium sp.

ERA Journal ID40471
Article CategoryArticle
AuthorsMichael, Adam P. (Author), Grace, Emily J. (Author), Kotiw, Mike (Author) and Barrow, Russell A. (Author)
Journal TitleJournal of Natural Products
Journal Citation65 (9), pp. 1360-1362
Number of Pages3
Year2002
Place of PublicationUnited States
ISSN0163-3864
1520-6025
Digital Object Identifier (DOI)https://doi.org/10.1021/np0200358
Web Address (URL)https://pubs.acs.org/doi/10.1021/np0200358
Abstract

A new antibiotic polyene tetramic acid, ravenic acid (2), has been isolated from the mycelia of a cultured fungus, Penicillium sp. The structure of ravenic acid was determined by detailed spectroscopic analysis and the major isomer identified as possessing (3Z, 7E, 9E, 11E, 13E) stereochemistry.

Keywordsravenic acid; penicillium sp; drug isolation; drug structure; mycelium; proton nuclear magnetic resonance; spectroscopy; stereochemistry; X ray diffraction
Contains Sensitive ContentDoes not contain sensitive content
ANZSRC Field of Research 2020310705. Mycology
320501. Medical biochemistry - amino acids and metabolites
320603. Medical molecular engineering of nucleic acids and proteins
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Byline AffiliationsAustralian National University
Department of Biological and Physical Sciences
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