The impact of pre- and post-image processing techniques on deep learning frameworks: A comprehensive review for digital pathology image analysis
Article
Salvi, Massimo, Acharya, U. Rajendra, Molinari, Filippo and Meiburger, Kristen M.. 2021. "The impact of pre- and post-image processing techniques on deep learning frameworks: A comprehensive review for digital pathology image analysis." Computers in Biology and Medicine. 128. https://doi.org/10.1016/j.compbiomed.2020.104129
| Article Title | The impact of pre- and post-image processing techniques on deep learning frameworks: A comprehensive review for digital pathology image analysis |
|---|---|
| ERA Journal ID | 5040 |
| Article Category | Article |
| Authors | Salvi, Massimo, Acharya, U. Rajendra, Molinari, Filippo and Meiburger, Kristen M. |
| Journal Title | Computers in Biology and Medicine |
| Journal Citation | 128 |
| Article Number | 104129 |
| Number of Pages | 24 |
| Year | 2021 |
| Publisher | Elsevier |
| ISSN | 0010-4825 |
| 1879-0534 | |
| Digital Object Identifier (DOI) | https://doi.org/10.1016/j.compbiomed.2020.104129 |
| Web Address (URL) | https://www.sciencedirect.com/science/article/pii/S0010482520304601? |
| Abstract | Recently, deep learning frameworks have rapidly become the main methodology for analyzing medical images. Due to their powerful learning ability and advantages in dealing with complex patterns, deep learning algorithms are ideal for image analysis challenges, particularly in the field of digital pathology. The variety of image analysis tasks in the context of deep learning includes classification (e.g., healthy vs. cancerous tissue), detection (e.g., lymphocytes and mitosis counting), and segmentation (e.g., nuclei and glands segmentation). The majority of recent machine learning methods in digital pathology have a pre- and/or post-processing stage which is integrated with a deep neural network. These stages, based on traditional image processing methods, are employed to make the subsequent classification, detection, or segmentation problem easier to solve. Several studies have shown how the integration of pre- and post-processing methods within a deep learning pipeline can further increase the model's performance when compared to the network by itself. The aim of this review is to provide an overview on the types of methods that are used within deep learning frameworks either to optimally prepare the input (pre-processing) or to improve the results of the network output (post-processing), focusing on digital pathology image analysis. Many of the techniques presented here, especially the post-processing methods, are not limited to digital pathology but can be extended to almost any image analysis field. |
| Keywords | Deep learning; Histology; Image analysis ; Pre-processing ; Post-processing ; Digital pathology |
| ANZSRC Field of Research 2020 | 400306. Computational physiology |
| Byline Affiliations | Polytechnic University of Turin, Italy |
| Ngee Ann Polytechnic, Singapore | |
| Asia University, Taiwan | |
| Singapore University of Social Sciences (SUSS), Singapore |
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