Xanthones from a microfungus of the genus Xylaria
Article
Article Title | Xanthones from a microfungus of the genus Xylaria |
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ERA Journal ID | 1371 |
Article Category | Article |
Authors | Healy, Peter C. (Author), Hocking, Ailsa (Author), Tran-Dinh, Nai (Author), Pitt, John I. (Author), Shivas, Roger G. (Author), Mitchell, Jennifer K. (Author), Kotiw, Mike (Author) and Davis, Rohan A. (Author) |
Journal Title | Phytochemistry: the international journal of plant chemistry, plant biochemistry and molecular biology |
Journal Citation | 65 (16), pp. 2373-2378 |
Number of Pages | 6 |
Year | 2004 |
Publisher | Elsevier |
Place of Publication | United Kingdom |
ISSN | 0031-9422 |
1873-3700 | |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.phytochem.2004.07.019 |
Web Address (URL) | https://www.sciencedirect.com/science/article/pii/S0031942204003577 |
Abstract | Chemical investigations of a microfungus Xylaria sp. isolated from the Australian rainforest tree Glochidion ferdinandi have afforded two new natural products, 2-hydroxy-6-methyl-8-methoxy-9-oxo-9H-xanthene-1-carboxylic acid (1) and 2-hydroxy-6-hydroxymethyl-8-methoxy-9-oxo-9H-xanthene-1-carboxylic acid (2). Compound 1 has previously been synthesised but only partially characterised. Methylation of 1 using diazomethane afforded the crystalline compound 2,8-dimethoxy-6-methyl-9-oxo-9H-xanthene-1-carboxylic acid methyl ester (3), whose structure was determined by single crystal X-ray analysis. This paper reports the full spectroscopic characterisation of compounds 1–3 by NMR, UV, IR and MS data. All compounds were inactive in a brine shrimp lethality assay and several antimicrobial screens. |
Keywords | microfungus; Xylaria sp.; rainforest tree; glochidion ferdinandi; natural products; secondary metabolites; Xanthone |
Contains Sensitive Content | Does not contain sensitive content |
ANZSRC Field of Research 2020 | 321402. Clinical pharmacology and therapeutics |
310705. Mycology | |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | Griffith University |
Food Science Australia | |
Department of Primary Industries and Fisheries, Queensland | |
Centre for Systems Biology |
https://research.usq.edu.au/item/9y841/xanthones-from-a-microfungus-of-the-genus-xylaria
2005
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