Correlation between fatty acid profile and anti-inflammatory activity in common Australian sea-food by-products

Article

Ahmad, Tarek B., Rudd, David, Kotiw, Michael, Liu, Lei and Benkendorff, Kirsten. 2019. "Correlation between fatty acid profile and anti-inflammatory activity in common Australian sea-food by-products." Marine Drugs. 17 (3), pp. 1-20. https://doi.org/10.3390/md17030155
Article Title

Correlation between fatty acid profile and anti-inflammatory activity in common Australian sea-food by-products

ERA Journal ID14994
Article CategoryArticle
AuthorsAhmad, Tarek B. (Author), Rudd, David (Author), Kotiw, Michael (Author), Liu, Lei (Author) and Benkendorff, Kirsten (Author)
Journal TitleMarine Drugs
Journal Citation17 (3), pp. 1-20
Article Number155
Number of Pages20
Year2019
Place of PublicationSwitzerland
ISSN1660-3397
Digital Object Identifier (DOI)https://doi.org/10.3390/md17030155
Web Address (URL)https://www.mdpi.com/1660-3397/17/3/155
Abstract

Marine organisms are a rich source of biologically active lipids with anti-inflammatory activities. These lipids may be enriched in visceral organs that are waste products from common seafood. Gas chromatography-mass spectrometry and fatty acid methyl ester (FAME) analyses were performed to compare the fatty acid compositions of lipid extracts from some common seafood organisms, including octopus (Octopus tetricus), squid (Sepioteuthis australis), Australian sardine (Sardinops sagax), salmon (Salmo salar) and school prawns (Penaeus plebejus). The lipid extracts were tested for anti-inflammatory activity by assessing their inhibition of nitric oxide (NO) and tumor necrosis factor alpha (TNFα) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 mouse cells. The lipid extract from both the flesh and waste tissue all contained high amounts of polyunsaturated fatty acids (PUFAs) and significantly inhibited NO and TNFα production. Lipid extracts from the cephalopod mollusks S. australis and O. tetricus demonstrated the highest total PUFA content, the highest level of omega 3 (ω-3) PUFAs, and the highest anti-inflammatory activity. However, multivariate analysis indicates the complex mixture of saturated, monounsaturated, and polyunsaturated fatty acids may all influence the anti-inflammatory activity of marine lipid extracts. This study confirms that discarded parts of commonly consumed seafood species provide promising sources for the development of new potential anti-inflammatory nutraceuticals.

Keywordsseafood waste; polyunsaturated fatty acid; NO inhibition; fish oil; marine nutraceuticals
ANZSRC Field of Research 2020420899. Traditional, complementary and integrative medicine not elsewhere classified
Byline AffiliationsSouthern Cross University
Division of Research and Innovation
Institution of OriginUniversity of Southern Queensland
Permalink -

https://research.usq.edu.au/item/q58zw/correlation-between-fatty-acid-profile-and-anti-inflammatory-activity-in-common-australian-sea-food-by-products

Log in to edit

Download files

Published Version
marinedrugs-17-00155.pdf
License: CC BY 4.0
File access level: Anyone

  • 142
    total views
  • 74
    total downloads
  • 1
    views this month
  • 1
    downloads this month

Export as

Related outputs

