Effects of low-fat diets differing in protein and carbohydrate content on cardiometabolic risk factors during weight loss and weight maintenance in obese adults with type 2 diabetes
Article
Article Title | Effects of low-fat diets differing in protein and carbohydrate content on cardiometabolic risk factors during weight loss and weight maintenance in obese adults with type 2 diabetes |
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ERA Journal ID | 211152 |
Article Category | Article |
Authors | Watson, Nerylee (Author), Dyer, Kathryn (Author), Buckley, Jonathan (Author), Brinkworth, Grant (Author), Coates, Alison (Author), Parfitt, Gaynor (Author), Howe, Peter (Author), Noakes, Manny (Author) and Murphy, Karen (Author) |
Journal Title | Nutrients |
Journal Citation | 8 (5) |
Number of Pages | 15 |
Year | 2016 |
Publisher | MDPI AG |
Place of Publication | Switzerland |
ISSN | 2072-6643 |
Digital Object Identifier (DOI) | https://doi.org/10.3390/nu8050289 |
Web Address (URL) | http://www.mdpi.com/2072-6643/8/5/289 |
Abstract | Despite evidence for the benefits of higher-protein (HP) diets in weight loss, their role in type 2 diabetes mellitus (T2DM) management and weight maintenance is not clear. This randomised study compared the effects of a HP diet (38% carbohydrate, 30% protein, 29% fat) to a isocaloric higher-carbohydrate diet (HC: 53%:21%:23%) on cardiometabolic risk factors for 12 weeks in energy restriction (~30% reduction) followed by 12 weeks of energy balance whilst performing regular exercise. Outcomes were measured at baseline and the end of each phase. Sixty-one overweight/obese adults (BMI (body mass index) 34.3 ± 5.1 kg/m2, aged 55 ± 8 years) with T2DM who commenced the study were included in the intention-to-treat analysis including the 17 participants (HP n = 9, HC n = 8) who withdrew. Following weight loss (M ± SEM: -7.8 ± 0.6 kg), there were significant reductions in HbA1c (–1.4% ± 0.1%, p < 0.001) and several cardiometabolic health risk factors. Improvements were sustained for 12 weeks when weight was stabilised and weight loss maintained. Both the HP and HC dietary patterns with concurrent exercise may be effective strategies for weight loss and weight maintenance in T2DM although further studies are needed to determine the longer term effects of weight maintenance. |
Keywords | type 2 diabetes; glycaemic; cardiovascular disease risk;weight loss;weightmaintenance; obesity |
ANZSRC Field of Research 2020 | 321099. Nutrition and dietetics not elsewhere classified |
Byline Affiliations | University of South Australia |
Commonwealth Scientific and Industrial Research Organisation (CSIRO), Australia | |
University of Newcastle | |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q4119/effects-of-low-fat-diets-differing-in-protein-and-carbohydrate-content-on-cardiometabolic-risk-factors-during-weight-loss-and-weight-maintenance-in-obese-adults-with-type-2-diabetes
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