Electrohydrodynamic Nebuliser (eNEB) for Direct Pulmonary Drug Delivery Application
Paper
Paper/Presentation Title | Electrohydrodynamic Nebuliser (eNEB) for Direct Pulmonary Drug Delivery Application |
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Presentation Type | Paper |
Authors | Vu, Trung-Hieu, Mai, Luan Ngoc, Nguyen, Tuan-Hung, Tran, Dang Ngoc, Nguyen, Tuan-Khoa, Nguyen, Thanh, Fastier-Woollel, Jarred, Tran, Canh-Dung, Dinh, Toan, Nguyen, Hong-Quan, Dao, Dzung Viet and Dau, Van Thanh |
Journal or Proceedings Title | Proceedings of the 36th IEEE International Conference on Micro Electro Mechanical Systems (MEMS) |
Journal Citation | pp. 366-369 |
Article Number | 10052181 |
Number of Pages | 4 |
Year | 2023 |
Publisher | IEEE (Institute of Electrical and Electronics Engineers) |
Place of Publication | United States |
ISBN | 9781665493086 |
Digital Object Identifier (DOI) | https://doi.org/10.1109/MEMS49605.2023.10052181 |
Web Address (URL) of Paper | https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10052181 |
Web Address (URL) of Conference Proceedings | https://ieeexplore.ieee.org/xpl/conhome/10052111/proceeding |
Conference/Event | 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS) |
Event Details | 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS) Parent IEEE International Conference on Micro Electro Mechanical Systems (MEMS) Delivery In person Event Date 15 to end of 19 Jan 2023 Event Location Munich, Germany Event Web Address (URL) |
Abstract | We present a new method of nebulisation based on electrohydrodynamic atomisation (EHDA) for use in pulmonary drug delivery application. Our device named electrohydrodynamic nebuliser (eNEB) is a single-step platform to directly produce and deliver micro/nano particles. We applied the working principle of EHDA but employed a sharp pin as reference electrode. As the device works, solution is atomised into plume of particles with sizes under 1 µm and the pin generates ion wind which results in not only reduction of net charge but also propulsion in the particle cloud. The device was able to fabricate particles and fibres from polyvinylidene fluoride (PVDF), at concentrations 5 wt% and 20 wt%. A 5-day growth of breast cancer cells was assayed to investigate the effectiveness for medical applications. |
Keywords | Ion wind; neutralisation; automised; plume; electrohydrodynamic |
ANZSRC Field of Research 2020 | 401803. Nanoelectromechanical systems |
401204. Computational methods in fluid flow, heat and mass transfer (incl. computational fluid dynamics) | |
510599. Medical and biological physics not elsewhere classified | |
Public Notes | Files associated with this item cannot be displayed due to copyright restrictions. |
Byline Affiliations | Griffith University |
Vietnam National University, Vietnam | |
School of Engineering | |
Centre for Future Materials |
https://research.usq.edu.au/item/x40q5/electrohydrodynamic-nebuliser-eneb-for-direct-pulmonary-drug-delivery-application
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