Fire-retardant and high-strength polymeric materials enabled by supramolecular aggregates
Liu, Lei, Zhu, Menghe, Feng, Jiabing, Peng, Hong, Shi, Yongqian, Gao, Jiefeng, Tang, Long-Cheng and Song, Pingan. 2024. "Fire-retardant and high-strength polymeric materials enabled by supramolecular aggregates." Aggregate. https://doi.org/10.1002/agt2.494
Strike 3 … Out! Investigating Pre-Game Moods, Performance, and Mental Health of Softball Umpires
Lamont-Mills, Andrea, Houison, Ronald J., Kotiw, Michael and Terry, Peter C.. 2024. "Strike 3 … Out! Investigating Pre-Game Moods, Performance, and Mental Health of Softball Umpires." Sports. 12 (2). https://doi.org/10.3390/sports12020050
2D MXenes for Fire Retardancy and Fire-Warning Applications: Promises and Prospects
Liu, Lei, Feng, Jiabing, Xue, Yijiao, Chevali, Venkata, Zhang, Yubai, Shi, Yongqian, Tang, Longcheng and Song, Pingan. 2023. "2D MXenes for Fire Retardancy and Fire-Warning Applications: Promises and Prospects ." Advanced Functional Materials. 33 (9). https://doi.org/10.1002/adfm.202212124
Identification of epidemiological risk factors for spotty liver disease in cage-free layer flocks in houses with fully slatted flooring in Australia
Gao, Yuanshuo K., Singh, Mini, Muir, Wendy I., Kotiw, Michael and Groves, Peter J.. 2023. "Identification of epidemiological risk factors for spotty liver disease in cage-free layer flocks in houses with fully slatted flooring in Australia." Poultry Science. 102 (12). https://doi.org/10.1016/j.psj.2023.103139
Scratch area as an epidemiological risk factor for Spotty Liver Disease in cage-free layers in Australia
Gao, Yuanshuo K., Singh, Mini, Muir, Wendy I., Kotiw, Michael and Groves, Peter J.. 2023. "Scratch area as an epidemiological risk factor for Spotty Liver Disease in cage-free layers in Australia." Poultry Science. 102 (10). https://doi.org/10.1016/j.psj.2023.102922
Detection, characterization, and persistence of Campylobacter hepaticus, the cause of spotty liver disease in layer hens
Courtice, Jodi M., Ahmad, Tarek B., Wei, Chuanyu, Mahdi, Layla K., Palmieri, Chiara, Juma, Sarah, Groves, Peter J., Hancock, Kerry, Korolik, Victoria, Petrovsky, Nikolai and Kotiw, Michael. 2023. "Detection, characterization, and persistence of Campylobacter hepaticus, the cause of spotty liver disease in layer hens." Poultry Science. 102 (7). https://doi.org/10.1016/j.psj.2022.102462
An iron phenylphosphinate@graphene oxide nanohybrid enabled flame-retardant, mechanically reinforced, and thermally conductive epoxy nanocomposites
Chen, Qiang, Liu, Lei, Zhang, Anlin, Wang, Wenduo, Wang, Zhengzhou, Zhang, Jianzhong, Feng, Jiabing, Huo, Siqi, Zeng, Xuesen and Song, Pingan. 2023. "An iron phenylphosphinate@graphene oxide nanohybrid enabled flame-retardant, mechanically reinforced, and thermally conductive epoxy nanocomposites." Chemical Engineering Journal. 454. https://doi.org/10.1016/j.cej.2022.140424
Superhydrophobic self-extinguishing cotton fabrics for electromagnetic interference shielding and human motion detection
Liu, Lei, Ma, Zhewen, Zhu, Menghe, Liu, Lina, Dai, Jinfeng, Shi, Yongqian, Gao, Jiefeng, Dinh, Toan, Nguyen, Thanh, Tang, Long-Cheng and Song, Pingan. 2023. "Superhydrophobic self-extinguishing cotton fabrics for electromagnetic interference shielding and human motion detection ." Journal of Materials Science and Technology. 132, pp. 59-68. https://doi.org/10.1016/j.jmst.2022.05.036
