There is no association between the omega-3 index and depressive symptoms in patients with heart disease who are low fish consumers
Article
Article Title | There is no association between the omega-3 index and depressive symptoms in patients with heart disease who are low fish consumers |
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ERA Journal ID | 16185 |
Article Category | Article |
Authors | Cai, Shaoxin (Author), Coates, Alison M. (Author), Buckley, Jonathan D. (Author), Berry, Narelle M. (Author), Burres, Lisa (Author), Beltrame, John (Author), Howe, Peter R. C. (Author) and Schrader, Geoffrey (Author) |
Journal Title | Heart Lung and Circulation |
Journal Citation | 26 (3), pp. 276-284 |
Number of Pages | 9 |
Year | 2017 |
Place of Publication | Australia |
ISSN | 1443-9506 |
1444-2892 | |
Digital Object Identifier (DOI) | https://doi.org/10.1016/j.hlc.2016.07.003 |
Web Address (URL) | http://www.sciencedirect.com/science/article/pii/S1443950616315360?via%3Dihub |
Abstract | Background: Long chain Omega-3 polyunsaturated fatty acids (LCn3PUFAs) may improve cardiovascular health and depression. This study investigated the relationships between erythrocyte membrane LCn3PUFA status, depression and angina symptoms in patients with heart disease. Methods: We recruited 91 patients (65 males and 26 females, mean age 59.2 ± 10.3 years) with heart disease and depressive symptoms (Center for Epidemiological Studies Depression Scale, CES-D ≥ 16) and low fish/fish oil intakes. The Omega-3 Index (EPA+DHA) of erythrocyte membranes (as a percentage of total fatty acids) was assessed by gas chromatography. Depression status was measured by both self-report and clinician-report scales; CES-D and the Hamilton depression scale (HAM-D). Angina symptoms were measured using the Seattle Angina Questionnaire and the Canadian Cardiovascular Society Classification for Angina Pectoris. Results: The mean Omega-3 Index was 4.8 ± 1.0% (±SD). Depression scores measured by CES-D and HAM-D were 29.2 ± 8.8 (moderate to severe) and 11.0 ± 5.7 (mild) (arbitrary units) respectively reflecting a different perception of depressive symptoms between patients and clinicians. Angina status was inversely associated with depression scores (r > -0.26, P < 0.03). There were no significant relationships between individual LCn3PUFA or the Omega-3 Index and either the depression scores or the angina symptoms. Conclusion: Worse angina status was associated with worse depression, but the Omega-3 Index was not associated with symptoms of depression or angina in patients with heart disease. |
Keywords | depression; heart disease; Omega-3 Index; |
ANZSRC Field of Research 2020 | 321004. Nutritional science |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | University of South Australia |
Flinders University | |
University of Adelaide | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q411x/there-is-no-association-between-the-omega-3-index-and-depressive-symptoms-in-patients-with-heart-disease-who-are-low-fish-consumers
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