Superior robust ultrathin single-crystalline silicon carbide membrane as a versatile platform for biological applications
Article
Article Title | Superior robust ultrathin single-crystalline silicon carbide membrane as a versatile platform for biological applications |
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ERA Journal ID | 40638 |
Article Category | Article |
Authors | Nguyen, Tuan-Khoa (Author), Phan, Hoang-Phuong (Author), Kamble, Harshad (Author), Vadivelu, Raja (Author), Dinh, Toan (Author), Iacopi, Alan (Author), Walker, Glenn (Author), Hold, Leonie (Author), Nguyen, Nam-Trung (Author) and Dao, Dzung Viet (Author) |
Journal Title | ACS Applied Materials and Interfaces |
Journal Citation | 9 (48), pp. 41641-41647 |
Number of Pages | 7 |
Year | 2017 |
Publisher | American Chemical Society |
Place of Publication | United States |
ISSN | 1944-8244 |
1944-8252 | |
Digital Object Identifier (DOI) | https://doi.org/10.1021/acsami.7b15381 |
Web Address (URL) | https://pubs.acs.org/doi/full/10.1021/acsami.7b15381 |
Abstract | Micromachined membranes are promising platforms for cell culture thanks to their miniaturization and integration capabilities. Possessing chemical inertness, biocompatibility, and integration, silicon carbide (SiC) membranes have attracted great interest toward biological applications. In this paper, we present the batch fabrication, mechanical characterizations, and cell culture demonstration of robust ultrathin epitaxial deposited SiC membranes. The as-fabricated ultrathin SiC membranes, with an ultrahigh aspect ratio (length/thickness) of up to 20 000, possess high a fracture strength up to 2.95 GPa and deformation up to 50 μm. A high optical transmittance of above 80% at visible wavelengths was obtained for 50 nm membranes. The as-fabricated membranes were experimentally demonstrated as an excellent substrate platform for bio-MEMS/NEMS cell culture with the cell viability rate of more than 92% after 72 h. The ultrathin SiC membrane is promising for in vitro observations/imaging of bio-objects with an extremely short optical access. |
Keywords | cell culture; LPCVD; membrane; silicon carbide; ultrathin |
ANZSRC Field of Research 2020 | 401705. Microelectromechanical systems (MEMS) |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | Griffith University |
Institution of Origin | University of Southern Queensland |
https://research.usq.edu.au/item/q5q41/superior-robust-ultrathin-single-crystalline-silicon-carbide-membrane-as-a-versatile-platform-for-biological-applications
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