Bioinspired Strong, Tough, and Biodegradable Poly(Vinyl Alcohol) and its Applications as Substrates for Humidity Sensors
Liu, Lei, Xu, Xiaodong, Zhu, Menghe, Cui, Xihua, Feng, Jiabing, Faraji Rad, Zahra, Wang, Hao and Song, Pingan. 2023. "Bioinspired Strong, Tough, and Biodegradable Poly(Vinyl Alcohol) and its Applications as Substrates for Humidity Sensors." Advanced Materials Technologies. https://doi.org/10.1002/admt.202201414
Small multiamine molecule enabled fire-retardant polymeric materials with enhanced strength, toughness, and self-healing properties
Liu, Lei, Zhu, Menghe, Ma, Zhewen, Xu, Xiaodong, Dai, Jinfeng, Yu, Youming, Seraji, Seyed Mohsen, Wang, Hao and Song, Pingan. 2022. "Small multiamine molecule enabled fire-retardant polymeric materials with enhanced strength, toughness, and self-healing properties." Chemical Engineering Journal. 400, pp. 1-11. https://doi.org/10.1016/j.cej.2022.135645
A reactive copper-organophosphate-MXene heterostructure enabled antibacterial, self-extinguishing and mechanically robust polymer nanocomposites
Liu, Lei, Zhu, Menghe, Ma, Zhewen, Xu, Xiaodong, Seraji, Seyed Mohsen, Yu, Bin, Sun, Ziqi, Wang, Hao and Song, Pingan. 2022. "A reactive copper-organophosphate-MXene heterostructure enabled antibacterial, self-extinguishing and mechanically robust polymer nanocomposites." Chemical Engineering Journal. 430, pp. 1-12. https://doi.org/10.1016/j.cej.2021.132712
A highly fire-retardant rigid polyurethane foam capable of fire-warning
Ma, Zhewen, Zhang, Jianzhong, Liu, Lei, Zheng, Hua, Dai, Jinfeng, Tang, Long-Cheng and Song, Pingan. 2021. "A highly fire-retardant rigid polyurethane foam capable of fire-warning." Composites Communications. 29, pp. 1-6. https://doi.org/10.1016/j.coco.2021.101046
Recent advances in fire-retardant rigid polyurethane foam
Zhu, Menghe, Ma, Zhewen, Liu, Lei, Zhang, Jianzhong, Huo, Siqi and Song, Pingan. 2021. "Recent advances in fire-retardant rigid polyurethane foam." Journal of Materials Science and Technology. 112, pp. 315-328. https://doi.org/10.1016/j.jmst.2021.09.062
Dynamic Nanoconfinement Enabled Highly Stretchable and Supratough Polymeric Materials with Desirable Healability and Biocompatibility
Liu, Lei, Zhu, Menghe, Xu, Xiaodong, Ma, Zhewen, Jiang, Zhen, Pich, Andrij, Wang, Hao, Song, Pingan and Li, X.. 2021. "Dynamic Nanoconfinement Enabled Highly Stretchable and Supratough Polymeric Materials with Desirable Healability and Biocompatibility." Advanced Materials. 33 (51), pp. 1-11. https://doi.org/10.1002/adma.202105829
Scalable, Robust, Low-Cost, and Highly Thermally Conductive Anisotropic Nanocomposite Films for Safe and Efficient Thermal Management
Chen, Qiang, Ma, Zhewen, Wang, Zhengzhou, Liu, Lei, Zhu, Menghe, Lei, Weiwei and Song, Pingan. 2021. "Scalable, Robust, Low-Cost, and Highly Thermally Conductive Anisotropic Nanocomposite Films for Safe and Efficient Thermal Management." Advanced Functional Materials. https://doi.org/10.1002/adfm.202110782
Bioinspired, Strong, and Tough Nanostructured Poly(vinyl alcohol)/Inositol Composites: How Hydrogen-Bond Cross-Linking Works?
