Isochromophilone IX, a novel GABA-containing metabolite isolated from a cultured fungus, Penicillium sp.
Article
Michael, Adam P., Grace, Emily J., Kotiw, Michael and Barrow, Russell A.. 2003. "Isochromophilone IX, a novel GABA-containing metabolite isolated from a cultured fungus, Penicillium sp." Australian Journal of Chemistry: an international journal for chemical science. 56 (1), pp. 13-15. https://doi.org/10.1071/CH02021
| Article Title | Isochromophilone IX, a novel GABA-containing metabolite isolated from a cultured fungus, Penicillium sp. |
|---|---|
| ERA Journal ID | 1314 |
| Article Category | Article |
| Authors | Michael, Adam P. (Author), Grace, Emily J. (Author), Kotiw, Michael (Author) and Barrow, Russell A. (Author) |
| Journal Title | Australian Journal of Chemistry: an international journal for chemical science |
| Journal Citation | 56 (1), pp. 13-15 |
| Number of Pages | 3 |
| Year | 2003 |
| Place of Publication | Melbourne, Australia |
| ISSN | 0004-9425 |
| 1445-0038 | |
| Digital Object Identifier (DOI) | https://doi.org/10.1071/CH02021 |
| Web Address (URL) | http://www.publish.csiro.au/?act=view_file&file_id=CH02021.pdf |
| Abstract | Isochromophilone IX, a novel antibiotic active component was isolated from a penicillium species and investigated. Isochromophilone IX displays a specific rotation with the same sign as isochromophilone VI. It was found that isochromophilone represents the first occurrence of an γ-amino butyric acid (GABA) containing metabolite among only four naturally occuring members of this structure class. |
| Keywords | amino acids; fungi; high performance liquid chromatography; isomers; mass spectrometry; metabolites |
| ANZSRC Field of Research 2020 | 310701. Bacteriology |
| 349999. Other chemical sciences not elsewhere classified | |
| 320501. Medical biochemistry - amino acids and metabolites | |
| 320603. Medical molecular engineering of nucleic acids and proteins | |
| Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
| Byline Affiliations | Australian National University |
| Department of Biological and Physical Sciences | |
| Institution of Origin | University of Southern Queensland |
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