Xu, Xiaodong, Li, Lujuan, Seraji, Seyed Mohsen, Liu, Lei, Jiang, Zhen, Xu, Zhiguang, Li, Xin, Zhao, Sheng, Wang, Hao and Song, Pingan. 2020. "Bioinspired, Strong, and Tough Nanostructured Poly(vinyl alcohol)/Inositol Composites: How Hydrogen-Bond Cross-Linking Works?" Macromolecules. 54 (20), pp. 9510-9521. https://doi.org/10.1021/acs.macromol.1c01725
Bioinspired, Highly Adhesive, Nanostructured Polymeric Coatings for Superhydrophobic Fire-Extinguishing Thermal Insulation Foam
Ma, Zhewen, Liu, Xiaochen, Xu, Xiaodong, Liu, Lei, Yu, Bin, Maluk, Cristian, Huang, Guobo, Wang, Hao and Song, Pingan. 2021. "Bioinspired, Highly Adhesive, Nanostructured Polymeric Coatings for Superhydrophobic Fire-Extinguishing Thermal Insulation Foam." ACS Nano. 15 (7), pp. 11667-11680. https://doi.org/10.1021/acsnano.1c02254
Functionalizing MXene towards highly stretchable, ultratough, fatigue- and fire-resistant polymer nanocomposites
Liu, Lei, Zhu, Menghe, Shi, Yongqian, Xu, Xiaodong, Ma, Zhewen, Yu, Bin, Fu, Shenyuan, Huang, Guobo, Wang, Hao and Song, Pingan. 2021. "Functionalizing MXene towards highly stretchable, ultratough, fatigue- and fire-resistant polymer nanocomposites." Chemical Engineering Journal. 424, pp. 1-13. https://doi.org/10.1016/j.cej.2021.130338
Molecularly Engineered Lignin-Derived Additives Enable Fire-Retardant, UV-Shielding, and Mechanically Strong Polylactide Biocomposites
Yang, Haitang, Shi, Bingbing, Xue, Yijiao, Ma, Zhewen, Liu, Lina, Liu, Lei, Yu, Youming, Zhang, Zhanying, Annamalai, Pratheep K. and Song, Pingan. 2021. "Molecularly Engineered Lignin-Derived Additives Enable Fire-Retardant, UV-Shielding, and Mechanically Strong Polylactide Biocomposites." Biomacromolecules. 22 (4), pp. 1432-1444. https://doi.org/10.1021/acs.biomac.0c01656
Water governs the mechanical properties of poly(vinyl alcohol)
Li, Lujuan, Xu, Xiaodong, Liu, Lei, Song, Pingan, Cao, Qianqian, Xu, Zhiguang, Fang, Zhengping and Wang, Hao. 2021. "Water governs the mechanical properties of poly(vinyl alcohol)." Polymer. 213, pp. 1-12. https://doi.org/10.1016/j.polymer.2020.123330
Catalysis based on ferroelectrics: controllable chemical reaction with boosted efficiency
Wan, Tsz Lok, Ge, Lei, Pan, Yangli, Yuan, Qinghong, Liu, Lei, Sarina, Sarina and Kou, Liangzhi. 2021. "Catalysis based on ferroelectrics: controllable chemical reaction with boosted efficiency." Nanoscale. 13 (15), pp. 7096-7107. https://doi.org/10.1039/d1nr00847a
Phosphorus-containing flame retardant epoxy thermosets: Recent advances and future perspectives
Huo, Siqi, Song, Pingan, Yu, Bin, Ran, Shiya, Chevali, Venkata, Liu, Lei, Fang, Zhengping and Wang, Hao. 2021. "Phosphorus-containing flame retardant epoxy thermosets: Recent advances and future perspectives." Progress in Polymer Science. 114, pp. 1-36. https://doi.org/10.1016/j.progpolymsci.2021.101366
Spotty Liver Disease: A South East Queensland Perspective and Research Progress
Kotiw, Michael and Courtice, Jodi. 2018. "Spotty Liver Disease: A South East Queensland Perspective and Research Progress." Poultry Information Exchange and Australasian Milling Conference (PIX/AMC 2018). Gold Coast, Australia 03 - 05 Jun 2018
Field Trials of a Spotty Liver Disease Vaccine: Vaccine Trial 1: Small scale Trial
Courtice, Jodi M., Ahmad, Tarek B., Wei, Chuanyu, Groves, Peter J., Gao, Karen, Phoon, Olivia C., Palmieri, Chiara, Petrovsky, Nikolai and Kotiw, Michael. 2020. "Field Trials of a Spotty Liver Disease Vaccine: Vaccine Trial 1: Small scale Trial." 2020 Australasian Veterinary Poultry Association (AVPA) Annual Scientific Meeting. Online 20 - 21 May 2020
Progress in the pathobiology and genetic epidemiology of Campylobacter hepaticus, the aetiological agent of Spotty Liver Disease
Kotiw, M., Courtice, J., Mahdi, L., Wei, C., Ahmad, T., Hancock, K. and Groves, P.. 2019. "Progress in the pathobiology and genetic epidemiology of Campylobacter hepaticus, the aetiological agent of Spotty Liver Disease." 2019 Australasian Veterinary Poultry Association (AVPA) Annual Scientific Meeting. Sydney, Australia 20 - 21 Feb 2019
Spotty Liver Disease: A review of an ongoing challenge in commercial free-range egg production
Courtice, Jodi Maree, Mahdi, Layla Khalid, Groves, Peter John and Kotiw, Michael. 2018. "Spotty Liver Disease: A review of an ongoing challenge in commercial free-range egg production." Veterinary Microbiology. 227, pp. 112-118. https://doi.org/10.1016/j.vetmic.2018.08.004
Spotty Liver Disease and Risk Factors
Gao, Yuanshou Karen, Singh, Mini, Muir, Wendy, Williamson, Sarah, Sharpe, Sue, Kotiw, Mike and Groves, Peter. 2021. "Spotty Liver Disease and Risk Factors." 2021 Australasian Veterinary Poultry Association (AVPA) Annual Scientific Meeting. Online 11 - 12 Feb 2021
Polyphosphoramide-intercalated MXene for simultaneously enhancing the thermal stability, flame retardancy and mechanical properties of polylactide
Xue, Yijiao, Feng, Jiabing, Huo, Siqi, Song, Pingan, Yu, Bin, Liu, Lei and Wang, Hao. 2020. "Polyphosphoramide-intercalated MXene for simultaneously enhancing the thermal stability, flame retardancy and mechanical properties of polylactide." Chemical Engineering Journal. 397, pp. 1-11. https://doi.org/10.1016/j.cej.2020.125336
Grafting Lignin with Bioderived Polyacrylates for Low-Cost, Ductile, and Fully Biobased Poly(lactic acid) Composite
Sun, Yiqi, Ma, Zhewen, Xu, Xiaodong, Liu, Xiaohuan, Liu, Lina, Huang, Guobo, Liu, Lei, Wang, Hao and Song, Pingan. 2020. "Grafting Lignin with Bioderived Polyacrylates for Low-Cost, Ductile, and Fully Biobased Poly(lactic acid) Composite." ACS Sustainable Chemistry and Engineering. 8 (5), pp. 2267-2276. https://doi.org/10.1021/acssuschemeng.9b06593
Rheumatic heart disease: A review of the current status of global research activity
Dooley, Leanne M., Ahmad, Tarek B., Pandey, Manisha, Good, Micheal F. and Kotiw, Michael. 2021. "Rheumatic heart disease: A review of the current status of global research activity." Autoimmunity Reviews. 20 (2), pp. 1-23. https://doi.org/10.1016/j.autrev.2020.102740
Viral vs bacterial vectors for vaccine delivery
Kotiw, Michael. 2011. "Viral vs bacterial vectors for vaccine delivery." Mei, Xiaodan (ed.) 3rd Annual World Vaccine Congress: The Future of Global Vaccines (WCV 2011). Beijing, China 23 - 25 Mar 2011 Dalian, China.
Review of anti-inflammatory, immune-modulatory and wound healing properties of molluscs
Ahmad, Tarek B., Liu, Lei, Kotiw, Michael and Benkendorff, Kirsten. 2018. "Review of anti-inflammatory, immune-modulatory and wound healing properties of molluscs." Journal of Ethnopharmacology. 210, pp. 156-178. https://doi.org/10.1016/j.jep.2017.08.008
Brominated indoles from a marine mollusc inhibit inflammation in a murine model of acute lung injury
Ahmad, Tarek B., Rudd, David, Benkendorff, Kirsten, Mahdi, Layla K., Pratt, Kayla-Ann, Dooley, Leanne, Wei, Chuanyu and Kotiw, Michael. 2017. "Brominated indoles from a marine mollusc inhibit inflammation in a murine model of acute lung injury." PLoS One. 12 (10). https://doi.org/10.1371/journal.pone.0186904
Anti-inflammatory activity and structure-activity relationships of brominated indoles from a marine mollusc
Ahmad, Tarek B., Rudd, David, Smith, Joshua, Kotiw, Michael, Mouatt, Peter, Seymour, Lisa M., Liu, Lei and Benkendorff, Kirsten. 2017. "Anti-inflammatory activity and structure-activity relationships of brominated indoles from a marine mollusc." Marine Drugs. 15 (5), pp. 1-19. https://doi.org/10.3390/md15050133
A screening method for the detection of fungi with potentially antimicrobial secondary metabolites
Boddington, Morwenna, Kotiw, Michael and Dearnaley, John. 2008. "A screening method for the detection of fungi with potentially antimicrobial secondary metabolites." ASM 2008: Changing Times. Melbourne, Australia 06 - 10 Jul 2008 Melbourne, Australia.
The diversity and antimicrobial activity of Preussia sp. Endophytes isolated from Australian dry rainforests
Mapperson, Rachel R., Kotiw, Michael, Davis, Rohan A. and Dearnaley, John D. W.. 2014. "The diversity and antimicrobial activity of Preussia sp. Endophytes isolated from Australian dry rainforests." Current Microbiology: an international journal. 68 (1), pp. 30-37. https://doi.org/10.1007/s00284-013-0415-5
Immunological response to parenteral vaccination with recombinant hepatitis B virus surface antigen virus-like particles expressing Helicobacter pylori KatA epitopes in a murine H. pylori challenge model
Kotiw, Michael, Johnson, Megan, Pandey, Manisha, Fry, Scott, Hazell, Stuart L., Netter, Hans J., Good, Michael F. and Olive, Colleen. 2012. "Immunological response to parenteral vaccination with recombinant hepatitis B virus surface antigen virus-like particles expressing Helicobacter pylori KatA epitopes in a murine H. pylori challenge model ." Clinical and Vaccine Immunology. 19 (2), pp. 268-276. https://doi.org/10.1128/CVI.05295-11
Ravenic acid, a new tetramic acid isolated from a cultured microfungus, penicillium sp.
Michael, Adam P., Grace, Emily J., Kotiw, Mike and Barrow, Russell A.. 2002. "Ravenic acid, a new tetramic acid isolated from a cultured microfungus, penicillium sp." Journal of Natural Products. 65 (9), pp. 1360-1362. https://doi.org/10.1021/np0200358
Xanthones from a microfungus of the genus Xylaria
Healy, Peter C., Hocking, Ailsa, Tran-Dinh, Nai, Pitt, John I., Shivas, Roger G., Mitchell, Jennifer K., Kotiw, Mike and Davis, Rohan A.. 2004. "Xanthones from a microfungus of the genus Xylaria." Phytochemistry: the international journal of plant chemistry, plant biochemistry and molecular biology. 65 (16), pp. 2373-2378. https://doi.org/10.1016/j.phytochem.2004.07.019
Phomoxins B and C: polyketides from an endophytic fungus of the genus eupenicillium
Davis, Rohan A., Andjic, Vesna, Kotiw, Michael and Shivas, Roger G.. 2005. "Phomoxins B and C: polyketides from an endophytic fungus of the genus eupenicillium." Phytochemistry: the international journal of plant chemistry, plant biochemistry and molecular biology. 66 (23), pp. 2771-2775. https://doi.org/10.1016/j.phytochem.2005.09.004
A RAPD-PCR genotyping assay which correlates with serotypes of group B streptococci
Zhang, G. W., Kotiw, M. and Daggard, G.. 2002. "A RAPD-PCR genotyping assay which correlates with serotypes of group B streptococci." Letters in Applied Microbiology. 35 (3), pp. 247-250. https://doi.org/10.1046/j.1472-765X.2002.01177.x
Late-onset and recurrent neonatal group B streptococcal disease associated with breast milk transmission
Kotiw, Michael, Zhang, Gwang W., Daggard, Grant, Reiss-Levy, Elizabeth, Tapsall, John W. and Numa, Andrew. 2003. "Late-onset and recurrent neonatal group B streptococcal disease associated with breast milk transmission." Pediatric and Developmental Pathology. 6 (3), pp. 251-256. https://doi.org/10.1007/s10024-001-0276-y
Synthesis of the fungal natural product (-)-xylariamide A
Kotiw, Michael and Davis, Rohan A.. 2005. "Synthesis of the fungal natural product (-)-xylariamide A." Tetrahedron Letters: the international journal for the rapid publication of all preliminary communications in organic chemistry. 46 (31), pp. 5199-5201. https://doi.org/10.1016/j.tetlet.2005.05.114
Caelestines A-D, Brominated Quinolinecarboxylic Acids from the Australian Ascidian Aplidium caelestis
Yin, Sheng, Boyle, Glen M., Carroll, Anthony R., Kotiw, Michael, Dearnaley, John, Quinn, Ronald J. and Davis, Rohan A.. 2010. "Caelestines A-D, Brominated Quinolinecarboxylic Acids from the Australian Ascidian Aplidium caelestis." Journal of Natural Products. 73 (9), pp. 1586-1589. https://doi.org/10.1021/np100329w
Detection of anti-TNFα activity in canine hyperimmune serum using a TNFα inhibition assay
Kotiw, Michael, Morgan, Michael, Taylor, Stephen M. and Shiels, Ian A.. 2010. "Detection of anti-TNFα activity in canine hyperimmune serum using a TNFα inhibition assay ." Veterinary Clinical Pathology. 39 (1), pp. 46-52. https://doi.org/10.1111/j.1939-165X.2009.00166.x
Anti-inflammatory activity of hyperimmune plasma in a lipopolysaccharide-mediated rat air pouch model of inflammation
Essien, Bryan E. and Kotiw, Michael. 2012. "Anti-inflammatory activity of hyperimmune plasma in a lipopolysaccharide-mediated rat air pouch model of inflammation." Inflammation. 35 (1), pp. 58-64. https://doi.org/10.1007/s10753-010-9289-x
Effect of canine hyperimmune plasma on TNFa and inflammatory cell levels in a lipopolysaccharide-mediated rat air pouch model of inflammation
Strunin, Dmitry, Essien, Bryan, Kotiw, Michael and Butler, Harry. 2009. "Effect of canine hyperimmune plasma on TNFa and inflammatory cell levels in a lipopolysaccharide-mediated rat air pouch model of inflammation." Reinhart, Konrad (ed.) Sepsis 2009: Critical Care Conference. Amsterdam, Netherlands 11 - 14 Nov 2009 https://doi.org/10.1186/cc8064
A mathematical model to account for quantitative iterative effect of TNF-α positive feedback mechanism on inflammatory cascade in TLR-4 mediated TNF-α signaling pathway
Roberts, Tony, Essien, Bryan, Kotiw, Michael, Butler, Harry and Strunin, Dmitry. 2008. "A mathematical model to account for quantitative iterative effect of TNF-α positive feedback mechanism on inflammatory cascade in TLR-4 mediated TNF-α signaling pathway." Ragan, Mark (ed.) 19th International Conference on Genome Informatics (GIW 2008). Gold Coast, Australia 01 - 03 Dec 2008 London, United Kingdom.
In vitro effect of canine hyperimmune sera on TNFa activity
Kotiw, Michael, Shiels, I. A., Wilson, R. P. and Reeve-Johnson, Lloyd. 2006. "In vitro effect of canine hyperimmune sera on TNFa activity." Journal of Veterinary Pharmacology and Therapeutics. 29 (Supplement 1), pp. 100-101. https://doi.org/10.1111/j.1365-2885.2006.00761.x
The effect of equine hyperimmune sera on TNF alpha activity in a L929 cell bioassay
Kotiw, M., Raghaven, C., Johnson, M., Shiels, I. A. and Wilson, R. P.. 2006. "The effect of equine hyperimmune sera on TNF alpha activity in a L929 cell bioassay." Bryden, W. L. (ed.) AESS 2006: Australian Equine Science Symposium: Research for the 21st Century Horse Industry: From Genomics to the Winning Post. Gold Coast, Australia 13 - 14 Jun 2006 Gold Coast, Australia.
Biological methods: a novel course in undergraduate biology
Kotiw, Michael, Learmonth, Robert P. and Sutherland, Mark W.. 1999. "Biological methods: a novel course in undergraduate biology." Biochemical Education. 27 (3), pp. 131-134. https://doi.org/10.1016/S0307-4412(99)00002-3
The relevance of human rights to health status in Australian Aboriginal and Torres Strait Islander communities
Smallwood, Gracelyn, White, Colin and Kotiw, Michael. 1997. "The relevance of human rights to health status in Australian Aboriginal and Torres Strait Islander communities." Health and Human Rights: an international journal. 2 (2), pp. 127-136.
In vitro and in vivo determination of ant-TNFa activity in canine plasma from donors subject to pre conditioning with endotoxin
Kotiw, Michael, Morgan, Michael, Lopez, Jesus, Taylor, Steven and Shiels, Ian. 2007. "In vitro and in vivo determination of ant-TNFa activity in canine plasma from donors subject to pre conditioning with endotoxin." Marshall, John (ed.) SEPSIS 2007: International Sepsis Forum ISF . Paris, France 26 - 29 Sep 2007 London, United Kingdom. https://doi.org/10.1186/cc6002
In the footsteps of Florey: utilising cultured microfungi in the search for new antibiotics
Parker, C., Barrow, Russell, Bloor, S. J., Grace, Emily J., Michael, Adam P., Thompson, Christopher and Kotiw, Michael. 2001. "In the footsteps of Florey: utilising cultured microfungi in the search for new antibiotics." Bernhardt, Debra (ed.) FACS 2001: 9th Asian Chemical Congress . Brisbane, Australia 02 - 04 Jul 2001 Brisbane, Australia.
Exploring the potential for dual vaccination against Hepatitis B virus and Helicobacter pylori using a recombinant virus like particle
Kotiw, Michael, Olive, C., Johnson, Megan, Pandy, M., Fry, Scott Robert, Hazell, Stuart L., Netter, H. and Good, M.. 2006. "Exploring the potential for dual vaccination against Hepatitis B virus and Helicobacter pylori using a recombinant virus like particle." Sirtori, Patrizia (ed.) 6th National Congress of the Italian Society of Virology - a joint meeting with the Virus Group of the Society for General Microbiology (UK). Orvieto, Italy 18 - 20 Sep 2006 Italy.
Isochromophilone IX, a novel GABA-containing metabolite isolated from a cultured fungus, Penicillium sp.
Michael, Adam P., Grace, Emily J., Kotiw, Michael and Barrow, Russell A.. 2003. "Isochromophilone IX, a novel GABA-containing metabolite isolated from a cultured fungus, Penicillium sp." Australian Journal of Chemistry: an international journal for chemical science. 56 (1), pp. 13-15. https://doi.org/10.1071/CH02021